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The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

The transition to open, distributed Multi-Agent Systems (MAS) promises scalable intelligence but introduces a non-trivial tension: maximizing global efficiency requires cooperative, resource-aware scheduling, yet autonomous agents may be…

Networking and Internet Architecture · Computer Science 2026-03-19 Hongze Liu , Chang Guo , Yingzeng Li , Mengru Wang , Jiong Lou , Shijing Yuan , Hefeng Zhou , Chentao Wu , Jie LI

Powered by the emerging large language models (LLMs), autonomous geographic information systems (GIS) agents have the potential to accomplish spatial analyses and cartographic tasks. However, a research gap exists to support fully…

Information Retrieval · Computer Science 2024-08-09 Huan Ning , Zhenlong Li , Temitope Akinboyewa , M. Naser Lessani

Multi-agent systems built on language models have shown strong performance on collaborative reasoning tasks. However, existing evaluations focus only on the correctness of the final output, overlooking how inefficient communication and poor…

Computation and Language · Computer Science 2025-07-18 Jisoo Lee , Raeyoung Chang , Dongwook Kwon , Harmanpreet Singh , Nikhil Verma

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

Large language model(LLM)-driven multi-agent systems(MAS) coordinate specialized agents through predefined interaction topologies and have shown promise for complex tasks such as competition-level code generation. Recent studies demonstrate…

Multiagent Systems · Computer Science 2026-02-20 Siyu Wang , Ruotian Lu , Zhihao Yang , Yuchao Wang , Yanzhou Zhang , Lei Xu , Qimin Xu , Guojun Yin , Cailian Chen , Xinping Guan

Automatic medical report generation has the potential to support clinical diagnosis, reduce the workload of radiologists, and demonstrate potential for enhancing diagnostic consistency. However, current evaluation metrics often fail to…

Computation and Language · Computer Science 2025-08-06 Zhenxuan Zhang , Kinhei Lee , Peiyuan Jing , Weihang Deng , Huichi Zhou , Zihao Jin , Jiahao Huang , Zhifan Gao , Dominic C Marshall , Yingying Fang , Guang Yang

Large Language Models (LLMs) have shown remarkable capabilities in code generation tasks, yet they face significant limitations in handling complex, long-context programming challenges and demonstrating complex compositional reasoning…

Artificial Intelligence · Computer Science 2025-01-14 Amr Almorsi , Mohanned Ahmed , Walid Gomaa

Although large language models (LLMs) have revolutionized natural language processing capabilities, their practical implementation as autonomous multi-agent systems (MAS) for industrial problem-solving encounters persistent barriers.…

Computation and Language · Computer Science 2025-10-30 Hui Yi Leong , Yuheng Li , Yuqing Wu , Wenwen Ouyang , Wei Zhu , Jiechao Gao , Wei Han

Drug discovery remains a formidable challenge: more than 90 percent of candidate molecules fail in clinical evaluation, and development costs often exceed one billion dollars per approved therapy. Disparate data streams, from genomics and…

Artificial Intelligence · Computer Science 2025-04-28 Kevin Song , Andrew Trotter , Jake Y. Chen

Multimodal neuroimaging analysis often involves complex, modality-specific preprocessing workflows that require careful configuration, quality control, and coordination across heterogeneous toolchains. Beyond preprocessing, downstream…

Artificial Intelligence · Computer Science 2026-05-08 Lujia Zhong , Yihao Xia , Jianwei Zhang , Shuo huang , Jiaxin Yue , Mingyang Xia , Yonggang Shi

Scientific workflows in computational chemistry and materials science typically involve multiple interdependent steps, such as model preparation, system construction, simulation execution, and data analysis, that researchers have refined…

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

High-dimensional decision-making tasks, such as business partner selection, involve evaluating large candidate pools with heterogeneous numerical, categorical, and textual features. While large language models (LLMs) offer strong in-context…

Multiagent Systems · Computer Science 2025-11-03 Lingyao Li , Haolun Wu , Zhenkun Li , Jiabei Hu , Yu Wang , Xiaoshan Huang , Wenyue Hua , Wenqian Wang

Transcriptome-wide association studies (TWAS) link genetic variation to complex traits by leveraging expression quantitative trait loci (eQTL) data. However, most implementations are typically limited to local (cis-acting) effects and fail…

Molecular Networks · Quantitative Biology 2025-12-09 Gutama Ibrahim Mohammad , Johan LM Björkegren , Tom Michoel

Automatic Multi-Agent Systems (MAS) generation has emerged as a promising paradigm for solving complex reasoning tasks. However, existing frameworks are fundamentally bottlenecked when applied to knowledge-intensive domains (e.g.,…

Artificial Intelligence · Computer Science 2026-03-24 Hehai Lin , Yu Yan , Zixuan Wang , Bo Xu , Sudong Wang , Weiquan Huang , Ruochen Zhao , Minzhi Li , Chengwei Qin

Large language models (LLMs) are being used in data science code generation tasks, but they often struggle with complex sequential tasks, leading to logical errors. Their application to geospatial data processing is particularly challenging…

Computers and Society · Computer Science 2024-10-28 Yuxing Chen , Weijie Wang , Sylvain Lobry , Camille Kurtz

Large language models (LLMs) has been widely used for automated negotiation, but their high computational cost and privacy risks limit deployment in privacy-sensitive, on-device settings such as mobile assistants or rescue robots. Small…

Artificial Intelligence · Computer Science 2026-04-14 Yunbo Long , Yuhan Liu , Liming Xu

Large Language Model (LLM)-based multi-agent systems (MAS) demonstrate remarkable potential for scientific discovery. Existing approaches, however, often automate scientific discovery using predefined workflows that lack rationality…

Machine Learning · Computer Science 2026-02-10 Yingming Pu , Tao Lin , Hongyu Chen

Translating single-cell RNA sequencing (scRNA-seq) data into mechanistic biological hypotheses remains a critical bottleneck, as agentic AI systems lack direct access to transcriptomic representations while expression foundation models…

Genomics · Quantitative Biology 2026-03-18 Omar Coser