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Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

Neurons and Cognition · Quantitative Biology 2024-11-06 Alec MacIver , Hina Shaheen

This paper investigates the distributed stochastic nonconvex and nonsmooth composite optimization problem. Existing stochastic typically rely on uniform step size strictly bounded by global network parameters, such as the maximum node…

Optimization and Control · Mathematics 2026-03-10 Yangming Zhang , Yongyang Xiong , Jinming Xu , Keyou You , Yang Shi

Based on the use of different exponential bases to define class-dependent error bounds, a new and highly efficient asymmetric boosting scheme, coined as AdaBoostDB (Double-Base), is proposed. Supported by a fully theoretical derivation…

Computer Vision and Pattern Recognition · Computer Science 2015-07-09 Iago Landesa-Vázquez , José Luis Alba-Castro

We present two multimodal fusion-based deep learning models that consume ASR transcribed speech and acoustic data simultaneously to classify whether a speaker in a structured diagnostic task has Alzheimer's Disease and to what degree,…

Computation and Language · Computer Science 2021-07-01 Morteza Rohanian , Julian Hough , Matthew Purver

Trajectory optimization is becoming increasingly powerful in addressing motion planning problems of underactuated robotic systems. Numerous prior studies solve such a class of large non-convex optimal control problems in a hierarchical…

Robotics · Computer Science 2020-03-19 Ziyi Zhou , Ye Zhao

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

Biomarker discovery in neurodegenerative diseases requires robust, interpretable frameworks capable of integrating high-dimensional multi-omics data under low-sample conditions. We propose a novel ensemble approach combining Graph Attention…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Byeonghee Lee , Joonsung Kang

Feature selection often leads to increased model interpretability, faster computation, and improved model performance by discarding irrelevant or redundant features. While feature selection is a well-studied problem with many widely-used…

Machine Learning · Statistics 2021-02-12 Tianyi Yao , Genevera I. Allen

In the high-dimensional landscape, addressing the challenges of covariance regression with high-dimensional covariates has posed difficulties for conventional methodologies. This paper addresses these hurdles by presenting a novel approach…

Methodology · Statistics 2024-04-11 Yuheng He , Changliang Zou , Yi Zhao

Partial differential equations (PDEs) with near singular solutions pose significant challenges for traditional numerical methods, particularly in complex geometries where mesh generation and adaptive refinement become computationally…

Numerical Analysis · Mathematics 2025-07-24 Yangtao Deng , Qiaolin He , Xiaoping Wang

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

We consider the high-dimensional discriminant analysis problem. For this problem, different methods have been proposed and justified by establishing exact convergence rates for the classification risk, as well as the l2 convergence results…

Machine Learning · Statistics 2013-06-28 Mladen Kolar , Han Liu

Recent research has shown that pre-trained vision-language models are effective at identifying out-of-distribution (OOD) samples by using negative labels as guidance. However, employing consistent negative labels across different OOD…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Yabin Zhang , Lei Zhang

Partial differential equations (PDEs) are fundamental for modeling complex natural and physical phenomena. In many real-world applications, however, observational data are extremely sparse, which severely limits the applicability of both…

Machine Learning · Computer Science 2026-05-14 Zhonghao Li , Chaoyu Liu , Qian Zhang

Bridging the gap between data-rich training regimes and observation-sparse deployment conditions remains a central challenge in spatiotemporal field reconstruction, particularly when target domains exhibit distributional shifts,…

Machine Learning · Computer Science 2026-01-30 Xingyue Zhang , Yuxuan Bao , Mars Liyao Gao , J. Nathan Kutz

Conventional multimodal data integration methods provide a comprehensive assessment of the shared or unique structure within each individual data type but suffer from several limitations such as the inability to handle high-dimensional data…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Matthew Drexler , Benjamin Risk , James J Lah , Suprateek Kundu , Deqiang Qiu

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

Multimodal fusion has emerged as a promising paradigm for disease diagnosis and prognosis, integrating complementary information from heterogeneous data sources such as medical images, clinical records, and radiology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Chongyu Qu , Zhengyi Lu , Yuxiang Lai , Thomas Z. Li , Junchao Zhu , Junlin Guo , Juming Xiong , Yanfan Zhu , Yuechen Yang , Allen J. Luna , Kim L. Sandler , Bennett A. Landman , Yuankai Huo

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Guangqian Yang , Kangrui Du , Zhihan Yang , Ye Du , Yongping Zheng , Shujun Wang

Deep learning-based diagnostic models often suffer performance drops due to distribution shifts between training (source) and test (target) domains. Collecting and labeling sufficient target domain data for model retraining represents an…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yaofei Duan , Yuhao Huang , Xin Yang , Luyi Han , Xinyu Xie , Zhiyuan Zhu , Ping He , Ka-Hou Chan , Ligang Cui , Sio-Kei Im , Dong Ni , Tao Tan