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Chronic neck pain is a leading cause of disability worldwide, and current treatment selection remains largely trial and error. We present a machine learning framework that uses electroencephalography to predict treatment efficacy in…

Quantitative Methods · Quantitative Biology 2026-05-19 Xiru Wang , Aiden Li , Hongzhao Tan , Stevie Foglia , Aimee Nelson , Zhen Gao

Neuroblastoma, adrenal-derived, is among the most common pediatric solid malignancies, characterized by significant clinical heterogeneity. Timely and accurate pathological diagnosis from hematoxylin and eosin-stained whole-slide images is…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Zhu Zhu , Shuo Jiang , Jingyuan Zheng , Yawen Li , Yifei Chen , Manli Zhao , Weizhong Gu , Feiwei Qin , Jinhu Wang , Gang Yu

Due to the significant resemblance in visual appearance, pill misuse is prevalent and has become a critical issue, responsible for one-third of all deaths worldwide. Pill identification, thus, is a crucial concern needed to be investigated…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Anh Duy Nguyen , Huy Hieu Pham , Huynh Thanh Trung , Quoc Viet Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

Accurately predicting drug-drug interactions (DDIs) is crucial for pharmaceutical research and clinical safety. Recent deep learning models often suffer from high computational costs and limited generalization across datasets. In this…

Biomolecules · Quantitative Biology 2025-04-01 Manel Gil-Sorribes , Alexis Molina

Magnetic resonance imaging (MRI) relies on radiofrequency (RF) excitation of proton spin. Clinical diagnosis requires a comprehensive collation of biophysical data via multiple MRI contrasts, acquired using a series of RF sequences that…

Medical Physics · Physics 2025-12-24 Dinor Nagar , Moritz Zaiss , Or Perlman

The escalating drug addiction crisis in the United States underscores the urgent need for innovative therapeutic strategies. This study embarked on an innovative and rigorous strategy to unearth potential drug repurposing candidates for…

Biomolecules · Quantitative Biology 2023-12-05 Hongyan Du , Guo-Wei Wei , Tingjun Hou

Previous research has revealed the potential of large language models (LLMs) to support cognitive reframing therapy; however, their focus was primarily on text-based methods, often overlooking the importance of non-verbal evidence crucial…

Computation and Language · Computer Science 2025-02-12 Subin Kim , Hoonrae Kim , Heejin Do , Gary Geunbae Lee

Medical imaging technologies have undergone extensive development, enabling non-invasive visualization of clinical information. The traditional review of medical images by clinicians remains subjective, time-consuming, and prone to human…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Elizaveta Lavrova , Henry C. Woodruff , Hamza Khan , Eric Salmon , Philippe Lambin , Christophe Phillips

Psychedelics, such as psilocybin, reorganise large-scale brain connectivity, yet how these changes are reflected across electrophysiological (electroencephalogram, EEG) and haemodynamic (functional magnetic resonance imaging, fMRI) networks…

Neurons and Cognition · Quantitative Biology 2025-11-25 Sin-Yee Yap , Fuad Noman , Junn Yong Loo , Devon Stoliker , Moein Khajehnejad , Raphaël C. -W. Phan , David L. Dowe , Adeel Razi , Chee-Ming Ting

Contrastive Language-Image Pretraining (CLIP) has achieved remarkable success, leading to rapid advancements in multimodal studies. However, CLIP faces a notable challenge in terms of inefficient data utilization. It relies on a single…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Yu Zhang , Qi Zhang , Zixuan Gong , Yiwei Shi , Yepeng Liu , Duoqian Miao , Yang Liu , Ke Liu , Kun Yi , Wei Fan , Liang Hu , Changwei Wang

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to…

Machine Learning · Computer Science 2019-10-22 David Wood , James Cole , Thomas Booth

Vision-Language Models (VLMs) trained via contrastive learning have achieved notable success in natural image tasks. However, their application in the medical domain remains limited due to the scarcity of openly accessible, large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Muhammad Uzair Khattak , Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

The performance of existing supervised neuron segmentation methods is highly dependent on the number of accurate annotations, especially when applied to large scale electron microscopy (EM) data. By extracting semantic information from…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Yinda Chen , Wei Huang , Shenglong Zhou , Qi Chen , Zhiwei Xiong

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Deep learning associated with neurological signals is poised to drive major advancements in diverse fields such as medical diagnostics, neurorehabilitation, and brain-computer interfaces. The challenge in harnessing the full potential of…

Signal Processing · Electrical Eng. & Systems 2024-07-08 Di Wu , Siyuan Li , Jie Yang , Mohamad Sawan

Functional MRI (fMRI) is a powerful technique that has allowed us to characterize visual cortex responses to stimuli, yet such experiments are by nature constructed based on a priori hypotheses, limited to the set of images presented to the…

Neurons and Cognition · Quantitative Biology 2021-05-18 Zijin Gu , Keith W. Jamison , Meenakshi Khosla , Emily J. Allen , Yihan Wu , Thomas Naselaris , Kendrick Kay , Mert R. Sabuncu , Amy Kuceyeski

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Drug discovery projects entail cycles of design, synthesis, and testing that yield a series of chemically related small molecules whose properties, such as binding affinity to a given target protein, are progressively tailored to a…

Machine Learning · Computer Science 2020-02-10 Paul Maragakis , Hunter Nisonoff , Brian Cole , David E. Shaw

Visual decoding of neurophysiological signals is a critical challenge for brain-computer interfaces (BCIs) and computational neuroscience. However, current approaches are often constrained by the systematic and stochastic gaps between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Feixue Shao , Guangze Shi , Xueyu Liu , Yongfei Wu , Mingqiang Wei , Jianan Zhang , Jianbo Lu , Guiying Yan , Weihua Yang