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Regulatory compliance in the pharmaceutical industry entails navigating through complex and voluminous guidelines, often requiring significant human resources. To address these challenges, our study introduces a chatbot model that utilizes…

Computation and Language · Computer Science 2024-02-07 Jaewoong Kim , Moohong Min

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

Computation and Language · Computer Science 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

Biomedical question-answering (QA) systems require effective retrieval and generation components to ensure accuracy, efficiency, and scalability. This study systematically examines a Retrieval-Augmented Generation (RAG) system for…

Information Retrieval · Computer Science 2026-01-14 Linus Stuhlmann , Michael Alexander Saxer , Jonathan Fürst

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Retrieval-Augmented Generation (RAG) has been proposed to mitigate hallucinations in large language models (LLMs), where generated outputs may be factually incorrect. However, existing RAG approaches predominantly rely on vector similarity…

Information Retrieval · Computer Science 2026-04-28 Miao Xie , Xiao Zhang , Yi Li , Chunli Lv

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Accessing accurate medication insights is vital for enhancing patient safety, minimizing errors, and supporting clinical decision-making. However, healthcare professionals in Africa often rely on manual and time-consuming processes to…

Information Retrieval · Computer Science 2025-02-26 Axum AI , : , J. Owoyemi , S. Abubakar , A. Owoyemi , T. O. Togunwa , F. C. Madubuko , S. Oyatoye , Z. Oyetolu , K. Akyea , A. O. Mohammed , A. Adebakin

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Large language models achieve high task performance yet often hallucinate or rely on outdated knowledge. Retrieval-augmented generation (RAG) addresses these gaps by coupling generation with external search. We analyse how hyperparameters…

Machine Learning · Computer Science 2025-05-14 Adel Ammar , Anis Koubaa , Omer Nacar , Wadii Boulila

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

While large language models (LLMs) have achieved state-of-the-art performance on a wide range of medical question answering (QA) tasks, they still face challenges with hallucinations and outdated knowledge. Retrieval-augmented generation…

Computation and Language · Computer Science 2024-02-26 Guangzhi Xiong , Qiao Jin , Zhiyong Lu , Aidong Zhang

Retrieval-augmented generation (RAG) improves large language models (LLMs) by using external knowledge to guide response generation, reducing hallucinations. However, RAG, particularly multi-modal RAG, can introduce new hallucination…

Machine Learning · Computer Science 2025-01-08 Matin Mortaheb , Mohammad A. Amir Khojastepour , Srimat T. Chakradhar , Sennur Ulukus

Retrieval-Augmented Generation (RAG) systems face challenges with complex, multihop questions, and agentic frameworks such as Search-R1 (Jin et al., 2025), which operates iteratively, have been proposed to address these complexities.…

Retrieval-Augmented Generation (RAG) significantly improves the factuality of Large Language Models (LLMs), yet standard pipelines often lack mechanisms to verify inter- mediate reasoning, leaving them vulnerable to hallucinations in…

Computation and Language · Computer Science 2026-03-12 Eeham Khan , Luis Rodriguez , Marc Queudot

Retrieval-augmented generation (RAG) has emerged as a powerful framework for enhancing large language models (LLMs) with external knowledge, particularly in scientific domains that demand specialized and dynamic information. Despite its…

Computation and Language · Computer Science 2026-02-17 Xianrui Zhong , Bowen Jin , Siru Ouyang , Yanzhen Shen , Qiao Jin , Yin Fang , Zhiyong Lu , Jiawei Han

The increasing use of social media to share lived and living experiences of substance use presents a unique opportunity to obtain information on side effects, use patterns, and opinions on novel psychoactive substances. However, due to the…

Developing accurate biomedical Question Answering (QA) systems in low-resource languages remains a major challenge, limiting equitable access to reliable medical knowledge. This paper introduces BanglaMedQA and BanglaMMedBench, the first…

Computation and Language · Computer Science 2025-11-07 Sadia Sultana , Saiyma Sittul Muna , Mosammat Zannatul Samarukh , Ajwad Abrar , Tareque Mohmud Chowdhury

Incorporating specific knowledge into large language models via retrieval-augmented generation (RAG) is a widespread technique that fuels many of today's industry AI applications. A fundamental problem is to assess if the context retrieved…

Information Retrieval · Computer Science 2026-05-08 Florian Geissler , Francesco Carella , Laura Fieback , Jakob Spiegelberg

As AI chatbots gain adoption in clinical medicine, developing effective frameworks for complex, emerging diseases presents significant challenges. We developed and evaluated six Retrieval-Augmented Generation (RAG) corpus configurations for…

Artificial Intelligence · Computer Science 2025-10-20 Philip DiGiacomo , Haoyang Wang , Jinrui Fang , Yan Leng , W Michael Brode , Ying Ding
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