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In areas infested with Aedes aegypti mosquitoes it may be possible to control dengue, and some other vector-borne diseases, by introducing Wolbachia-infected mosquitoes into the wildtype population. Thus far, empirical and theoretical…

Populations and Evolution · Quantitative Biology 2025-02-19 Abby Barlow , Sarah Penington , Ben Adams

Arboviral diseases remain a major public health concern, particularly in tropical and subtropical regions where mosquito populations thrive. One promising strategy to curb transmission is the release of Aedes aegypti mosquitoes infected…

Populations and Evolution · Quantitative Biology 2025-03-18 Daniela Florez , Ricardo Cortez , James M. Hyman , Zhuolin Qu

Wolbachia is a naturally occurring bacterium that can infect Aedes mosquitoes and reduce the transmission of mosquito-borne diseases, including dengue fever, Zika, and chikungunya. Field trials have been conducted worldwide to suppress…

Populations and Evolution · Quantitative Biology 2024-12-02 Zhuolin Qu , Tong Wu

In this article, we consider a simplified model of time dynamics for a mosquito population subject to the artificial introduction of {\itshape Wolbachia}-infected mosquitoes, in order to fight arboviruses transmission.Indeed, it has been…

Analysis of PDEs · Mathematics 2019-09-09 Luís Almeida , Yannick Privat , Martin Strugarek , Nicolas Vauchelet

The release of Wolbachia-infected mosquitoes is a promising strategy for controlling Aedes aegypti populations, but exposure to high temperatures can induce temporary infection loss and compromise long-term persistence. In this work, we…

Populations and Evolution · Quantitative Biology 2026-02-10 Jéssica C. S. Alves , Christian E. Schaerer , Cláudia P. Ferreira

Wolbachia is a genus of endosymbiotic bacteria that can infect mosquitoes and reduce their ability to transmit dengue virus. Although the bacterium is transmitted vertically from infected mothers to their offspring, it can be difficult to…

Populations and Evolution · Quantitative Biology 2015-10-06 Ling Xue , Carrie A. Manore , Panpim Thongsripong , James M. Hyman

In this paper, we propose a simplified bidimensional Wolbachia infestation model in a population of Aedes aegypti mosquitoes, preserving the main features associated with the biology of this species that can be found in higher-dimensional…

Dynamical Systems · Mathematics 2020-11-23 Diego Vicencio , Olga Vasilieva , Pedro Gajardo

This work is devoted to the mathematical study of an optimization problem regarding control strategies of mosquito population in a heterogeneous environment. Mosquitoes are well-known vectors of diseases. For some diseases, such as dengue,…

Optimization and Control · Mathematics 2025-03-11 Luis Almeida , Jesús Bellver Arnau , Gwenaël Peltier , Nicolas Vauchelet

Wolbachia is a natural bacterium that can infect mosquitoes and reduce their ability to transmit mosquito-borne diseases, such as dengue fever, Zika, and chikungunya. Field trials and modeling studies have shown that the fraction of…

Populations and Evolution · Quantitative Biology 2021-08-25 Zhuolin Qu , Tong Wu , James Mac Hyman

The control of the spread of dengue fever by introduction of the intracellular parasitic bacterium Wolbachia in populations of the vector Aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of…

Quantitative Methods · Quantitative Biology 2020-10-02 Pierre-Alexandre J. Bliman , M. Soledad Aronna , Flávio C. Coelho , Moacyr A. H. B. da Silva

Dengue, which affects millions of people each year, is one of the most common diseases transmitted by infected \textit{Aedes aegypti} mosquitoes. In the Philippines, the annual economic cost of dengue infections is estimated at around PHP…

Optimization and Control · Mathematics 2026-01-19 Kyrho Corum , Renier Mendoza , Victoria May P. Mendoza , Arrianne Crystal Velasco

An ordinary differential model is proposed to understand the role of egg quiescence on the efficacy of releasing Wolbachia-infected mosquitoes to control arbovirus transmission. The model admits up to five equilibrium points and four…

Populations and Evolution · Quantitative Biology 2025-07-17 Luís E. S. Lopes , Cláudia P. Ferreira

We develop and analyze an ordinary differential equation model to assess the potential effectiveness of infecting mosquitoes with the Wolbachia bacteria to control the ongoing mosquito-borne epidemics, such as dengue fever, chikungunya, and…

Populations and Evolution · Quantitative Biology 2020-08-14 Zhuolin Qu , Ling Xue , James M. Hyman

In a study conducted in Singapore, a country prone to dengue outbreaks due to its climate and urban population, researchers examined the effectiveness of releasing male Aedes aegypti mosquitoes infected with Wolbachia (wAlbB strain) to…

The introduction of Wolbachia-carrying mosquitoes into the population has recently been proposed as an alternative strategy against dengue. Although laboratory experiments have shown that the Wolbachia bacterium can reduce the levels of…

Populations and Evolution · Quantitative Biology 2017-11-13 Meksianis Z. Ndii

This paper proposes two realistic and biologically viable methods for Wolbachia-based biocontrol of Aedes aegypti mosquitoes, assuming imperfect maternal transmission of the Wolbachia bacterium, incomplete cytoplasmic incompatibility, and…

Artificial releases of Wolbachia-infected Aedes mosquitoes have been under study in the past years for fighting vector-borne diseases such as dengue, chikungunya and zika. Several strains of this bacterium cause cytoplasmic incompatibility…

Analysis of PDEs · Mathematics 2017-07-31 Martin Strugarek , Nicolas Vauchelet , Jorge Zubelli

Releasing sterile Wolbachia-infected mosquitoes to invade wild mosquito population is a method of mosquito control. In this paper, a stochastic mosquito population model with Wolbachia invasion perturbed by environmental fluctuation is…

Dynamical Systems · Mathematics 2023-08-04 Yuanping Cui , Xiaoyue Li , Xuerong Mao , Hongfu Yang

Wolbachia infection in Anopheles albimanus mosquitoes can render mosquitoes less capable of spreading malaria. We develop and analyze an ordinary differential equation model to evaluate the effectiveness of Wolbachia-based vector control…

Populations and Evolution · Quantitative Biology 2023-03-10 Daniela Florez , Alyssa Young , Kerlly J. Bernabe , James M. Hyman , Zhuolin Qu

Arboviral infections, especially dengue, continue to cause significant health burden in their endemic regions. One of the strategies to tackle these infections is to replace the main vector agent, Ae. aegypti, with the ones incapable of…

Populations and Evolution · Quantitative Biology 2019-10-22 Adeshina I. Adekunle , Michael T. Meehan , Emma S. McBryde
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