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When applying a Deep Learning model to medical images, it is crucial to estimate the model uncertainty. Voxel-wise uncertainty is a useful visual marker for human experts and could be used to improve the model's voxel-wise output, such as…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

Optical flow estimation can be formulated as an end-to-end supervised learning problem, which yields estimates with a superior accuracy-runtime tradeoff compared to alternative methodology. In this paper, we make such networks estimate…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Eddy Ilg , Özgün Çiçek , Silvio Galesso , Aaron Klein , Osama Makansi , Frank Hutter , Thomas Brox

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

As Large Language Models (LLMs) are increasingly integrated in diverse applications, obtaining reliable measures of their predictive uncertainty has become critically important. A precise distinction between aleatoric uncertainty, arising…

While generative models have become increasingly prevalent across various domains, fundamental concerns regarding their reliability persist. A crucial yet understudied aspect of these models is the uncertainty quantification surrounding…

Machine Learning · Computer Science 2025-11-17 Giorgio Morales , Frederic Jurie , Jalal Fadili

Flow Matching (FM) is a recent generative modelling technique: we aim to learn how to sample from distribution $\mathfrak{X}_1$ by flowing samples from some distribution $\mathfrak{X}_0$ that is easy to sample from. The key trick is that…

Differential Geometry · Mathematics 2025-10-24 Finn M. Sherry , Bart M. N. Smets

In this study, we explore in depth a few under-studied topics at the intersection of uncertainty estimation and segmentation. Prior work has shown that the quality of uncertainty estimates can be very sensitive to a range of variables. As…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Michael Smith , Frank P. Ferrie

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

An often overlooked problem in medical image segmentation research is the effective selection of training subsets to annotate from a complete set of unlabelled data. Many studies select their training sets at random, which may lead to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Stephen Lloyd-Brown , Susan Francis , Caroline Hoad , Penny Gowland , Karen Mullinger , Andrew French , Xin Chen

The self-configuring nnU-Net has achieved leading performance in a large range of medical image segmentation challenges. It is widely considered as the model of choice and a strong baseline for medical image segmentation. However, despite…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Yidong Zhao , Changchun Yang , Artur Schweidtmann , Qian Tao

Generative AI has achieved remarkable empirical success, but from the perspective of statistics it often remains opaque: its predictions may be accurate, yet the underlying mechanism is difficult to interpret, analyze, and trust. This book…

Machine Learning · Statistics 2026-03-11 Shinto Eguchi

Knowing when a trained segmentation model is encountering data that is different to its training data is important. Understanding and mitigating the effects of this play an important part in their application from a performance and…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 David S. W. Williams , Daniele De Martini , Matthew Gadd , Paul Newman

Although the existing uncertainty-based semi-supervised medical segmentation methods have achieved excellent performance, they usually only consider a single uncertainty evaluation, which often fails to solve the problem related to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Yuanpeng He , Lijian Li

Rare diseases dominate the diagnostic challenge in medical imaging yet are severely underrepresented in clinical datasets, causing classifiers to fail on exactly the conditions where reliable detection matters most. Generative augmentation…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Felix Nützel , Mischa Dombrowski , Bernhard Kainz

Semi-supervised learning has made significant strides in the medical domain since it alleviates the heavy burden of collecting abundant pixel-wise annotated data for semantic segmentation tasks. Existing semi-supervised approaches enhance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Xu Zheng , Chong Fu , Haoyu Xie , Jialei Chen , Xingwei Wang , Chiu-Wing Sham

Flow matching has become a leading framework for generative modeling, but quantifying the uncertainty of its samples remains an open problem. Existing approaches retrain the model with auxiliary variance heads, maintain costly ensembles, or…

Machine Learning · Computer Science 2026-05-22 Jiarui Xing , Song Wang , Jian Wang

Semantic segmentation of medical images is an essential first step in computer-aided diagnosis systems for many applications. However, given many disparate imaging modalities and inherent variations in the patient data, it is difficult to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Bhavani Sambaturu , Ashutosh Gupta , C. V. Jawahar , Chetan Arora

Segmentation of curvilinear structures such as vasculature and road networks is challenging due to relatively weak signals and complex geometry/topology. To facilitate and accelerate large scale annotation, one has to adopt semi-automatic…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Saumya Gupta , Yikai Zhang , Xiaoling Hu , Prateek Prasanna , Chao Chen

Diffusion and flow-based generative models have shown strong potential for image restoration. However, image denoising under unknown and varying noise conditions remains challenging, because the learned vector fields may become inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Jigang Duan , Genwei Ma , Xu Jiang , Wenfeng Xu , Ping Yang , Xing Zhao

Segmenting visual stimuli into distinct groups of features and visual objects is central to visual function. Classical psychophysical methods have helped uncover many rules of human perceptual segmentation, and recent progress in machine…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Jonathan Vacher , Claire Launay , Pascal Mamassian , Ruben Coen-Cagli
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