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Recent advancements in large language models (LLMs) have resulted in increasingly anthropomorphic language concerning the ability of LLMs to reason. Whether reasoning in LLMs should be understood to be inherently different is, however,…

Machine Learning · Computer Science 2025-07-28 Bertram Højer , Oliver Jarvis , Stefan Heinrich

Large Language Models (LLMs) employ three popular training approaches: Masked Language Models (MLM), Causal Language Models (CLM), and Sequence-to-Sequence Models (seq2seq). However, each approach has its strengths and limitations, and…

Machine Learning · Computer Science 2025-02-18 Xuefeng Liu , Songhao Jiang , Bo Li , Rick Stevens

We introduce LLMD, a large language model designed to analyze a patient's medical history based on their medical records. Along with domain knowledge, LLMD is trained on a large corpus of records collected over time and across facilities,…

Large language models (LLMs) often achieve strong performance on reasoning benchmarks, but final-answer accuracy alone does not show whether they faithfully execute the procedure specified in a prompt. We introduce a controlled diagnostic…

Computation and Language · Computer Science 2026-05-26 Sailesh Panda , Pritam Kadasi , Abhishek Upperwal , Mayank Singh

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Recent advancements in large language models (LLMs) have shown promise in medical applications such as disease diagnosis and treatment planning. However, most existing medical LLMs struggle with the deep reasoning required for complex…

Computation and Language · Computer Science 2025-07-31 Hongzhou Yu , Tianhao Cheng , Yingwen Wang , Wen He , Qing Wang , Ying Cheng , Yuejie Zhang , Rui Feng , Xiaobo Zhang

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

Computation and Language · Computer Science 2025-03-06 Guangfu Guo , Kai Zhang , Bryan Hoo , Yujun Cai , Xiaoqian Lu , Nanyun Peng , Yiwei Wang

Medical consultations are intrinsically speech-centric. However, most prior works focus on long-text-based interactions, which are cumbersome and patient-unfriendly. Recent advances in speech language models (SpeechLMs) have enabled more…

Computation and Language · Computer Science 2026-04-21 Sirry Chen , Jieyi Wang , Wei Chen , Zhongyu Wei

Machine learning for early prediction in medicine has recently shown breakthrough performance, however, the focus on improving prediction accuracy has led to a neglect of faithful explanations that are required to gain the trust of medical…

Computation and Language · Computer Science 2025-12-04 Michael Staniek , Artem Sokolov , Stefan Riezler

Recent advances in reasoning with large language models (LLMs)has shown remarkable reasoning capabilities in domains such as mathematics and coding, yet their application to clinical diagnosis remains underexplored. Here, we introduce…

Computation and Language · Computer Science 2025-04-16 Wuyang Lan , Wenzheng Wang , Changwei Ji , Guoxing Yang , Yongbo Zhang , Xiaohong Liu , Song Wu , Guangyu Wang

The instruction-following ability of large language models enables humans to interact with AI agents in a natural way. However, when required to generate responses of a specific length, large language models often struggle to meet users'…

Computation and Language · Computer Science 2024-10-02 Jiaming Li , Lei Zhang , Yunshui Li , Ziqiang Liu , yuelin bai , Run Luo , Longze Chen , Min Yang

Large Language Models (LLMs) have demonstrated strong reasoning capabilities across various tasks. However, even minor variations in query phrasing, despite preserving the underlying semantic meaning, can significantly affect their…

Computation and Language · Computer Science 2025-02-26 Yihang Yao , Zhepeng Cen , Miao Li , William Han , Yuyou Zhang , Emerson Liu , Zuxin Liu , Chuang Gan , Ding Zhao

Improving the multi-step reasoning ability of Large Language Models (LLMs) is a critical yet challenging task. The dominant paradigm, outcome-supervised reinforcement learning (RLVR), rewards only correct final answers, often propagating…

Artificial Intelligence · Computer Science 2025-10-14 Beining Wang , Weihang Su , Hongtao Tian , Tao Yang , Yujia Zhou , Ting Yao , Qingyao Ai , Yiqun Liu

Reasoning language models have shown an uncanny ability to improve performance at test-time by ``thinking longer''-that is, by generating longer chain-of-thought sequences and hence using more compute. However, the length of their…

Computation and Language · Computer Science 2025-10-06 Pranjal Aggarwal , Sean Welleck

Recently, large language model (LLM) based artificial intelligence (AI) systems have demonstrated remarkable capabilities in natural language understanding and generation. However, these models face a significant challenge when it comes to…

Large Language Models (LLMs) have demonstrated remarkable performance across various natural language tasks, marking significant strides towards general artificial intelligence. While general artificial intelligence is leveraged by…

Computation and Language · Computer Science 2023-10-31 Yizhe Yang , Huashan Sun , Jiawei Li , Runheng Liu , Yinghao Li , Yuhang Liu , Heyan Huang , Yang Gao

Scientific reasoning, the process through which humans apply logic, evidence, and critical thinking to explore and interpret scientific phenomena, is essential in advancing knowledge reasoning across diverse fields. However, despite…

Computation and Language · Computer Science 2026-04-21 Yibo Yan , Shen Wang , Jiahao Huo , Jingheng Ye , Zhendong Chu , Xuming Hu , Philip S. Yu , Carla Gomes , Bart Selman , Qingsong Wen

Recent work has demonstrated the remarkable potential of Large Language Models (LLMs) in test-time scaling. By making models think before answering, they are able to achieve much higher accuracy with extra inference computation. However, in…

Artificial Intelligence · Computer Science 2025-05-22 Yi Sun , Han Wang , Jiaqiang Li , Jiacheng Liu , Xiangyu Li , Hao Wen , Yizhen Yuan , Huiwen Zheng , Yan Liang , Yuanchun Li , Yunxin Liu

Aligning language models (LMs) with user intent is becoming increasingly relevant to enhance user experience. This calls for designing methods that can allow users to control the properties of the language that LMs generate, for example,…

Computation and Language · Computer Science 2025-09-23 Vinay Samuel , Harshita Diddee , Yiming Zhang , Daphne Ippolito
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