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There has been growing interest in developing optimal individualized treatment rules (ITRs) in various fields, such as precision medicine, business decision-making, and social welfare distribution. The application of ITRs within a societal…

Methodology · Statistics 2025-04-29 Wenhai Cui , Wen Su , Xiaodong Yan , Donglin Zeng , Xingqiu Zhao

We develop an algorithm to train individually fair learning-to-rank (LTR) models. The proposed approach ensures items from minority groups appear alongside similar items from majority groups. This notion of fair ranking is based on the…

Machine Learning · Statistics 2021-03-23 Amanda Bower , Hamid Eftekhari , Mikhail Yurochkin , Yuekai Sun

Recent development in the data-driven decision science has seen great advances in individualized decision making. Given data with individual covariates, treatment assignments and outcomes, policy makers best individualized treatment rule…

Machine Learning · Statistics 2020-06-29 Weibin Mo , Zhengling Qi , Yufeng Liu

An individualized treatment rule (ITR) is a decision rule that recommends treatments for patients based on their individual feature variables. In many practices, the ideal ITR for the primary outcome is also expected to cause minimal harm…

Methodology · Statistics 2024-05-24 Daiqi Gao , Yuanjia Wang , Donglin Zeng

An individualized treatment regime (ITR) is a decision rule that assigns treatments based on patients' characteristics. The value function of an ITR is the expected outcome in a counterfactual world had this ITR been implemented. Recently,…

Methodology · Statistics 2023-01-16 Pan Zhao , Julie Josse , Shu Yang

To study discrimination in automated decision-making systems, scholars have proposed several definitions of fairness, each expressing a different fair ideal. These definitions require practitioners to make complex decisions regarding which…

Computers and Society · Computer Science 2021-02-23 Kweku Kwegyir-Aggrey , Rebecca Santorella , Sarah M. Brown

To promote precision medicine, individualized treatment regimes (ITRs) are crucial for optimizing the expected clinical outcome based on patient-specific characteristics. However, existing ITR research has primarily focused on scenarios…

Methodology · Statistics 2024-02-20 Chang Wang , Lu Wang

Individualized decision rules (IDRs) have become increasingly prevalent in societal applications such as personalized marketing, healthcare, and public policy design. However, a critical ethical concern arises from the potential…

Machine Learning · Statistics 2026-03-06 Wenhai Cui , Wen Su , Donglin Zeng , Xingqiu Zhao

Individualized treatment effect lies at the heart of precision medicine. Interpretable individualized treatment rules (ITRs) are desirable for clinicians or policymakers due to their intuitive appeal and transparency. The gold-standard…

Methodology · Statistics 2021-08-20 Lili Wu , Shu Yang

Explicit and implicit bias clouds human judgement, leading to discriminatory treatment of minority groups. A fundamental goal of algorithmic fairness is to avoid the pitfalls in human judgement by learning policies that improve the overall…

Machine Learning · Computer Science 2020-11-02 Yuzi He , Keith Burghardt , Siyi Guo , Kristina Lerman

Statistical algorithms are usually helping in making decisions in many aspects of our lives. But, how do we know if these algorithms are biased and commit unfair discrimination of a particular group of people, typically a minority?…

Statistics Theory · Mathematics 2018-07-19 Eustasio del Barrio , Fabrice Gamboa , Paula Gordaliza , Jean-Michel Loubes

Estimating individualized treatment rules (ITRs) is crucial for tailoring interventions in precision medicine. Typical ITR estimation methods rely on conditional average treatment effects (CATEs) to guide treatment assignments. However,…

Methodology · Statistics 2025-10-20 Peng Wu , Qing Jiang , Shanshan Luo , Zhi Geng

We develop a mathematical framework to define an optimal individualized treatment rule (ITR) within the context of prioritized outcomes in a randomized controlled trial. Our optimality criterion is based on the framework of generalized…

Methodology · Statistics 2025-06-17 François Petit , Gérard Biau , Raphaël Porcher

Randomized controlled trials typically analyze the effectiveness of treatments with the goal of making treatment recommendations for patient subgroups. With the advance of electronic health records, a great variety of data has been…

Machine Learning · Computer Science 2021-03-31 Zhiliang Wu , Yinchong Yang , Yunpu Ma , Yushan Liu , Rui Zhao , Michael Moor , Volker Tresp

Individualized treatment rules (ITR) can improve health outcomes by recognizing that patients may respond differently to treatment and assigning therapy with the most desirable predicted outcome for each individual. Flexible and efficient…

Methodology · Statistics 2017-09-25 Brent R. Logan , Rodney Sparapani , Robert E. McCulloch , Purushottam W. Laud

Data-driven individualized decision making has recently received increasing research interests. Most existing methods rely on the assumption of no unmeasured confounding, which unfortunately cannot be ensured in practice especially in…

Methodology · Statistics 2022-12-26 Zhengling Qi , Rui Miao , Xiaoke Zhang

An individualized treatment rule (ITR) is a decision rule that aims to improve individual patients health outcomes by recommending optimal treatments according to patients specific information. In observational studies, collected data may…

Methodology · Statistics 2023-10-03 Zeyu Bian , Erica EM Moodie , Susan M Shortreed , Sylvie D Lambert , Sahir Bhatnagar

Integrative analysis of multiple datasets for estimating optimal individualized treatment rules (ITRs) can enhance decision efficiency. A central challenge is posterior shift, wherein the conditional distribution of potential outcomes given…

Machine Learning · Statistics 2026-03-09 Wenhai Cui , Wen Su , Xingqiu Zhao

In past work on fairness in machine learning, the focus has been on forcing the prediction of classifiers to have similar statistical properties for people of different demographics. To reduce the violation of these properties, fairness…

Machine Learning · Computer Science 2022-12-02 Maarten Buyl , Tijl De Bie

State-of-the-art order dispatching algorithms for ridesharing batch passenger requests and allocate them to a fleet of vehicles in a centralized manner, optimizing over the estimated values of each passenger-vehicle matching using integer…

Artificial Intelligence · Computer Science 2023-03-28 Ashwin Kumar , Yevgeniy Vorobeychik , William Yeoh
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