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Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Xingda Li

Diffuse correlation spectroscopy (DCS) is a noninvasive optical technique that probes microvascular blood flow in deep tissues. Here, we present and validate a new on-chip hardware correlator for high-speed DCS measurements. The correlator…

Diffuse Correlation Spectroscopy (DCS) allows the label-free investigation of microvascular dynamics deep within living tissue. However, common implementations of DCS are currently limited to measurement depths of $\sim 1-1.5cm$, which can…

It has been shown that light speckle fluctuations provide a means for noninvasive measurements of cerebral blood flow index (CBFi). While conventional Diffuse Correlation Spectroscopy (DCS) provides marginal brain sensitivity for CBFi in…

Significance: Cerebral blood flow (CBF) imaging is crucial for diagnosing cerebrovascular diseases. However, existing large neuroimaging techniques with high cost, low sampling rate, and poor mobility make them unsuitable for continuous and…

Tissues and Organs · Quantitative Biology 2024-08-26 Faezeh Akbari , Xuhui Liu , Fatemeh Hamedi , Mehrana Mohtasebi , Lei Chen , Guoqiang Yu

Significance: Measuring cerebral blood flow (CBF) is crucial for diagnosing various cerebral diseases. An affordable, wearable, and fiber-free continuous-wave speckle contrast flowmetry (CW-DSCF) technique has been developed for continuous…

Quantitative Methods · Quantitative Biology 2025-02-13 Chaebeom Yeo , Xuhui Liu , Mehrana Mohtasebi , Faezeh Akbari , Faraneh Fathi , Guoqiang Yu

We introduce a rapid and precise analytical approach for analyzing cerebral blood flow (CBF) using Diffuse Correlation Spectroscopy (DCS) with the application of the Extreme Learning Machine (ELM). Our evaluation of ELM and existing…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Zhenya Zang , Xingda Li

Diffuse correlation spectroscopy (DCS) is a powerful tool for assessing microvascular hemodynamic in deep tissues. Recent advances in sensors, lasers, and deep learning have further boosted the development of new DCS methods. However,…

Speckle contrast optical spectroscopy (SCOS) offers a non-invasive and cost-effective method for monitoring cerebral blood flow (CBF). However, extracting accurate CBF from SCOS necessitates precise noise pre-calibration. Errors from this…

Signal Processing · Electrical Eng. & Systems 2025-06-23 Ninghe Liu , Yu Xi Huang , Simon Mahler , Changhuei Yang

Discriminative correlation filters (DCF) with deep convolutional features have achieved favorable performance in recent tracking benchmarks. However, most of existing DCF trackers only consider appearance features of current frame, and…

Computer Vision and Pattern Recognition · Computer Science 2018-02-28 Zheng Zhu , Wei Wu , Wei Zou , Junjie Yan

We propose a dual pathway, 11-layers deep, three-dimensional Convolutional Neural Network for the challenging task of brain lesion segmentation. The devised architecture is the result of an in-depth analysis of the limitations of current…

Computer Vision and Pattern Recognition · Computer Science 2017-01-10 Konstantinos Kamnitsas , Christian Ledig , Virginia F. J. Newcombe , Joanna P. Simpson , Andrew D. Kane , David K. Menon , Daniel Rueckert , Ben Glocker

In the realm of cerebrovascular monitoring, primary metrics typically include blood pressure, which influences cerebral blood flow (CBF) and is contingent upon vessel radius. Measuring CBF non-invasively poses a persistent challenge,…

To address many of the deficiencies in optical neuroimaging technologies such as poor spatial resolution, time-consuming reconstruction, low penetration depth, and contact-based measurement, a novel, noncontact, time-resolved laser speckle…

Supersonic engine development requires accurate and detailed measurements of fluidic and thermodynamic parameters to optimize engine designs and benchmark computational fluid dynamic (CFD) simulations. Here, we demonstrate that dual…

Widely used traditional pipelines for subcortical brain segmentation are often inefficient and slow, particularly when processing large datasets. Furthermore, deep learning models face challenges due to the high resolution of MRI images and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Aaron Cao , Zongyu Li , Jordan Jomsky , Andrew F. Laine , Jia Guo

In vivo cardiac diffusion tensor imaging (cDTI) is a promising Magnetic Resonance Imaging (MRI) technique for evaluating the micro-structure of myocardial tissue in the living heart, providing insights into cardiac function and enabling the…

Hybrid methods for simulating rarefied gas flows reduce computational cost by coupling a particle-based model, typically the direct simulation Monte Carlo (DSMC) method, to a continuum-based solver, i.e. a computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2026-04-28 Arshad Kamal , Arun K. Chinnappan , James R. Kermode , Duncan A. Lockerby

Fast and accurate waveform simulation is critical for understanding fiber channel characteristics, developing digital signal processing (DSP) technologies, optimizing optical network configurations, and advancing the optical fiber…

Signal Processing · Electrical Eng. & Systems 2025-11-04 Minghui Shi , Hang Yang , Zekun Niu , Chuyan Zeng , Junzhe Xiao , Yunfan Zhang , Mingzhe Chen , Weisheng Hu , Lilin Yi

Federated Retrieval (FR) routes queries across multiple external knowledge sources, to mitigate hallucinations of LLMs, when necessary external knowledge is distributed. However, existing methods struggle to retrieve high-quality and…

Machine Learning · Computer Science 2025-10-15 Zhibang Yang , Xinke Jiang , Rihong Qiu , Ruiqing Li , Yihang Zhang , Yue Fang , Yongxin Xu , Hongxin Ding , Xu Chu , Junfeng Zhao , Yasha Wang
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