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Computable phenotypes are used to characterize patients and identify outcomes in studies conducted using healthcare claims and electronic health record data. Chart review studies establish reference labels against which computable…

Applications · Statistics 2025-03-11 Georg Hahn , Sebastian Schneeweiss , Shirley Wang

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Context: To reduce manual effort of extracting test cases from natural-language requirements, many approaches based on Natural Language Processing (NLP) have been proposed in the literature. Given the large amount of approaches in this…

Software Engineering · Computer Science 2020-03-25 Vahid Garousi , Sara Bauer , Michael Felderer

Clinical patient notes are critical for documenting patient interactions, diagnoses, and treatment plans in medical practice. Ensuring accurate evaluation of these notes is essential for medical education and certification. However, manual…

Computation and Language · Computer Science 2024-01-25 Jingyu Xu , Yifeng Jiang , Bin Yuan , Shulin Li , Tianbo Song

Accurate ground truth estimation in medical screening programs often relies on coalitions of experts and peer second opinions. Algorithms that efficiently aggregate noisy annotations can enhance screening workflows, particularly when data…

Machine Learning · Computer Science 2025-10-07 Tim Bary , Tiffanie Godelaine , Axel Abels , Benoît Macq

This thesis addresses challenges related to data and parameter efficiency in neural language models, with a focus on representation analysis and the introduction of new optimization techniques. The first part examines the properties and…

Computation and Language · Computer Science 2025-07-17 Josip Jukić

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by…

Computation and Language · Computer Science 2025-02-05 Muhammad Bilal , Ameer Hamza , Nadia Malik

Objectives: The vast and complex nature of human genomic sequencing data presents challenges for effective analysis. This review aims to investigate the application of Natural Language Processing (NLP) techniques, particularly Large…

Genomics · Quantitative Biology 2025-02-28 Shuyan Cheng , Yishu Wei , Yiliang Zhou , Zihan Xu , Drew N Wright , Jinze Liu , Yifan Peng

In the United States, 25% or greater than 200 billion dollars of hospital spending accounts for administrative costs that involve services for medical coding and billing. With the increasing number of patient records, manual assignment of…

Computation and Language · Computer Science 2020-03-18 A. K. Bhavani Singh , Mounika Guntu , Ananth Reddy Bhimireddy , Judy W. Gichoya , Saptarshi Purkayastha

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Chart summarization, which focuses on extracting key information from charts and interpreting it in natural language, is crucial for generating and delivering insights through effective and accessible data analysis. Traditional methods for…

Multimedia · Computer Science 2024-12-31 Peixin Xu , Yujuan Ding , Wenqi Fan

Data annotated by humans is a source of knowledge by describing the peculiarities of the problem and therefore fueling the decision process of the trained model. Unfortunately, the annotation process for subjective natural language…

Computation and Language · Computer Science 2023-12-14 Kamil Kanclerz , Julita Bielaniewicz , Marcin Gruza , Jan Kocon , Stanisław Woźniak , Przemysław Kazienko

Cardiovascular diseases are becoming increasingly prevalent in modern society, with a profound impact on global health and well-being. These Cardiovascular disorders are complex and multifactorial, influenced by genetic predispositions,…

Computation and Language · Computer Science 2025-10-23 Kailai Yang , Yan Leng , Xin Zhang , Tianlin Zhang , Paul Thompson , Bernard Keavney , Maciej Tomaszewski , Sophia Ananiadou

Clinical natural language processing (NLP) is increasingly in demand in both clinical research and operational practice. However, most of the state-of-the-art solutions are transformers-based and require high computational resources,…

Computation and Language · Computer Science 2025-04-18 Jianlin Shi , Qiwei Gan , Elizabeth Hanchrow , Annie Bowles , John Stanley , Adam P. Bress , Jordana B. Cohen , Patrick R. Alba

With the growing number of submitted scientific papers, there is an increasing demand for systems that can assist reviewers in evaluating research claims. Experimental results are a core component of scientific work, often presented in…

Computation and Language · Computer Science 2025-11-14 Xanh Ho , Yun-Ang Wu , Sunisth Kumar , Florian Boudin , Atsuhiro Takasu , Akiko Aizawa

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin

Context: Various approaches aim to support program comprehension by automatically detecting algorithms in source code. However, no empirical evaluations of their helpfulness have been performed. Objective: To empirically evaluate how…

Software Engineering · Computer Science 2025-04-29 Denis Neumüller , Alexander Raschke , Matthias Tichy
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