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We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

Analysis of PDEs · Mathematics 2015-06-22 Donatella Donatelli , Konstantina Trivisa

We employ molecular dynamics simulations to investigate the domain morphology and growth kinetics of a vapor-liquid system embedded within a complex porous medium. By systematically varying the pore structure, we analyze the scaling…

Soft Condensed Matter · Physics 2025-06-12 Preethi M , Bhaskar Sen Gupta

We investigate the dynamics of a nonlinear model for tumor growth within a cellular medium. In this setting the "tumor" is viewed as a multiphase flow consisting of cancerous cells in either proliferating phase or quiescent phase and a…

Analysis of PDEs · Mathematics 2015-03-31 Donatella Donatelli , Konstantina Trivisa

A model for the aerobic and anaerobic growth of Escherichia coli (HB101 K12 pGLO) depending on the concentration of oxygen and DOC as substrate has been developed based on laboratory batch experiments. Using inverse modelling to obtain…

Cell Behavior · Quantitative Biology 2014-08-13 Pavel Hron , Daniel Jost , Peter Bastian , Claudia Gallert , Josef Winter , Olaf Ippisch

We study transport in a one-dimensional lattice system with two conserved quantities -- `volume' and energy. Considering a slowly evolving local equilibrium state that is slightly deviated from an underlying global equilibrium, we estimate…

Statistical Mechanics · Physics 2023-07-19 Anupam Kundu

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

We consider a class of tumor growth models under the combined effects of density-dependent pressure and cell multiplication, with a free boundary model as its singular limit when the pressure-density relationship becomes highly nonlinear.…

Numerical Analysis · Mathematics 2018-04-04 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

In this work a stochastic model of gaseous transfer in polymer/CNT nanocomposites is presented. The model takes into account interfacial areas, i.e. polymer depletion regions. The local regime of transport is controlled by the density of…

Materials Science · Physics 2023-11-09 Polina Kalashnikova , Ilia Kalashnikov , Konstantin Khromov

Biofilm growth changes many physical properties of porous media such as porosity, permeability and mass transport parameters. The growth depends on various environmental conditions, and in particular, on flow rates. Modeling the evolution…

We propose and analyze a one-dimensional multi-species cross-diffusion system with non-zero-flux boundary conditions on a moving domain, motivated by the mod- eling of a Physical Vapor Deposition process. Using the boundedness by entropy…

Analysis of PDEs · Mathematics 2017-09-22 Athmane Bakhta , Virginie Ehrlacher

We study a strongly interacting crowded system of self-propelled stiff filaments by event-driven Brownian dynamics simulations and an analytical theory to elucidate the intricate interplay of crowding and self-propulsion. We find a…

Soft Condensed Matter · Physics 2022-09-22 Suvendu Mandal , Christina Kurzthaler , Thomas Franosch , Hartmut Löwen

In this work, a two-dimensional time-fractional subdiffusion model is developed to investigate the underlying transport phenomena evolving in a binary medium comprised of two sub-domains occupied by homogeneous material. We utilise an…

Numerical Analysis · Mathematics 2021-02-05 Libo Feng , Ian Turner , Patrick Perre , Kevin Burrage

The crossover between dispersion patterns has been frequently observed in various systems. Inspired by the pathway-based kinetic model for E. coli chemotaxis that accounts for the intracellular adaptation process and noise, we propose a…

Analysis of PDEs · Mathematics 2025-01-07 Zhe Xue , Weiran Sun , Zhennan Zhou , Min Tang

We study a stochastic model of urban growth generating spatial distributions of population densities at an intermediate mesoscopic scale. The model is based on the antagonist interplay between the two opposite abstract processes of…

Physics and Society · Physics 2018-11-21 Juste Raimbault

We consider the homogenization of a model of reactive flows through periodic porous media involving a single solute which can be absorbed and desorbed on the pore boundaries. This is a system of two convection-diffusion equations, one in…

Analysis of PDEs · Mathematics 2014-12-30 Grégoire Allaire , Harsha Hutridurga

This paper presents a mathematical framework for modeling the dynamics of heterogeneous populations. Models describing local and non-local growth and transport processes, dependent on dynamically changing population structures, appear in a…

Analysis of PDEs · Mathematics 2023-10-02 Christian Düll , Piotr Gwiazda , Anna Marciniak-Czochra , Jakub Skrzeczkowski

We study molecular dynamics within populations of diffusively coupled cells under the assumption of fast diffusive exchange. As a technical tool, we propose conditions on boundedness and ultimate boundedness for systems with a singular…

Cell Behavior · Quantitative Biology 2012-12-19 Steffen Waldherr , Frank Allgöwer

Continuum mathematical models for collective cell motion normally involve reaction-diffusion equations, such as the Fisher-KPP equation, with a linear diffusion term to describe cell motility and a logistic term to describe cell…

Biological Physics · Physics 2019-07-24 Scott W McCue , Wang Jin , Timothy J Moroney , Kai-Yin Lo , Shih-En Chou , Matthew J Simpson

We consider the well-posedness of models involving age structure and non-linear diffusion. Such problems arise in the study of population dynamics. It is shown how diffusion and age boundary conditions can be treated that depend…

Analysis of PDEs · Mathematics 2008-10-31 Christoph Walker

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Soft Condensed Matter · Physics 2025-11-13 Nivedina A. Sarma , David A. King , Xuefei Wu , Brett A. Helms , Paul D. Ashby , Thomas P. Russell , Ahmad K. Omar