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Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Vision-language models (VLMs) have achieved impressive progress in natural image reasoning, yet their potential in medical imaging remains underexplored. Medical vision-language tasks demand precise understanding and clinically coherent…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yuxiang Lai , Jike Zhong , Ming Li , Shitian Zhao , Yuheng Li , Konstantinos Psounis , Xiaofeng Yang

Developing 3D vision-language models with robust clinical reasoning remains a challenge due to the inherent complexity of volumetric medical imaging, the tendency of models to overfit superficial report patterns, and the lack of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Haoran Lai , Zihang Jiang , Kun Zhang , Qingsong Yao , Rongsheng Wang , Zhiyang He , Xiaodong Tao , Wei Wei , Shaohua Kevin Zhou

Reinforcement learning from verifiable rewards (RLVR) has recently gained attention for its ability to elicit self-evolved reasoning capabilitie from base language models without explicit reasoning supervisions, as demonstrated by…

Computation and Language · Computer Science 2025-02-28 Sheng Zhang , Qianchu Liu , Guanghui Qin , Tristan Naumann , Hoifung Poon

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

Machine Learning · Computer Science 2026-04-14 Haolin Li , Shuyang Jiang , Ruipeng Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Recent advances in reinforcement learning with verifiable, rule-based rewards have greatly enhanced the reasoning capabilities and out-of-distribution generalization of VLMs/LLMs, obviating the need for manually crafted reasoning chains.…

Artificial Intelligence · Computer Science 2025-05-27 Shaohao Rui , Kaitao Chen , Weijie Ma , Xiaosong Wang

The growing integration of vision-language models (VLMs) in medical applications offers promising support for diagnostic reasoning. However, current medical VLMs often face limitations in generalization, transparency, and computational…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Tan-Hanh Pham , Chris Ngo

Retrieval-Augmented Generation (RAG) integrates external knowledge with Large Language Models (LLMs) to enhance factual correctness and mitigate hallucination. However, dense retrievers often become the bottleneck of RAG systems due to…

Computation and Language · Computer Science 2025-10-27 Yuan Li , Qi Luo , Xiaonan Li , Bufan Li , Qinyuan Cheng , Bo Wang , Yining Zheng , Yuxin Wang , Zhangyue Yin , Xipeng Qiu

Reasoning is a critical frontier for advancing medical image analysis, where transparency and trustworthiness play a central role in both clinician trust and regulatory approval. Although Medical Visual Language Models (VLMs) show promise…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Jiazhen Pan , Che Liu , Junde Wu , Fenglin Liu , Jiayuan Zhu , Hongwei Bran Li , Chen Chen , Cheng Ouyang , Daniel Rueckert

Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

Computation and Language · Computer Science 2025-06-23 Xiaotian Zhang , Yuan Wang , Zhaopeng Feng , Ruizhe Chen , Zhijie Zhou , Yan Zhang , Hongxia Xu , Jian Wu , Zuozhu Liu

Efficiently acquiring external knowledge and up-to-date information is essential for effective reasoning and text generation in large language models (LLMs). Prompting advanced LLMs with reasoning capabilities to use search engines during…

Computation and Language · Computer Science 2025-08-07 Bowen Jin , Hansi Zeng , Zhenrui Yue , Jinsung Yoon , Sercan Arik , Dong Wang , Hamed Zamani , Jiawei Han

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Medical language models face critical barriers to real-world clinical reasoning applications. However, mainstream efforts, which fall short in task coverage, lack fine-grained supervision for intermediate reasoning steps, and rely on…

Computation and Language · Computer Science 2025-11-26 Shuyang Jiang , Yusheng Liao , Zhe Chen , Ya Zhang , Yanfeng Wang , Yu Wang

Large language models (LLMs) have notably progressed in multi-step and long-chain reasoning. However, extending their reasoning capabilities to encompass deep interactions with search remains a non-trivial challenge, as models often fail to…

Computation and Language · Computer Science 2025-06-05 Qingfei Zhao , Ruobing Wang , Dingling Xu , Daren Zha , Limin Liu

Large Language Models (LLMs) have demonstrated a remarkable potential in medical knowledge acquisition and question-answering. However, LLMs can potentially hallucinate and yield factually incorrect outcomes, even with domain-specific…

Computation and Language · Computer Science 2024-07-01 Junda Wang , Zhichao Yang , Zonghai Yao , Hong Yu

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

Retrieval-Augmented Generation (RAG) effectively enhances Large Language Models (LLMs) by incorporating retrieved external knowledge into the generation process. Reasoning models improve LLM performance in multi-hop QA tasks, which require…

Computation and Language · Computer Science 2026-01-21 Guo Chen , Junjie Huang , Huaijin Xie , Fei Sun , Tao Jia

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao
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