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We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…

This paper extends the mathematical theory of axisymmetrization and vorticity depletion within the two-dimensional (2D) Euler equations, with an emphasis on the dynamics of radially symmetric, monotonic vorticity profiles. By analyzing…

Fluid Dynamics · Physics 2024-11-14 Rômulo Damasclin Chaves dos Santos

Left ventricular (LV) stiffness and contractility, characterized by the end-diastolic and end-systolic pressure-volume relationships (EDPVR & ESPVR), are two important indicators of the performance of the human heart. Although much research…

Medical Physics · Physics 2023-08-22 Yunxiao Zhang , Moritz Kalhöfer-Köchling , Eberhard Bodenschatz , Yong Wang

Understanding the movement of the left ventricle myocardium (LVmyo) during the cardiac cycle is essential for assessing cardiac function. One way to model this movement is through a series of deformable image registrations (DIRs) of the…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Mathias Micheelsen Lowes , Jonas Jalili Pedersen , Bjørn S. Hansen , Klaus Fuglsang Kofoed , Maxime Sermesant , Rasmus R. Paulsen

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

We present an hybrid VOF/embedded boundary method allowing to model two-phase flows in presence of solids with arbitrary shapes. The method relies on the coupling of existing methods: a geometric Volume of fluid (VOF) method to tackle the…

The fluid flow around a bluff body is complex and time dependent, which also contains a wide range of time and length scales. The first few eigenmodes of the proper orthogonal decomposition (POD) of such a flow provide significant insight…

Fluid Dynamics · Physics 2021-11-10 Jahrul Alam , Asokan Variyath

In this paper, we propose a method for tracking structures (e.g., ventricles and myocardium) in cardiac images (e.g., magnetic resonance) by propagating forward in time a previous estimate of the structures via a new deformation estimation…

Computer Vision and Pattern Recognition · Computer Science 2014-02-10 Omar Arif , Ganesh Sundaramoorthi , Byung-Woo Hong , Anthony Yezzi

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

Fluid Dynamics · Physics 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

Cardiac arrhythmias such as ventricular tachycardia (VT) or ventricular fibrillation (VF) are the leading cause of death in the industrialised world. There is a growing consensus that these arrhythmias arise because of the formation of…

Pattern Formation and Solitons · Physics 2007-05-23 T. K. Shajahan , Sitabhra Sinha , Rahul Pandit

Dynamic Mode Decomposition (DMD) is a data-driven and model-free decomposition technique. It is suitable for revealing spatio-temporal features of both numerically and experimentally acquired data. Conceptually, DMD performs a…

Fluid Dynamics · Physics 2020-12-18 Tim Krake , Stefan Reinhardt , Marcel Hlawatsch , Bernhard Eberhardt , Daniel Weiskopf

In this fluid dynamics video, results from high fidelity numerical simulations are presented, which have been carried out to study the flow and droplet dynamics of liquid sheets formed by two impinging jets. A three-dimensional…

Fluid Dynamics · Physics 2011-10-18 Xiaodong Chen , Prashant Khare , Dongjun Ma , Vigor Yang

To predict liquid-gas two-phase flow phenomena, accurate tracking and prediction of the evolving liquid-gas interface is required. Volume-of-Fluid or VoF method has been used in the literature for computationally modeling of such flows. In…

Fluid Dynamics · Physics 2023-01-05 Sucharitha Rajendran , Raj M Manglik , Milind A Jog

The present study is a prelude to applying different flow control devices on pitching and plunging airfoils with the intention of controlling the growth of the leading edge vortex (LEV); hence, the lift under unsteady stall conditions. As a…

An adjoint-based variational optimal mixed model (VOMM) is proposed for subgrid-scale (SGS) closure in large-eddy simulation (LES) of turbulence. The stabilized adjoint LES equations are formulated by introducing a minimal regularization to…

Fluid Dynamics · Physics 2023-07-19 Zelong Yuan , Yunpeng Wang , Xiaoning Wang , Jianchun Wang

Data-driven decompositions are becoming essential tools in fluid dynamics, allowing for tracking the evolution of coherent patterns in large datasets, and for constructing low order models of complex phenomena. In this work, we analyze the…

Fluid Dynamics · Physics 2020-04-15 M. A. Mendez , M. Balabane , J. -M. Buchlin

We review the dynamical behavior of giant fluid vesicles in various types of external hydrodynamic flow. The interplay between stresses arising from membrane elasticity, hydrodynamic flows, and the ever present thermal fluctuations leads to…

Soft Condensed Matter · Physics 2014-05-12 David Abreu , Michael Levant , Victor Steinberg , Udo Seifert

This study creates a physiologically realistic virtual patient database (VPD), representing the human arterial system, for the primary purpose of studying the affects of arterial disease on haemodynamics. A low dimensional representation of…

Medical Physics · Physics 2021-08-05 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

The transient dynamics of a wake vortex, modelled as a strong swirling $q$-vortex, are investigated with a focus on optimal transient growth driven by continuous eigenmodes associated with continuous spectra. The pivotal contribution of…

Fluid Dynamics · Physics 2025-07-02 Sangjoon Lee , Philip S. Marcus

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

Fluid Dynamics · Physics 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan
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