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Related papers: Red Blood Cells as Elastic Surfaces

200 papers

We study a model for lipid-bilayer membrane vesicles exhibiting phase separation, incorporating a phase field together with membrane fluidity and bending elasticity. We prove the existence of a plethora of equilibria in the large,…

Analysis of PDEs · Mathematics 2015-09-18 Timothy J. Healey , Sanjay Dharmavaram

Understanding how red blood cell (RBC) suspensions navigate porous materials is critical for for both fundamental physiology, such as maternal-fetal exchange in the placenta, and transformative biomedical applications, including rapid,…

Soft Condensed Matter · Physics 2025-09-03 Sampad Laha , Ananta Kumar Nayak , Alexander Farutin , Suman Chakraborty , Chaouqi Misbah

In this work we propose a mathematical model that describes the orientation of ventricular cardiac fibers. These fibers are commonly computed as the normalized gradient of certain harmonic potentials, so our work consisted in finding the…

Numerical Analysis · Mathematics 2023-05-03 Nicolás A. Barnafi , Axel Osses

A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the…

Statistical Mechanics · Physics 2009-11-11 Grace Brannigan , Peter F. Philips , Frank L. H. Brown

Red blood cells (RBC) are known to form aggregates in the forms of rouleaux due to the presence of plasma proteins under physiological conditions. Rouleaux formation can be also induced in vitro by the addition of macromolecules to the RBC…

Medical Physics · Physics 2015-06-04 Patrick Steffen , Claude Verdier , Christian Wagner

Elastic light scattering by mature red blood cells (RBCs) was theoretically and experimentally analyzed with the discrete dipole approximation (DDA) and the scanning flow cytometry (SFC), respectively. SFC permits measurement of angular…

Lipid membranes are abundant in living organisms, where they constitute a surrounding shell for cells and their organelles. There are many circumstances in which the deformations of lipid membranes are involved in living cells: fusion and…

Soft Condensed Matter · Physics 2022-11-17 Konstantin V. Pinigin

We theoretically study the elastic deformation of a fluid membrane induced by an adhering spherical colloidal particle within the framework of a Helfrich energy. Based on a full optimization of the membrane shape we find a continuous…

Soft Condensed Matter · Physics 2009-11-07 Markus Deserno , Thomas Bickel

A phase-field model that takes into account the bending energy of fluid vesicles is presented. The Canham-Helfrich model is derived in the sharp-interface limit. A dynamic equation for the phase-field has been solved numerically to find…

Soft Condensed Matter · Physics 2007-05-23 F. Campelo , A. Hernandez-Machado

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) for different volume fractions in a wall-bounded, effectively inertialess, small amplitude oscillatory shear (SAOS) flow for a wide range of applied…

Fluid Dynamics · Physics 2024-04-08 Naoki Takeishi , Marco Edoardo Rosti , Naoto Yokoyama , Luca Brandt

Flexible rings and rectangle structures floating at the surface of water are prone to deflect under the action of surface pressure induced by the addition of surfactant molecules on the bath. While the frames of rectangles bend inward or…

Fluid Dynamics · Physics 2013-10-02 N. Adami , A. Delbos , B. Roman , J. Bico , H. Caps

Blebs are balloon-shaped membrane protrusions that form during many physiological processes. Using computer simulation of a particle-based model for self-assembled lipid bilayers coupled to an elastic meshwork, we investigated the phase…

Biological Physics · Physics 2015-05-30 Eric J. Spangler , Cameron W. Harvey , Joel D. Revalee , P. B. Sunil Kumar , Mohamed Laradji

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

Machine Learning · Computer Science 2020-10-12 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Manuel González-Hidalgo

A liquid foam in contact with a solid surface forms a two-dimensional foam on the surface. We derive the equilibrium equations for this 2D foam when the solid surface is curved and smooth, generalising the standard case of flat Hele Shaw…

Soft Condensed Matter · Physics 2009-11-11 M. Mancini , C. Oguey

We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determining the extent to which equilibrium elasticity theory can…

Subcellular Processes · Quantitative Biology 2012-02-22 Teresa Ruiz-Herrero , Enrique Velasco , Michael F. Hagan

We present a two dimensional model describing the elastic behaviour of the wall of a curved blood vessel. The wall has a laminate structure consisting of several anisotropic layers of varying thickness and is assumed to be much smaller in…

Tissues and Organs · Quantitative Biology 2017-08-18 Arpan Ghosh , Vladimir Kozlov , Sergey Nazarov , David Rule

Recent theoretical advances in elasticity of membranes following Helfrich's famous spontaneous curvature model are summarized in this review. The governing equations describing equilibrium configurations of lipid vesicles, lipid membranes…

Soft Condensed Matter · Physics 2017-07-27 Z. C. Tu , Z. C. Ou-Yang

The microvascular networks in the body of vertebrates consist of the smallest vessels such as arterioles, capillaries, and venules. The flow of RBCs through these networks ensures the gas exchange in as well as the transport of nutrients to…

Biological Physics · Physics 2021-02-26 A. Kihm , S. Quint , M. W. Laschke , M. D. Menger , T. John , L. Kaestner , C. Wagner

After a brief introduction to several variational problems in the study of shapes of thin thickness structures, we deal with variational problems on 2-dimensional surface in 3-dimensional Euclidian space by using exterior differential…

Mathematical Physics · Physics 2007-05-23 Z. C. Tu , Z. C. Ou-Yang

Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Annika Wong , Nantheera Anantrasirichai , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Attakorn Palasuwan , David Bull