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Related papers: A complex network perspective on brain disease

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Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of…

Neurons and Cognition · Quantitative Biology 2011-07-19 Mikail Rubinov , Olaf Sporns

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…

This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…

Neurons and Cognition · Quantitative Biology 2018-09-18 Daniel Durstewitz , Quentin J. M. Huys , Georgia Koppe

Interactions between units in phyical, biological, technological, and social systems usually give rise to intrincate networks with non-trivial structure, which critically affects the dynamics and properties of the system. The focus of most…

Data Analysis, Statistics and Probability · Physics 2007-05-23 R. Guimera , M. Sales-Pardo , L. A. N. Amaral

The human brain is a complex network that supports mental function. The nascent field of network neuroscience applies tools from mathematics to neuroimaging data in the hopes of shedding light on cognitive function. A critical question…

Neurons and Cognition · Quantitative Biology 2017-04-26 John D. Medaglia , Perry Zurn , Walter Sinnott-Armstrong , Danielle S. Bassett

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

Recent advances in network science, applied to \textit{in vivo} brain recordings, have paved the way for better understanding of the structure and function of the brain. However, despite its obvious usefulness in neuroscience, traditional…

Neurons and Cognition · Quantitative Biology 2025-02-03 Vesna Vuksanovic

Functional networks, i.e. networks representing dynamic relationships between the components of a complex system, have been instrumental for our understanding of, among others, the human brain. Due to limited data availability, the…

Physics and Society · Physics 2015-06-24 Massimiliano Zanin

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

This report discusses the application of neural networks (NNs) as small segments of the brain. The networks representing the biological connectome are altered both spatially and temporally. The degradation techniques applied here are…

Neurons and Cognition · Quantitative Biology 2020-08-04 Jacob Adamczyk

Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This…

Physics and Society · Physics 2025-04-16 Rui Tang , Ziyun Yong , Shuyu Jiang , Xingshu Chen , Yaofang Liu , Yi-Cheng Zhang , Gui-Quan Sun , Wei Wang

For the study of functional aspects of the brain network. This paper is a study on the hypergraph representation, based on the functional regions of the brain network. A new parameter that can measure how many multifunctioning regions each…

Neurons and Cognition · Quantitative Biology 2023-12-20 Anagha P , Selvakumar R

Understanding brain connectivity in a network-theoretic context has shown much promise in recent years. This type of analysis identifies brain organisational principles, bringing a new perspective to neuroscience. At the same time, large…

Neural and Evolutionary Computing · Computer Science 2016-11-28 Sarah Parisot , Jonathan Passerat-Palmbach , Markus D. Schirmer , Boris Gutman

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…

Neurons and Cognition · Quantitative Biology 2022-09-13 Anca Radulescu , Johan Nakuci , Simone Evans , Sarah Muldoon

For complex life to evolve, a sophisticated nervous system for handling its complexities was fundamental. The demand resulted in the emergence of brain's computational facility, the neuronal network. This facet of the brain is attested…

Neurons and Cognition · Quantitative Biology 2019-09-16 Jahan N. Schad

Sustainable research on computational models of neuronal networks requires published models to be understandable, reproducible, and extendable. Missing details or ambiguities about mathematical concepts and assumptions, algorithmic…

Graph theoretical approach has proved an effective tool to understand, characterize and quantify the complex brain network. However, much less attention has been paid to methods that quantitatively compare two graphs, a crucial issue in the…

Neurons and Cognition · Quantitative Biology 2019-08-29 Ahmad Mheich , Fabrice Wendling , Mahmoud Hassan

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

We define a notion of complexity, which quantifies the nonlinearity of the computation of a neural network, as well as a complementary measure of the effective dimension of feature representations. We investigate these observables both for…

Machine Learning · Computer Science 2021-03-18 Romuald A. Janik , Przemek Witaszczyk