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DNA as a data storage medium has several advantages, including far greater data density compared to electronic media. We propose that schemes for data storage in the DNA of living organisms may benefit from studying the reconstruction…

Information Theory · Computer Science 2019-09-10 Yonatan Yehezkeally , Moshe Schwartz

We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing…

Information Theory · Computer Science 2015-05-12 S. M. Hossein Tabatabaei Yazdi , Yongbo Yuan , Jian Ma , Huimin Zhao , Olgica Milenkovic

We address the use of maximum distance separable (MDS) codes for distributed storage (DS) to enable efficient content delivery in wireless networks. Content is stored in a number of the mobile devices and can be retrieved from them using…

Information Theory · Computer Science 2016-08-30 Amina Piemontese , Alexandre Graell i Amat

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman

In this paper we define the overflow problem of a network coding storage system in which the encoding parameter and the storage parameter are mismatched. Through analyses and experiments, we first show the impacts of the overflow problem in…

Cryptography and Security · Computer Science 2017-02-20 Yu-Jia Chen , Li-Chun Wang

We study the problem of storing a data object in a set of data nodes that fail independently with given probabilities. Our problem is a natural generalization of a homogenous storage allocation problem where all the nodes had the same…

Information Theory · Computer Science 2012-02-09 Vasileios Ntranos , Giuseppe Caire , Alexandros G. Dimakis

The design of large libraries of oligonucleotides having constant GC-content and satisfying Hamming distance constraints between oligonucleotides and their Watson-Crick complements is important in reducing hybridization errors in DNA…

Information Theory · Computer Science 2008-03-27 Yeow Meng Chee , San Ling

Storing data in DNA is being explored as an efficient solution for archiving and in-object storage. Synthesis time and cost remain challenging, significantly limiting some applications at this stage. In this paper we investigate efficient…

Information Theory · Computer Science 2024-12-10 Amit Zrihan , Eitan Yaakobi , Zohar Yakhini

The growing use of deep neural networks in safety-critical applications makes it necessary to carry out adequate testing to detect and correct any incorrect behavior for corner case inputs before they can be actually used. Deep neural…

Software Engineering · Computer Science 2019-02-19 Jasmine Sekhon , Cody Fleming

Distributed storage systems often introduce redundancy to increase reliability. When coding is used, the repair problem arises: if a node storing encoded information fails, in order to maintain the same level of reliability we need to…

Information Theory · Computer Science 2010-04-27 Alexandros G. Dimakis , Kannan Ramchandran , Yunnan Wu , Changho Suh

Deep neural networks (DNN) are increasingly applied in safety-critical systems, e.g., for face recognition, autonomous car control and malware detection. It is also shown that DNNs are subject to attacks such as adversarial perturbation and…

Machine Learning · Computer Science 2019-11-15 Yizhen Dong , Peixin Zhang , Jingyi Wang , Shuang Liu , Jun Sun , Jianye Hao , Xinyu Wang , Li Wang , Jin Song Dong , Dai Ting

The ability to store data in the DNA of a living organism has applications in a variety of areas including synthetic biology and watermarking of patented genetically-modified organisms. Data stored in this medium is subject to errors…

Information Theory · Computer Science 2016-11-17 Siddharth Jain , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

DNA strings and their properties are widely studied since last 20 years due to its applications in DNA computing. In this area, one designs a set of DNA strings (called DNA code) which satisfies certain thermodynamic and combinatorial…

Information Theory · Computer Science 2025-10-03 Krishna Gopal Benerjee , Manish K Gupta

Data storage is one of the main computing issues of this century. Not only storage devices are converging to strict physical limits, but also the amount of data generated by users is growing at an unbelievable rate. To face these…

Cryptography and Security · Computer Science 2020-09-29 Federico Tavella , Alberto Giaretta , Mauro Conti , Sasitharan Balasubramaniam

Genome sequencing is the basis for many modern biological and medicinal studies. With recent technological advances, metagenomics has become a problem of interest. This problem entails the analysis and reconstruction of multiple DNA…

Probability · Mathematics 2022-01-14 Marlee Herring

Motivated by applications to DNA storage, we study reconstruction and list-reconstruction schemes for integer vectors that suffer from limited-magnitude errors. We characterize the asymptotic size of the intersection of error balls in…

Information Theory · Computer Science 2021-08-24 Hengjia Wei , Moshe Schwartz

A number of methods have been proposed over the last decade for encoding information using deoxyribonucleic acid (DNA), giving rise to the emerging area of DNA data embedding. Since a DNA sequence is conceptually equivalent to a sequence of…

Information Theory · Computer Science 2014-10-09 Félix Balado

We address the challenge of optimizing the capacity-achieving input distribution for a multinomial channel under the constraint of limited input support size, which is a crucial aspect in the design of DNA storage systems. We propose an…

Information Theory · Computer Science 2025-01-28 Adir Kobovich , Eitan Yaakobi , Nir Weinberger

Subspace codes form the appropriate mathematical setting for investigating the Koetter-Kschischang model of fault-tolerant network coding. The Main Problem of Subspace Coding asks for the determination of a subspace code of maximum size…

Combinatorics · Mathematics 2014-08-07 Haiteng Liu , Thomas Honold

Recent experiments have demonstrated the feasibility of storing digital information in macromolecules such as DNA and protein. However, the DNA storage channel is prone to errors such as deletions, insertions, and substitutions. During the…

Information Theory · Computer Science 2024-10-22 Aryan Abbasian , Mahtab Mirmohseni , Masoumeh Nasiri Kenari