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Current pain assessment within hospitals often relies on self-reporting or non-specific EKG vital signs. This system leaves critically ill, sedated, and cognitively impaired patients vulnerable to undertreated pain and opioid overuse.…

Machine Learning · Computer Science 2025-10-08 Aavid Mathrawala , Dhruv Kurup , Josie Lau

Multimodal sentiment analysis, a pivotal task in affective computing, seeks to understand human emotions by integrating cues from language, audio, and visual signals. While many recent approaches leverage complex attention mechanisms and…

Computation and Language · Computer Science 2025-05-09 Nischal Mandal , Yang Li

Physiological signals are often corrupted by motion artifacts, baseline drift, and other low-SNR disturbances, which pose significant challenges for analysis. Additionally, these signals exhibit strong non-stationarity, with sharp peaks and…

Machine Learning · Computer Science 2025-10-21 Yanlong Chen , Mattia Orlandi , Pierangelo Maria Rapa , Simone Benatti , Luca Benini , Yawei Li

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

This paper introduces TinyEmo, a family of small multi-modal language models for emotional reasoning and classification. Our approach features: (1) a synthetic emotional instruct dataset for both pre-training and fine-tuning stages, (2) a…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Cristian Gutierrez

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Blood pressure (BP) is a key indicator of cardiovascular health. As hypertension remains a global cause of morbidity and mortality, accurate, continuous, and non-invasive BP monitoring is therefore of paramount importance.…

Signal Processing · Electrical Eng. & Systems 2025-10-20 Bálint Tóth , Dominik Senti , Thorir Mar Ingolfsson , Jeffrey Zweidler , Alexandre Elsig , Luca Benini , Yawei Li

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

Pain is a complex and subjective experience that poses a number of measurement challenges. While self-report by the patient is viewed as the gold standard of pain assessment, this approach fails when patients cannot verbally communicate…

Computers and Society · Computer Science 2017-09-06 Daniel Lopez-Martinez , Rosalind Picard

In the last decade, researchers have increasingly explored using biosensing technologies for music-based affective regulation and stress management interventions in laboratory and real-world settings. These systems -- including interactive…

Human-Computer Interaction · Computer Science 2025-07-23 Natasha Yamane , Varun Mishra , Matthew S. Goodwin

Assessing pain in patients unable to speak (also called non-verbal patients) is extremely complicated and often is done by clinical judgement. However, this method is not reliable since patients vital signs can fluctuate significantly due…

Machine Learning · Computer Science 2020-12-29 Raul Fernandez Rojas , Julio Romero , Jehu Lopez-Aparicio , Keng-Liang Ou

Physiological foundation models (FMs) have shown promise for biosignal representation learning, yet most remain confined to a single modality such as EEG, ECG, or PPG, largely because paired multimodal datasets are scarce. In this paper, we…

Artificial Intelligence · Computer Science 2026-04-07 Marija Zelic , Anna Tegon , Yawei Li , Thorir Mar Ingolfsson , Luca Benini

Pathological diagnosis remains the definitive standard for identifying tumors. The rise of multimodal large models has simplified the process of integrating image analysis with textual descriptions. Despite this advancement, the substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Xiaomin Wu , Rui Xu , Pengchen Wei , Wenkang Qin , Peixiang Huang , Ziheng Li , Lin Luo

Multimodal physiological signals, such as EEG, ECG, EOG, and EMG, are crucial for healthcare and brain-computer interfaces. While existing methods rely on specialized architectures and dataset-specific fusion strategies, they struggle to…

Signal Processing · Electrical Eng. & Systems 2026-03-18 Wei-Bang Jiang , Xi Fu , Yi Ding , Cuntai Guan

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Electroencephalography (EEG) serves as an essential diagnostic tool in neurology; however, its accurate manual interpretation is a time-intensive process that demands highly specialized expertise, which remains relatively scarce and not…

Quantitative Methods · Quantitative Biology 2025-03-14 Ruggero G. Bettinardi , Mohamed Rahmouni , Ulysse Gimenez

Cardiovascular disease remains the leading cause of global mortality, yet scalable cardiac monitoring is hindered by the gap between diagnostic-rich ECG and ubiquitous wearable PPG. Bridging this gap requires representations that are…

Machine Learning · Computer Science 2026-05-12 Zhangdaihong Liu , Chang Liu , Fenglin Liu , Yixuan Chen , Yang Yang , David A. Clifton , Xiao Gu

Biomedical imaging is unequivocally dependent on the ability to reconstruct interpretable and high-quality images from acquired sensor data. This reconstruction process is pivotal across many applications, spanning from magnetic resonance…

Signal Processing · Electrical Eng. & Systems 2019-09-24 Ben Luijten , Regev Cohen , Frederik J. de Bruijn , Harold A. W. Schmeitz , Massimo Mischi , Yonina C. Eldar , Ruud J. G. van Sloun

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

Motor imagery brain--machine interfaces enable us to control machines by merely thinking of performing a motor action. Practical use cases require a wearable solution where the classification of the brain signals is done locally near the…

Signal Processing · Electrical Eng. & Systems 2021-12-21 Xiaying Wang , Lukas Cavigelli , Tibor Schneider , Luca Benini