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We consider the protein sequence engineering problem, which aims to find protein sequences with high fitness levels, starting from a given wild-type sequence. Directed evolution has been a dominating paradigm in this field which has an…

Machine Learning · Computer Science 2025-01-20 Yinkai Wang , Jiaxing He , Yuanqi Du , Xiaohui Chen , Jianan Canal Li , Li-Ping Liu , Xiaolin Xu , Soha Hassoun

Deploying large language model (LLM) inference at scale requires jointly selecting base models, provisioning heterogeneous GPUs, configuring parallelism, and distributing workloads under tight latency, accuracy, and budget constraints.…

Machine Learning · Computer Science 2026-04-10 Jiaming Cheng , Duong Tung Nguyen

Multi-objective optimization is now a core paradigm in engineering design and scientific discovery. Yet mainstream evolutionary frameworks, including \textit{pymoo}, still depend on imperative coding for problem definition, algorithm…

Software Engineering · Computer Science 2026-03-03 Thiago Santos , Sebastiao Xavier , Luiz Gustavo de Oliveira Carneiro , Gustavo de Souza

In the past few decades, many multiobjective evolutionary optimization algorithms (MOEAs) have been proposed to find a finite set of approximate Pareto solutions for a given problem in a single run, each with its own structure. However, in…

Neural and Evolutionary Computing · Computer Science 2024-04-30 Xi Lin , Xiaoyuan Zhang , Zhiyuan Yang , Qingfu Zhang

Multi-modal multi-objective optimization is to locate (almost) equivalent Pareto optimal solutions as many as possible. While decomposition-based evolutionary algorithms have good performance for multi-objective optimization, they are…

Neural and Evolutionary Computing · Computer Science 2020-10-01 Ryoji Tanabe , Hisao Ishibuchi

Large Language Models (LLMs) have demonstrated impressive capabilities in language processing, yet they often struggle with tasks requiring genuine visual spatial reasoning. In this paper, we introduce a novel two-stage training framework…

Computation and Language · Computer Science 2025-02-26 Alan Dao , Dinh Bach Vu

The integration of Large Language Models (LLMs) into optimization has created a powerful synergy, opening exciting research opportunities. This paper investigates how LLMs can enhance existing optimization algorithms. Using their…

Artificial Intelligence · Computer Science 2025-02-13 Camilo Chacón Sartori , Christian Blum

This paper introduces Multi-population Ensemble Genetic Programming (MEGP), a computational intelligence framework that integrates cooperative coevolution and the multiview learning paradigm to address classification challenges in…

Neural and Evolutionary Computing · Computer Science 2025-09-25 Mohammad Sadegh Khorshidi , Navid Yazdanjue , Hassan Gharoun , Mohammad Reza Nikoo , Fang Chen , Amir H. Gandomi

Large language models (LLMs) based on transformers have made significant strides in recent years, the success of which is driven by scaling up their model size. Despite their high algorithmic performance, the computational and memory…

Machine Learning · Computer Science 2024-04-30 Ranggi Hwang , Jianyu Wei , Shijie Cao , Changho Hwang , Xiaohu Tang , Ting Cao , Mao Yang

The integration of Large Language Models (LLMs) into evolutionary frameworks has established a new paradigm for automated heuristic discovery. Despite their promise, these methods typically search in the discrete space of program syntax,…

Artificial Intelligence · Computer Science 2026-05-19 Cheikh Ahmed , Mahdi Mostajabdaveh , Zirui Zhou

Optimization benchmarks play a fundamental role in assessing algorithm performance; however, existing artificial benchmarks often fail to capture the diversity and irregularity of real-world problem structures, while benchmarks derived from…

Neural and Evolutionary Computing · Computer Science 2026-01-26 Yuhiro Ono , Tomohiro Harada , Yukiya Miura

Quality-Diversity (QD) algorithms have recently gained traction as optimisation methods due to their effectiveness at escaping local optima and capability of generating wide-ranging and high-performing solutions. Recently, Multi-Objective…

Neural and Evolutionary Computing · Computer Science 2023-05-17 Hannah Janmohamed , Thomas Pierrot , Antoine Cully

The optimal assignment of Large Language Models (LLMs) to specialized roles in multi-agent systems is a significant challenge, defined by a vast combinatorial search space, expensive black-box evaluations, and an inherent trade-off between…

Multiagent Systems · Computer Science 2025-11-18 Antonio Sabbatella

Feature Engineering (FE) is pivotal in automated machine learning (AutoML) but remains a bottleneck for traditional methods, which operate within rigid search spaces and lack domain awareness. While Large Language Models (LLMs) offer a…

Machine Learning · Computer Science 2026-05-22 Beicheng Xu , Keyao Ding , Wei Liu , Yupeng Lu , Bin Cui

Large Language Models (LLMs) have achieved remarkable success across diverse applications, yet their deployment remains challenging due to substantial computational costs, memory requirements, and energy consumption. Recent empirical…

Machine Learning · Computer Science 2026-03-24 Kaito Tanaka , Masato Ito , Yuji Nishimura , Keisuke Matsuda , Aya Nakayama

Large language models (LLMs) achieve strong performance across a wide range of tasks but are highly sensitive to prompt design, motivating the need for automatic prompt optimization. Existing methods predominantly focus on performance…

Machine Learning · Computer Science 2026-05-20 Jan Büssing , Moritz Schlager , Timo Heiß , Tom Zehle , Matthias Feurer

Large Language Models (LLMs) exhibit strong potential in mathematical reasoning, yet their effectiveness is often limited by a shortage of high-quality queries. This limitation necessitates scaling up computational responses through…

Artificial Intelligence · Computer Science 2025-05-20 Jingyue Gao , Runji Lin , Keming Lu , Bowen Yu , Junyang Lin , Jianyu Chen

Multi-objective optimization problems (MOPs) require the simultaneous optimization of conflicting objectives. Real-world MOPs often exhibit complex characteristics, including high-dimensional decision spaces, many objectives, or…

Neural and Evolutionary Computing · Computer Science 2025-10-20 Haokai Hong , Liang Feng , Min Jiang , Kay Chen Tan

Multi-objective orienteering problems (MO-OPs) are classical multi-objective routing problems and have received a lot of attention in the past decades. This study seeks to solve MO-OPs through a problem-decomposition framework, that is, a…

Neural and Evolutionary Computing · Computer Science 2022-06-22 Wei Liu , Rui Wang , Tao Zhang , Kaiwen Li , Wenhua Li , Hisao Ishibuchi

Large Language Model-based Hyper Heuristic (LHH) has recently emerged as an efficient way for automatic heuristic design. However, most existing LHHs just perform well in optimizing a single function within a pre-defined solver. Their…

Artificial Intelligence · Computer Science 2026-04-15 Chuyang Xiang , Yichen Wei , Jiale Ma , Handing Wang , Junchi Yan
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