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Imaging technologies are fundamental to biomedical research and modern medicine, requiring analysis of high-resolution images across various modalities. While multimodal large language models (MLLMs) show promise for biomedical image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Liangyu Chen , James Burgess , Jeffrey J Nirschl , Orr Zohar , Serena Yeung-Levy

Contemporary medical contrastive learning faces challenges from inconsistent semantics and sample pair morphology, leading to dispersed and converging semantic shifts. The variability in text reports, due to multiple authors, complicates…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Shreyank N Gowda , David A. Clifton

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Tao Tang , Shijie Xu , Jionglong Su , Zhixiang Lu

Vision-and-Language Pre-training (VLP) improves model performance for downstream tasks that require image and text inputs. Current VLP approaches differ on (i) model architecture (especially image embedders), (ii) loss functions, and (iii)…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Tarik Arici , Mehmet Saygin Seyfioglu , Tal Neiman , Yi Xu , Son Train , Trishul Chilimbi , Belinda Zeng , Ismail Tutar

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Despite tremendous progress in computer vision, there has not been an attempt for machine learning on very large-scale medical image databases. We present an interleaved text/image deep learning system to extract and mine the semantic…

Computer Vision and Pattern Recognition · Computer Science 2015-05-05 Hoo-Chang Shin , Le Lu , Lauren Kim , Ari Seff , Jianhua Yao , Ronald M. Summers

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Automatic medical image report generation has drawn growing attention due to its potential to alleviate radiologists' workload. Existing work on report generation often trains encoder-decoder networks to generate complete reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Jianmo Ni , Chun-Nan Hsu , Amilcare Gentili , Julian McAuley

Accurate disease interpretation from radiology remains challenging due to imaging heterogeneity. Achieving expert-level diagnostic decisions requires integration of subtle image features with clinical knowledge. Yet major vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Difei Gu , Yunhe Gao , Mu Zhou , Dimitris Metaxas

Vision-Language Models (VLMs) are becoming increasingly popular in the medical domain, bridging the gap between medical images and clinical language. Existing VLMs demonstrate an impressive ability to comprehend medical images and text…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Bidur Khanal , Sandesh Pokhrel , Sanjay Bhandari , Ramesh Rana , Nikesh Shrestha , Ram Bahadur Gurung , Cristian Linte , Angus Watson , Yash Raj Shrestha , Binod Bhattarai

We introduce a new pretraining approach geared for multi-document language modeling, incorporating two key ideas into the masked language modeling self-supervised objective. First, instead of considering documents in isolation, we pretrain…

Computation and Language · Computer Science 2021-09-06 Avi Caciularu , Arman Cohan , Iz Beltagy , Matthew E. Peters , Arie Cattan , Ido Dagan

Medical report generation from imaging data remains a challenging task in clinical practice. While large language models (LLMs) show great promise in addressing this challenge, their effective integration with medical imaging data still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Chunlei Li , Jingyang Hou , Yilei Shi , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Large Language Models (LLMs) have demonstrated remarkable performance across various domains, including healthcare. However, their ability to effectively represent structured non-textual data, such as the alphanumeric medical codes used in…

Vision-language pre-training has recently gained popularity as it allows learning rich feature representations using large-scale data sources. This paradigm has quickly made its way into the medical image analysis community. In particular,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Julio Silva-Rodríguez , Jose Dolz , Ismail Ben Ayed

Medical vision-language models (VLMs) show strong performance on radiology tasks but often produce fluent yet weakly grounded conclusions due to over-reliance on a dominant modality. We introduce a context-aligned reasoning framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Sumra Khan , Sagar Chhabriya , Aizan Zafar , Sheeraz Arif , Amgad Muneer , Anas Zafar , Shaina Raza , Rizwan Qureshi

With the significant advancements of Large Language Models (LLMs) in the field of Natural Language Processing (NLP), the development of image-text multimodal models has garnered widespread attention. Current surveys on image-text multimodal…

Computation and Language · Computer Science 2024-06-21 Ruifeng Guo , Jingxuan Wei , Linzhuang Sun , Bihui Yu , Guiyong Chang , Dawei Liu , Sibo Zhang , Zhengbing Yao , Mingjun Xu , Liping Bu

Automated radiology report drafting (ARRD) using vision-language models (VLMs) has advanced rapidly, yet most systems lack explicit uncertainty estimates, limiting trust and safe clinical deployment. We propose CONRep, a model-agnostic…

Large language models (LLMs) have demonstrated that large-scale pretraining enables systems to adapt rapidly to new problems with little supervision in the language domain. This success, however, has not translated as effectively to the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Pablo Acuaviva , Aram Davtyan , Mariam Hassan , Sebastian Stapf , Ahmad Rahimi , Alexandre Alahi , Paolo Favaro

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

We introduce a radiology-focused visual language model designed to generate radiology reports from chest X-rays. Building on previous findings that large language models (LLMs) can acquire multimodal capabilities when aligned with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Xi Zhang , Zaiqiao Meng , Jake Lever , Edmond S. L. Ho
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