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Clinical machine learning models experience significantly degraded performance in datasets not seen during training, e.g., new hospitals or populations. Recent developments in domain generalization offer a promising solution to this problem…

Machine Learning · Computer Science 2021-04-16 Haoran Zhang , Natalie Dullerud , Laleh Seyyed-Kalantari , Quaid Morris , Shalmali Joshi , Marzyeh Ghassemi

In recent years, machine learning has made significant progress in clinical outcome prediction, demonstrating increasingly accurate results. However, the substantial resources required for hospitals to train these models, such as data…

Machine Learning · Computer Science 2026-05-06 Ryan King , Conrad Krueger , Ethan Veselka , Tianbao Yang , Bobak J. Mortazavi

Early recognition of risky trajectories during an Intensive Care Unit (ICU) stay is one of the key steps towards improving patient survival. Learning trajectories from physiological signals continuously measured during an ICU stay requires…

Machine Learning · Computer Science 2019-12-24 Tiago Alves , Alberto Laender , Adriano Veloso , Nivio Ziviani

Developing predictive models that perform reliably across diverse patient populations and heterogeneous environments is a core aim of medical research. However, generalization is only possible if the learned model is robust to statistical…

Data augmentation is one of the most effective techniques for regularizing deep learning models and improving their recognition performance in a variety of tasks and domains. However, this holds for standard in-domain settings, in which the…

Multi-domain recommendation leverages domain-general knowledge to improve recommendations across several domains. However, as platforms expand to dozens or hundreds of scenarios, training all domains in a unified model leads to performance…

Information Retrieval · Computer Science 2025-07-10 Huishi Luo , Yiqing Wu , Yiwen Chen , Fuzhen Zhuang , Deqing Wang

Domain generalization has become a critical challenge in predictive healthcare, where different patient groups often exhibit shifting data distributions that degrade model performance. Still, regular domain generalization approaches often…

Machine Learning · Computer Science 2026-02-16 Pengfei Hu , Xiaoxue Han , Fei Wang , Yue Ning

Prediction models often fail if train and test data do not stem from the same distribution. Out-of-distribution (OOD) generalization to unseen, perturbed test data is a desirable but difficult-to-achieve property for prediction models and…

Methodology · Statistics 2022-05-25 Lucas Kook , Beate Sick , Peter Bühlmann

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

We propose a regularisation strategy of classical machine learning algorithms rooted in causality that ensures robustness against distribution shifts. Building upon the anchor regression framework, we demonstrate how incorporating a…

Machine Learning · Statistics 2025-03-12 Homer Durand , Gherardo Varando , Nathan Mankovich , Gustau Camps-Valls

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Unsupervised domain adaption has proven to be an effective approach for alleviating the intensive workload of manual annotation by aligning the synthetic source-domain data and the real-world target-domain samples. Unfortunately, mapping…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Munan Ning , Donghuan Lu , Dong Wei , Cheng Bian , Chenglang Yuan , Shuang Yu , Kai Ma , Yefeng Zheng

Due to the scarcity of publicly available diarization data, the model performance can be improved by training a single model with data from different domains. In this work, we propose to incorporate domain information to train a single…

Sound · Computer Science 2023-12-13 Ivan Fung , Lahiru Samarakoon , Samuel J. Broughton

Domain generalization is a technique aimed at enabling models to maintain high accuracy when applied to new environments or datasets (unseen domains) that differ from the datasets used in training. Generally, the accuracy of models trained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Reiji Saito , Kazuhiro Hotta

With the successful adoption of machine learning on electronic health records (EHRs), numerous computational models have been deployed to address a variety of clinical problems. However, due to the heterogeneity of EHRs, models trained on…

Machine Learning · Computer Science 2021-01-14 Yiqin Yu , Pin-Yu Chen , Yuan Zhou , Jing Mei

Domain adaption has been widely adapted for cross-domain sentiment analysis to transfer knowledge from the source domain to the target domain. Whereas, most methods are proposed under the assumption that the target (test) domain is known,…

Computation and Language · Computer Science 2024-02-23 Siyin Wang , Jie Zhou , Qin Chen , Qi Zhang , Tao Gui , Xuanjing Huang

The well known domain shift issue causes model performance to degrade when deployed to a new target domain with different statistics to training. Domain adaptation techniques alleviate this, but need some instances from the target domain to…

Machine Learning · Computer Science 2019-06-11 Yiying Li , Yongxin Yang , Wei Zhou , Timothy M. Hospedales

Despite being very powerful in standard learning settings, deep learning models can be extremely brittle when deployed in scenarios different from those on which they were trained. Domain generalization methods investigate this problem and…

Computer Vision and Pattern Recognition · Computer Science 2021-01-28 Francesco Cappio Borlino , Antonio D'Innocente , Tatiana Tommasi

Unsupervised domain adaption has been widely adopted in tasks with scarce annotated data. Unfortunately, mapping the target-domain distribution to the source-domain unconditionally may distort the essential structural information of the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Munan Ning , Donghuan Lu , Yujia Xie , Dongdong Chen , Dong Wei , Yefeng Zheng , Yonghong Tian , Shuicheng Yan , Li Yuan
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