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Machine Learning has been applied to pathology images in research and clinical practice with promising outcomes. However, standard ML models often lack the rigorous evaluation required for clinical decisions. Machine learning techniques for…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Syed Ashar Javed , Dinkar Juyal , Zahil Shanis , Shreya Chakraborty , Harsha Pokkalla , Aaditya Prakash

Multiple instance learning (MIL) has been extensively applied to whole slide histopathology image (WSI) analysis. The existing aggregation strategy in MIL, which primarily relies on the first-order distance (e.g., mean difference) between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Yihang Chen , Tsai Hor Chan , Guosheng Yin , Yuming Jiang , Lequan Yu

We address the problem of \emph{instance label stability} in multiple instance learning (MIL) classifiers. These classifiers are trained only on globally annotated images (bags), but often can provide fine-grained annotations for image…

Computer Vision and Pattern Recognition · Computer Science 2017-03-16 Veronika Cheplygina , Lauge Sørensen , David M. J. Tax , Marleen de Bruijne , Marco Loog

Multiple Instance Learning (MIL) has garnered widespread attention in the field of Whole Slide Image (WSI) classification as it replaces pixel-level manual annotation with diagnostic reports as labels, significantly reducing labor costs.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Tianhang Nan , Hao Quan , Yong Ding , Xingyu Li , Kai Yang , Xiaoyu Cui

We propose a Multi-Instance-Learning (MIL) approach for weakly-supervised learning problems, where a training set is formed by bags (sets of feature vectors or instances) and only labels at bag-level are provided. Specifically, we consider…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Adria Ruiz , Ognjen Rudovic , Xavier Binefa , Maja Pantic

Despite being resource-intensive to train, 3D convolutional neural networks (CNNs) have been the standard approach to classify CT and MRI scans. Recent work suggests that deep multiple instance learning (MIL) may be a more efficient…

Machine Learning · Computer Science 2026-04-30 Ethan Harvey , Dennis Johan Loevlie , Amir Ali Satani , Wansu Chen , David M. Kent , Michael C. Hughes

Pre-trained encoders for offline feature extraction followed by multiple instance learning (MIL) aggregators have become the dominant paradigm in computational pathology (CPath), benefiting cancer diagnosis and prognosis. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Wenhao Tang , Rong Qin , Heng Fang , Fengtao Zhou , Hao Chen , Xiang Li , Ming-Ming Cheng

In recent years, there has been a rapid growth in the application of machine learning techniques that leverage aviation data collected from commercial airline operations to improve safety. Anomaly detection and predictive maintenance have…

Machine Learning · Statistics 2021-03-11 Marc-Henri Bleu-Laine , Tejas G. Puranik , Dimitri N. Mavris , Bryan Matthews

For a medical diagnosis, health professionals use different kinds of pathological ways to make a decision for medical reports in terms of patients medical condition. In the modern era, because of the advantage of computers and technologies,…

Machine Learning · Statistics 2021-06-08 Fahad B. Mostafa , Md Easin Hasan

Whole body magnetic resonance imaging (WB-MRI) is the recommended modality for diagnosis of multiple myeloma (MM). WB-MRI is used to detect sites of disease across the entire skeletal system, but it requires significant expertise and is…

The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Training deep learning models on medical datasets that perform well for all classes is a challenging task. It is often the case that a suboptimal performance is obtained on some classes due to the natural class imbalance issue that comes…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Suraj Kothawade , Atharv Savarkar , Venkat Iyer , Lakshman Tamil , Ganesh Ramakrishnan , Rishabh Iyer

To alleviate the cost of regression testing in continuous integration (CI), a large number of machine learning-based (ML-based) test case prioritization techniques have been proposed. However, it is yet unknown how they perform under the…

Software Engineering · Computer Science 2023-11-23 Yifan Zhao , Dan Hao , Lu Zhang

Multiple Instance Learning (MIL) is the leading approach for whole slide image (WSI) classification, enabling efficient analysis of gigapixel pathology slides. Recent work has introduced vision-language models (VLMs) into MIL pipelines to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Ngoc Bui Lam Quang , Nam Le Nguyen Binh , Thanh-Huy Nguyen , Le Thien Phuc Nguyen , Quan Nguyen , Ulas Bagci

Multiple instance learning (MIL) is the standard approach for whole-slide image (WSI) classification and survival prediction, where attention-based models ag gregate patch features into slide-level predictions. These models treat attention…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xiangyu Li , Ran Su

In many review classification applications, a fine-grained analysis of the reviews is desirable, because different segments (e.g., sentences) of a review may focus on different aspects of the entity in question. However, training supervised…

Machine Learning · Computer Science 2019-10-02 Giannis Karamanolakis , Daniel Hsu , Luis Gravano

The accurate evaluation of left atrial fibrosis via high-quality 3D Late Gadolinium Enhancement (LGE) MRI is crucial for atrial fibrillation management but is hindered by factors like patient movement and imaging variability. The pursuit of…

Curriculum learning strategies in prior multi-task learning approaches arrange datasets in a difficulty hierarchy either based on human perception or by exhaustively searching the optimal arrangement. However, human perception of difficulty…

Machine Learning · Computer Science 2022-05-30 Neeraj Varshney , Swaroop Mishra , Chitta Baral