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Phase separation can drive spatial organization of multicomponent mixtures. For instance in developing animal embryos, effective phase separation descriptions have been used to account for the spatial organization of different tissue types.…

Soft Condensed Matter · Physics 2023-01-18 Simon Gsell , Matthias Merkel

Phase separation plays an role in determining the self-assembly of biological and soft-matter systems. In biological systems, liquid-liquid phase separation inside a cell leads to the formation of various macromolecular aggregates. The…

Soft Condensed Matter · Physics 2024-03-26 Tanmay Biswas , Gerhard Kahl , Gaurav P. Shrivastav

Liquid-liquid phase separation, whereby two liquids spontaneously demix, is ubiquitous in industrial, environmental, and biological processes. While isotropic fluids are known to condense into spherical droplets in the binodal region, these…

These lecture notes describe a basic theory of chemically active droplets, which are droplets kept away from equilibrium by driven chemical reactions. The notes assume a basic familiarity with equilibrium thermodynamics of phase separation,…

Soft Condensed Matter · Physics 2024-07-16 David Zwicker

Much work has been devoted to analysing thermodynamic models for solid dispersions with a view to identifying regions in the phase diagram where amorphous phase separation or drug recrystallization can occur. However, detailed partial…

Soft Condensed Matter · Physics 2020-06-26 Martin Meere , Giuseppe Pontrelli , Sean McGinty

The properties of the interface in a phase-separated solution of polymers with different degrees of polymerization and Kuhn segment lengths are calculated. The starting point is the planar interface, the profile of which is calculated in…

Soft Condensed Matter · Physics 2015-06-15 R. H. Tromp , E. M. Blokhuis

We present a generalized theory for studying phase separation in blends of polymers containing dipoles on their backbone. The theory is used to construct co-existence curves and to study the effects of dipolar interactions on interfacial…

Soft Condensed Matter · Physics 2014-11-04 Rajeev Kumar , Bobby G. Sumpter , M. Muthukumar

A novel supersolid phase is predicted for an ensemble of Rydberg atoms in the dipole-blockade regime, interacting via a repulsive dipolar potential "softened" at short distances. Using exact numerical techniques, we study the low…

Quantum Gases · Physics 2010-09-23 F. Cinti , P. Jain , M. Boninsegni , A. Micheli , P. Zoller , G. Pupillo

We perform simulations of a system containing simple model proteins and a polymer representing chromatin. We study the interplay between protein-protein and protein-chromatin interactions, and the resulting condensates which arise due to…

Soft Condensed Matter · Physics 2022-07-20 Marco Ancona , Chris A. Brackley

Evaporation alters the molecular interactions and leads to phase separation within the evaporating liquid. The question of whether evaporation could lead to specific phase separation at the liquid interface and eventually to the formation…

Soft Condensed Matter · Physics 2024-08-27 Vahid Nasirimarekani

A phenomenological mean-field theory is used to investigate the properties of solvent-diluted di-block copolymers (BCP), in which the two BCP components (A and B) form a variety of phases that are diluted by a solvent (S). Using this…

Soft Condensed Matter · Physics 2014-04-22 Shai Cohen , David Andelman

The phase separation of a simple binary mixture of incompatible linear polymers in solution is investigated using an extension of the sedimentation equilibrium method, whereby the osmotic pressure of the mixture is extracted from the…

Soft Condensed Matter · Physics 2009-09-29 Chris I. Addison , Pierre-Arnaud Artola , Jean-Pierre Hansen , Ard A. Louis

The formation of (bio)molecular condensates via liquid-liquid phase separation in cells has received increasing attention, as these coacervates play important functional and regulatory roles within biological systems. However, the majority…

Soft Condensed Matter · Physics 2022-11-24 Arash Nikoubashman , Miho Yanagisawa

The pressure-temperature phase diagram of a one-component system, with particles interacting through a spherically symmetric pair potential is studied. It is shown that if the pair potential allows for a discontinuous reduction of the…

Statistical Mechanics · Physics 2008-02-03 E. A. Jagla

Insoluble surfactant monolayers at the air/water interface undergo a phase transition from a high-temperature homogeneous state to a low-temperature demixed state, where dilute and dense phases coexist. Alternatively, the transition from a…

Soft Condensed Matter · Physics 2007-05-23 X. Chatellier , D. Andelman

Biomolecular condensates form on timescales of seconds in cells upon environmental or compositional changes. Condensate formation is thus argued to act as a mechanism for sensing such changes and quickly initiating downstream processes,…

Subcellular Processes · Quantitative Biology 2025-12-09 Henry Alston , Mason Rouches , Arvind Murugan , Aleksandra M. Walczak , Thierry Mora

The formation of small droplets and bubbles in turbulent flows is a crucial process in geophysics and engineering, whose underlying physical mechanism remains a puzzle. In this letter, we address this problem by means of high-resolution…

A diffuse-interface model for microstructure with an arbitrary number of components and phases was developed from basic thermodynamic and kinetic principles and formalized within a variational framework. The model includes a composition…

Materials Science · Physics 2011-07-28 Daniel A. Cogswell , W. Craig Carter

Chemically driven fluids can demix to form condensed droplets that exhibit phase behaviors not observed at equilibrium. In particular, nonequilibrium interfacial properties can emerge when the chemical reactions are driven differentially…

Soft Condensed Matter · Physics 2023-11-20 Yongick Cho , William M. Jacobs

Aerobreakup of fluid droplets under the influence of impulsively generated high-speed gas flow using an open-ended shock tube is studied using experiments and numerical simulations. Breakup of mm-sized droplets at high Weber number was…

Fluid Dynamics · Physics 2022-06-24 James Leung , Mohana Gurunadhan , Shyam Menon