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Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

Computation · Statistics 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

The outbreak of an infectious disease in a human population can lead to individuals responding with preventive measures in an attempt to avoid getting infected. This leads to changes in contact patterns. However, as we show in this paper,…

Populations and Evolution · Quantitative Biology 2018-05-15 Ka Yin Leung , Frank Ball , David Sirl , Tom Britton

The S.I.R. model (Susceptible, Infected, Recovered or Died) was proposed by chemistry Willam Kermack (1927) and the mathematician G. Mc. Kendrick (1932). the model supposes to divide to the individuals of a population in three categories.…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Horacio Castellini , Lilia Romanelli

In infectious disease modelling, the expected time from endemicity to extinction (of infection) may be analysed via WKB approximation, a method with origins in mathematical physics. The method is very general, but its uptake to date may…

Dynamical Systems · Mathematics 2024-12-20 Damian Clancy , John J. H. Stewart

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

We introduce a kinetic model that couples the movement of a population of individuals with the dynamics of a pathogen in the same population. We consider that transmission occurs when a susceptible and an infectious individual are…

Analysis of PDEs · Mathematics 2026-01-30 Carolina Strecht-Fernandes , Fabio A. C. C. Chalub

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

Physics and Society · Physics 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta

Classical compartmental models in epidemiology often assume a homogeneous population for simplicity, which neglects the inherent heterogeneity among individuals. This assumption frequently leads to inaccurate predictions when applied to…

Populations and Evolution · Quantitative Biology 2024-09-09 Ning Jiang , Weiqi Chu , Yao Li

Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

Physics and Society · Physics 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

This article introduces epidemia, an R package for Bayesian, regression-oriented modeling of infectious diseases. The implemented models define a likelihood for all observed data while also explicitly modeling transmission dynamics: an…

Virus transmission from person to person is an emergency event facing the global public. Early detection and isolation of potentially susceptible crowds can effectively control the epidemic of its disease. Existing metrics can not correctly…

Databases · Computer Science 2020-04-15 Huajun He , Ruiyuan Li , Rubin Wang , Jie Bao , Yu Zheng , Tianrui Li

The accurate estimation of time-varying transmission rates is fundamental for understanding infectious disease dynamics and implementing effective public health interventions. To this end, we propose an improved inverse method for…

Populations and Evolution · Quantitative Biology 2025-12-17 Shuanglin Jing , Yuting Huang , Hai-Feng Huo

The vast majority of models for the spread of communicable diseases are parametric in nature and involve underlying assumptions about how the disease spreads through a population. In this article we consider the use of Bayesian…

Methodology · Statistics 2017-06-12 Theodore Kypraios , Philip D. O'Neill

Although traditional models of epidemic spreading focus on the number of infected, susceptible and recovered individuals, a lot of attention has been devoted to integrate epidemic models with population genetics. Here we develop an…

Populations and Evolution · Quantitative Biology 2021-11-24 Vitor M. Marquioni , Marcus A. M. de Aguiar

The networked structure of contacts shapes the spreading of epidemic processes. Recent advances on network theory have improved our understanding of the epidemic processes at large scale. The relevance of several considerations still needs…

Physics and Society · Physics 2019-02-21 Sergio Gómez , Alberto Fernández , Sandro Meloni , Alex Arenas

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

We develop a mathematical framework to study the economic impact of infectious diseases by integrating epidemiological dynamics with a kinetic model of wealth exchange. The multi-agent description leads to study the evolution over time of a…

Physics and Society · Physics 2020-08-12 G. Dimarco , L. Pareschi , G. Toscani , M. Zanella

Identifying areas in a landscape where individuals have a higher likelihood of disease infection is key to managing diseases. Unlike conventional methods relying on ecological assumptions, we perform a novel epidemiological tomography for…

Mathematical modelling of the spread of epidemics has been an interesting challenge in the field of epidemiology. The SIR Model proposed by Kermack and McKendrick in 1927 is a prototypical model of epidemiology. However, it has its…

Populations and Evolution · Quantitative Biology 2021-04-13 Agniva Datta , Muktish Acharyya