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Human explanations of natural language, rationales, form a tool to assess whether models learn a label for the right reasons or rely on dataset-specific shortcuts. Sufficiency is a common metric for estimating the informativeness of…

Computation and Language · Computer Science 2025-11-21 Jonathan Kamp , Lisa Beinborn , Antske Fokkens

Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…

Artificial Intelligence · Computer Science 2026-01-21 Dipayan Sengupta , Saumya Panda

Work on "learning with rationales" shows that humans providing explanations to a machine learning system can improve the system's predictive accuracy. However, this work has not been connected to work in "explainable AI" which concerns…

Computation and Language · Computer Science 2019-06-03 Julia Strout , Ye Zhang , Raymond J. Mooney

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

Recent developments in machine learning have introduced models that approach human performance at the cost of increased architectural complexity. Efforts to make the rationales behind the models' predictions transparent have inspired an…

Computation and Language · Computer Science 2020-09-29 Pepa Atanasova , Jakob Grue Simonsen , Christina Lioma , Isabelle Augenstein

One of the motivations for explainable AI is to allow humans to make better and more informed decisions regarding the use and deployment of AI models. But careful evaluations are needed to assess whether this expectation has been fulfilled.…

Artificial Intelligence · Computer Science 2023-12-12 Shawn Im , Jacob Andreas , Yilun Zhou

Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…

Artificial Intelligence · Computer Science 2026-05-25 Belona Sonna , Alban Grastien

Among the remarkable emergent capabilities of large language models (LMs) is free-text rationalization; beyond a certain scale, large LMs are capable of generating seemingly useful rationalizations, which in turn, can dramatically enhance…

Computation and Language · Computer Science 2023-05-15 Brihi Joshi , Ziyi Liu , Sahana Ramnath , Aaron Chan , Zhewei Tong , Shaoliang Nie , Qifan Wang , Yejin Choi , Xiang Ren

Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…

Human-Computer Interaction · Computer Science 2024-12-17 Olya Rezaeian , Onur Asan , Alparslan Emrah Bayrak

In the rapidly evolving field of Explainable Natural Language Processing (NLP), textual explanations, i.e., human-like rationales, are pivotal for explaining model predictions and enriching datasets with interpretable labels. Traditional…

Computation and Language · Computer Science 2025-11-12 Mahdi Dhaini , Juraj Vladika , Ege Erdogan , Zineb Attaoui , Gjergji Kasneci

Explanations are hypothesized to improve human understanding of machine learning models and achieve a variety of desirable outcomes, ranging from model debugging to enhancing human decision making. However, empirical studies have found…

Artificial Intelligence · Computer Science 2023-05-02 Chacha Chen , Shi Feng , Amit Sharma , Chenhao Tan

Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these…

Human-Computer Interaction · Computer Science 2025-01-29 Olya Rezaeian , Alparslan Emrah Bayrak , Onur Asan

This paper contributes with a pragmatic evaluation framework for explainable Machine Learning (ML) models for clinical decision support. The study revealed a more nuanced role for ML explanation models, when these are pragmatically embedded…

Artificial Intelligence · Computer Science 2022-12-22 Oskar Wysocki , Jessica Katharine Davies , Markel Vigo , Anne Caroline Armstrong , Dónal Landers , Rebecca Lee , André Freitas

This research on data extraction methods applies recent advances in natural language processing to evidence synthesis based on medical texts. Texts of interest include abstracts of clinical trials in English and in multilingual contexts.…

Computation and Language · Computer Science 2020-01-31 Lena Schmidt , Julie Weeds , Julian P. T. Higgins

Machine learning models that offer excellent predictive performance often lack the interpretability necessary to support integrated human machine decision-making. In clinical medicine and other high-risk settings, domain experts may be…

Machine Learning · Computer Science 2021-04-19 Zach Wood-Doughty , Isabel Cachola , Mark Dredze

Machine learning (ML) systems across many application areas are increasingly demonstrating performance that is beyond that of humans. In response to the proliferation of such models, the field of Explainable AI (XAI) has sought to develop…

Human-Computer Interaction · Computer Science 2020-02-12 Devleena Das , Sonia Chernova

Learning from rationales seeks to augment model prediction accuracy using human-annotated rationales (i.e. subsets of input tokens) that justify their chosen labels, often in the form of intermediate or multitask supervision. While…

Machine Learning · Computer Science 2022-03-30 Samuel Carton , Surya Kanoria , Chenhao Tan

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

AI has the potential to augment human decision making. However, even high-performing models can produce inaccurate predictions when deployed. These inaccuracies, combined with automation bias, where humans overrely on AI predictions, can…

Human-Computer Interaction · Computer Science 2025-08-12 Sarah Jabbour , David Fouhey , Nikola Banovic , Stephanie D. Shepard , Ella Kazerooni , Michael W. Sjoding , Jenna Wiens

The development of neural networks for clinical artificial intelligence (AI) is reliant on interpretability, transparency, and performance. The need to delve into the black-box neural network and derive interpretable explanations of model…

Computation and Language · Computer Science 2021-11-16 Niall Taylor , Lei Sha , Dan W Joyce , Thomas Lukasiewicz , Alejo Nevado-Holgado , Andrey Kormilitzin
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