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Convolutional Neural Networks (CNNs) have shown promising results in efficiency and accuracy in image classification. However, their efficacy often relies on large, labeled datasets, posing challenges for applications with limited data…

Machine Learning · Computer Science 2026-01-08 A. M. A. S. D. Alagiyawanna , Asoka Karunananda , A. Mahasinghe , Thushari Silva

Given the complexity of genetic risk prediction, there is a critical need for the development of novel methodologies that can effectively capture intricate genotype--phenotype relationships (e.g., nonlinear) while remaining statistically…

Applications · Statistics 2025-10-03 Heng Ge , Qing Lu

Kernel methods map data into high-dimensional spaces, enabling linear algorithms to learn nonlinear functions without explicitly storing the feature vectors. Quantum kernel methods promise efficient learning by encoding feature maps into…

Quantum Physics · Physics 2025-04-17 Vivek Sabarad , Vishal Varma , T. S. Mahesh

Chimeric antigen receptor T cells (CAR T cells) are dosed similarly to donor lymphocyte infusions following hematopoietic cell transplantation. In this perspective paper a mathematical basis for personalized dosing of CAR T cells is…

Other Quantitative Biology · Quantitative Biology 2019-12-17 Amir A. Toor , Alden Chesney , Jamal Zweit , Jason Reed , Shahrukh Hashmi

Quantitative Structure-Activity Relationship (QSAR) modeling is key in drug discovery, but classical methods face limitations when handling high-dimensional data and capturing complex molecular interactions. This research proposes enhancing…

Quantum Physics · Physics 2025-07-09 Alejandro Giraldo , Daniel Ruiz , Mariano Caruso , Guido Bellomo

Quantum reinforcement learning utilizes quantum layers to process information within a machine learning model. However, both pure and hybrid quantum reinforcement learning face challenges such as data encoding and the use of quantum…

We study the prediction of T-cell response for specific given peptides, which could, among other applications, be a crucial step towards the development of personalized cancer vaccines. It is a challenging task due to limited, heterogeneous…

Cell Behavior · Quantitative Biology 2025-02-28 Josua Stadelmaier , Brandon Malone , Ralf Eggeling

The detection of Alzheimer disease (AD) from clinical MRI data is an active area of research in medical imaging. Recent advances in quantum computing, particularly the integration of parameterized quantum circuits (PQCs) with classical…

Quantum Physics · Physics 2025-03-05 Mominul Islam , Mohammad Junayed Hasan , M. R. C. Mahdy

The application of quantum computation to accelerate machine learning algorithms is one of the most promising areas of research in quantum algorithms. In this paper, we explore the power of quantum learning algorithms in solving an…

Quantum Physics · Physics 2023-04-19 Yusen Wu , Bujiao Wu , Jingbo Wang , Xiao Yuan

Quantum-classical Hybrid Machine Learning (QHML) models are recognized for their robust performance and high generalization ability even for relatively small datasets. These qualities offer unique advantages for anti-cancer drug response…

Machine Learning · Computer Science 2025-05-16 Takafumi Ito , Lysenko Artem , Tatsuhiko Tsunoda

In quantum kernel learning, the primary method involves using a quantum computer to calculate the inner product between feature vectors, thereby obtaining a Gram matrix used as a kernel in machine learning models such as support vector…

Quantum Physics · Physics 2024-05-17 Hiroshi Yamauchi , Tomah Sogabe , Rodney Van Meter

Kernel quantile regression (KQR) extends classical quantile regression to nonlinear settings using kernel methods, offering a powerful tool for modeling conditional distributions. However, its application to large-scale datasets remains…

Optimization and Control · Mathematics 2026-04-24 Shengxiang Deng , Xudong Li , Yangjing Zhang

Since the entry of kernel theory in the field of quantum machine learning, quantum kernel methods (QKMs) have gained increasing attention with regard to both probing promising applications and delivering intriguing research insights.…

Quantum Physics · Physics 2025-04-29 Jan Schnabel , Marco Roth

We compare a parameterized quantum kernel (pQK) with a quantum leaky integrate-and-fire (QLIF) neuromorphic computing approach that employs either the Victor-Purpura or van Rossum kernel in a spectral clustering task, as well as the…

Quantum Physics · Physics 2026-04-14 Donovan Slabbert , Dean Brand , Francesco Petruccione

Quantum machine learning could possibly become a valuable alternative to classical machine learning for applications in High Energy Physics by offering computational speed-ups. In this study, we employ a support vector machine with a…

Classification is at the core of data-driven prediction and decision-making, representing a fundamental task in supervised machine learning. Recently, several quantum machine learning algorithms that use quantum kernels as a measure of…

Quantum Physics · Physics 2024-08-12 Jungyun Lee , Daniel K. Park

Quantum computing represents a paradigm shift for computation requiring an entirely new computer architecture. However, there is much that can be learned from traditional classical computer engineering. In this paper, we describe the…

Quantum Physics · Physics 2022-11-03 A. Y. Matsuura , Timothy G. Mattson

Kernel methods are of current interest in quantum machine learning due to similarities with quantum computing in how they process information in high-dimensional feature (Hilbert) spaces. Kernels are believed to offer particular advantages…

Quantum Physics · Physics 2024-04-03 Carolyn Wood , Sally Shrapnel , G J Milburn

Quantum kernel method is one of the key approaches to quantum machine learning, which has the advantages that it does not require optimization and has theoretical simplicity. By virtue of these properties, several experimental…

Quantum Physics · Physics 2022-11-28 Norihito Shirai , Kenji Kubo , Kosuke Mitarai , Keisuke Fujii

Quantum centric supercomputing (QCSC) framework, such as sample-based quantum diagonalization (SQD) holds immense promise toward achieving practical quantum utility to solve challenging problems. QCSC leverages quantum computers to perform…