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We present Bayesian Diffusion Models (BDM), a prediction algorithm that performs effective Bayesian inference by tightly coupling the top-down (prior) information with the bottom-up (data-driven) procedure via joint diffusion processes. We…
Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…
As a class of generative artificial intelligence frameworks inspired by statistical physics, diffusion models have shown extraordinary performance in synthesizing complicated data distributions through a denoising process gradually guided…
Recent studies on deepfake detection have achieved promising results when training and testing faces are from the same dataset. However, their results severely degrade when confronted with forged samples that the model has not yet seen…
In clinical practice, full imaging is not always feasible, often due to complex acquisition protocols, stringent privacy regulations, or specific clinical needs. However, missing MR modalities pose significant challenges for tasks like…
Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…
Recent advances in bioinformatics have made high-throughput microbiome data widely available, and new statistical tools are required to maximize the information gained from these data. For example, analysis of high-dimensional microbiome…
Early prediction of Mild Cognitive Impairment (MCI) conversion is hampered by a trade-off between immediacy--making fast predictions from a single baseline sMRI--and accuracy--leveraging longitudinal scans to capture disease progression. We…
The emergence of generative AI and controllable diffusion has made image-to-image synthesis increasingly practical and efficient. However, when input images exhibit low entropy and sparse, the inherent characteristics of diffusion models…
Early detection through imaging and accurate diagnosis is crucial in mitigating the high mortality rate associated with breast cancer. However, locating tumors from low-resolution and high-noise medical images is extremely challenging.…
The Cambrian explosion of easily accessible pre-trained diffusion models suggests a demand for methods that combine multiple different pre-trained diffusion models without incurring the significant computational burden of re-training a…
Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…
Diffusion Models have become a cornerstone of modern generative AI for their exceptional generation quality and controllability. However, their inherent \textit{multi-step iterations} and \textit{complex backbone networks} lead to…
Diffusion MRI (dMRI) is an important neuroimaging technique with high acquisition costs. Deep learning approaches have been used to enhance dMRI and predict diffusion biomarkers through undersampled dMRI. To generate more comprehensive raw…
Multivariate time series imputation is fundamental in applications such as healthcare, traffic forecasting, and biological modeling, where sensor failures and irregular sampling lead to pervasive missing values. However, existing…
Data-driven dynamics prediction often fails under environmental shifts, while traditional fine-tuning remains computationally prohibitive for hardware-constrained or data-scarce applications. We propose DynaDiff, a generative meta-learning…
Predicting counterfactual outcomes in longitudinal data, where sequential treatment decisions heavily depend on evolving patient states, is critical yet notoriously challenging due to complex time-dependent confounding and inadequate…
The implementation of diffusion-based pansharpening task is predominantly constrained by its slow inference speed, which results from numerous sampling steps. Despite the existing techniques aiming to accelerate sampling, they often…
Modern cancer genomics datasets involve widely varying sizes and scales, measurement variables, and correlation structures. A fundamental analytical goal in these high-throughput studies is the development of general statistical techniques…
Diffusion models have proven to be highly effective in generating high-quality images. However, adapting large pre-trained diffusion models to new domains remains an open challenge, which is critical for real-world applications. This paper…