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Multi-modal medical image fusion is essential for the precise clinical diagnosis and surgical navigation since it can merge the complementary information in multi-modalities into a single image. The quality of the fused image depends on the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Xianming Gu , Lihui Wang , Zeyu Deng , Ying Cao , Xingyu Huang , Yue-min Zhu

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

With the availability of extraordinarily huge data sets, solving the problems of distributed statistical methodology and computing for such data sets has become increasingly crucial in the big data area. In this paper, we focus on the…

Machine Learning · Statistics 2023-10-24 Yue Chao , Lei Huang , Xuejun Ma

Many problems in control theory can be formulated as semidefinite programs (SDPs). For large-scale SDPs, it is important to exploit the inherent sparsity to improve the scalability. This paper develops efficient first-order methods to solve…

Optimization and Control · Mathematics 2020-01-13 Yang Zheng , Giovanni Fantuzzi , Antonis Papachristodoulou , Paul Goulart , Andrew Wynn

Accurate diagnosis of Alzheimer's disease (AD) requires effectively integrating multimodal data and clinical expertise. However, existing methods often struggle to fully utilize multimodal information and lack structured mechanisms to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Qiuhui Chen , Jintao Wang , Gang Wang , Yi Hong

This paper introduces the Bi-linear consensus Alternating Direction Method of Multipliers (Bi-cADMM), aimed at solving large-scale regularized Sparse Machine Learning (SML) problems defined over a network of computational nodes.…

Machine Learning · Computer Science 2024-06-27 Alireza Olama , Andreas Lundell , Jan Kronqvist , Elham Ahmadi , Eduardo Camponogara

The increasing complexity of deep learning recommendation models (DLRM) has led to a growing need for large-scale distributed systems that can efficiently train vast amounts of data. In DLRM, the sparse embedding table is a crucial…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-07 Xin Zhang , Quanyu Zhu , Liangbei Xu , Zain Huda , Wang Zhou , Jin Fang , Dennis van der Staay , Yuxi Hu , Jade Nie , Jiyan Yang , Chunzhi Yang

In recent years, the number of papers on Alzheimer's disease classification has increased dramatically, generating interesting methodological ideas on the use machine learning and feature extraction methods. However, practical impact is…

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where disease subtypes, for example, may differ with respect to underlying regression models, but sample sizes at the…

Highly distributed training of Deep Neural Networks (DNNs) on future compute platforms (offering 100 of TeraOps/s of computational capacity) is expected to be severely communication constrained. To overcome this limitation, new gradient…

Machine Learning · Computer Science 2017-12-08 Chia-Yu Chen , Jungwook Choi , Daniel Brand , Ankur Agrawal , Wei Zhang , Kailash Gopalakrishnan

Alzheimer's disease (AD) diagnosis requires integrating neuroimaging with heterogeneous clinical evidence and reasoning under established criteria, yet most multimodal models remain opaque and weakly guideline-aligned. We present…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Qiuhui Chen , Yushan Deng , Xuancheng Yao , Yi Hong

Modern data often take the form of a multiway array. However, most classification methods are designed for vectors, i.e., 1-way arrays. Distance weighted discrimination (DWD) is a popular high-dimensional classification method that has been…

Methodology · Statistics 2021-10-12 Bin Guo , Lynn E. Eberly , Pierre-Gilles Henry , Christophe Lenglet , Eric F. Lock

Multimodal emotion and intent recognition is essential for automated human-computer interaction, It aims to analyze users' speech, text, and visual information to predict their emotions or intent. One of the significant challenges is that…

Artificial Intelligence · Computer Science 2025-07-09 Wei Zhang , Juan Chen , Yanbo J. Wang , En Zhu , Xuan Yang , Yiduo Wang

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

Sparse penalized quantile regression provides an effective framework for variable selection and robust estimation in high-dimensional data analysis. When ex planatory variables are organized into groups, achieving sparsity both within and…

Computation · Statistics 2026-04-23 Huayan Kou , Yuwen Gu , Yi Lian , Rui Zhang , Jun Fan

Alzheimer's Disease (AD) and related dementia are a growing global health challenge due to the aging population. In this paper, we present ADMarker, the first end-to-end system that integrates multi-modal sensors and new federated learning…

Concept shift is a prevailing problem in natural tasks like medical image segmentation where samples usually come from different subpopulations with variant correlations between features and labels. One common type of concept shift in…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Yijun Dong , Yuege Xie , Rachel Ward

Image regression tasks for medical applications, such as bone mineral density (BMD) estimation and left-ventricular ejection fraction (LVEF) prediction, play an important role in computer-aided disease assessment. Most deep regression…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Weihang Dai , Xiaomeng Li , Wan Hang Keith Chiu , Michael D. Kuo , Kwang-Ting Cheng