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The field of medical image segmentation is challenged by domain generalization (DG) due to domain shifts in clinical datasets. The DG challenge is exacerbated by the scarcity of medical data and privacy concerns. Traditional single-source…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Qiang Qiao , Wenyu Wang , Meixia Qu , Kun Su , Bin Jiang , Qiang Guo

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

Purpose: Applying pre-trained medical deep learning segmentation models on out-of-domain images often yields predictions of insufficient quality. In this study, we propose to use a powerful generalizing descriptor along with augmentation to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Christian Weihsbach , Christian N. Kruse , Alexander Bigalke , Mattias P. Heinrich

An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yanwu Xu , Shaoan Xie , Maxwell Reynolds , Matthew Ragoza , Mingming Gong , Kayhan Batmanghelich

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

Medical imaging is a cornerstone of modern healthcare, driving advancements in diagnosis, treatment planning, and patient care. Among its various tasks, segmentation remains one of the most challenging problem due to factors such as data…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Fares Bougourzi , Abdenour Hadid

Medical data often exhibits distribution shifts, which cause test-time performance degradation for deep learning models trained using standard supervised learning pipelines. This challenge is addressed in the field of Domain Generalization…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Aleksandr Matsun , Numan Saeed , Fadillah Adamsyah Maani , Mohammad Yaqub

Domain generalization remains a critical challenge in medical imaging, where models trained on single sources often fail under real-world distribution shifts. We propose KG-DG, a neuro-symbolic framework for diabetic retinopathy (DR)…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

Medical imaging datasets usually exhibit domain shift due to the variations of scanner vendors, imaging protocols, etc. This raises the concern about the generalization capacity of machine learning models. Domain generalization (DG), which…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Chenxin Li , Qi Qi , Xinghao Ding , Yue Huang , Dong Liang , Yizhou Yu

Automatic organ segmentation is an important yet challenging problem for medical image analysis. The pancreas is an abdominal organ with very high anatomical variability. This inhibits previous segmentation methods from achieving high…

Computer Vision and Pattern Recognition · Computer Science 2015-06-23 Holger R. Roth , Le Lu , Amal Farag , Hoo-Chang Shin , Jiamin Liu , Evrim Turkbey , Ronald M. Summers

Computer-aided detection systems based on deep learning have shown great potential in breast cancer detection. However, the lack of domain generalization of artificial neural networks is an important obstacle to their deployment in changing…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Lidia Garrucho , Kaisar Kushibar , Socayna Jouide , Oliver Diaz , Laura Igual , Karim Lekadir

The generalization of deep neural networks to unknown domains is a major challenge despite their tremendous progress in recent years. For this reason, the dynamic area of domain generalization (DG) has emerged. In contrast to unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Manuel Schwonberg , Hanno Gottschalk

Accurate segmentation of lesions in pancreatic endoscopic ultrasound (EUS) images is crucial for effective diagnosis and treatment. However, the collection of enough crisp EUS images for effective diagnosis is arduous. Recently, domain…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 ZhiChao Yan , Hui Xue , Yi Zhu , Bin Xiao , Hao Yuan

Diabetic Retinopathy (DR) constitutes 5% of global blindness cases. While numerous deep learning approaches have sought to enhance traditional DR grading methods, they often falter when confronted with new out-of-distribution data thereby…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Sharon Chokuwa , Muhammad Haris Khan

Efficient medical image segmentation aims to provide accurate pixel-wise predictions for medical images with a lightweight implementation framework. However, lightweight frameworks generally fail to achieve superior performance and suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Xingqun Qi , Zhuojie Wu , Min Ren , Muyi Sun , Caifeng Shan , Zhenan Sun

Domain shifts in medical image segmentation, particularly when data comes from different centers, pose significant challenges. Intra-center variability, such as differences in scanner models or imaging protocols, can cause domain shifts as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jin Hong , Bo Liu

Machine learning algorithms have revolutionized different fields, including natural language processing, computer vision, signal processing, and medical data processing. Despite the excellent capabilities of machine learning algorithms in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Gita Sarafraz , Armin Behnamnia , Mehran Hosseinzadeh , Ali Balapour , Amin Meghrazi , Hamid R. Rabiee

Domain generalization(DG) endeavors to develop robust models that possess strong generalizability while preserving excellent discriminability. Nonetheless, pivotal DG techniques tend to improve the feature generalizability by learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Shaocong Long , Qianyu Zhou , Chenhao Ying , Lizhuang Ma , Yuan Luo

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert