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Multimodal contrastive pretraining has been used to train multimodal representation models, such as CLIP, on large amounts of paired image-text data. However, previous studies have revealed that such models are vulnerable to backdoor…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Hritik Bansal , Nishad Singhi , Yu Yang , Fan Yin , Aditya Grover , Kai-Wei Chang

Medical image understanding plays a crucial role in enabling automated diagnosis and data-driven clinical decision support. However, its progress is impeded by two primary challenges: the limited availability of high-quality annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tianchen Fang , Guiru Liu

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

Data-driven approaches for depression diagnosis have emerged as a significant research focus in neuromedicine, driven by the development of relevant datasets. Recently, graph neural network (GNN)-based models have gained widespread adoption…

Machine Learning · Computer Science 2025-05-01 Chengkai Yang , Xingping Dong , Xiaofen Zong

Early detection of eye diseases like glaucoma, macular degeneration, and diabetic retinopathy is crucial for preventing vision loss. While artificial intelligence (AI) foundation models hold significant promise for addressing these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Danli Shi , Weiyi Zhang , Jiancheng Yang , Siyu Huang , Xiaolan Chen , Mayinuer Yusufu , Kai Jin , Shan Lin , Shunming Liu , Qing Zhang , Mingguang He

Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional…

Machine Learning · Computer Science 2024-11-25 Anwar Said , Roza G. Bayrak , Tyler Derr , Mudassir Shabbir , Daniel Moyer , Catie Chang , Xenofon Koutsoukos

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Accurate prediction of enzyme kinetic parameters is crucial for drug discovery, metabolic engineering, and synthetic biology applications. Current computational approaches face limitations in capturing complex enzyme-substrate interactions…

Biomolecules · Quantitative Biology 2025-12-02 Anas Aziz Khan , Md Shah Fahad , Priyanka , Ramesh Chandra , Guransh Singh

Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and…

Biomolecules · Quantitative Biology 2023-09-26 Srilekha Mamidala

Drug Mechanism of Action (MoA) mainly investigates how drug molecules interact with cells, which is crucial for drug discovery and clinical application. Recently, deep learning models have been used to recognize MoA by relying on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Fengqian Pang , Chunyue Lei , Hongfei Zhao , Chenghao Liu , Zhiqiang Xing , Huafeng Wang , Chuyang Ye

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Vision-language foundation models have emerged as powerful general-purpose representation learners with strong potential for multimodal understanding, but their deterministic embeddings often fail to provide the reliability required for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Ahmad Elallaf , Yu Zhang , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

Multimodal multilabel classification (MMC) is a challenging task that aims to design a learning algorithm to handle two data sources, the image and text, and learn a comprehensive semantic feature presentation across the modalities. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Yanming Guo

Emotion recognition is an important research direction in artificial intelligence, helping machines understand and adapt to human emotional states. Multimodal electrophysiological(ME) signals, such as EEG, GSR, respiration(Resp), and…

Multimedia · Computer Science 2023-08-07 Yunfei Guo , Tao Zhang , Wu Huang

Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to…

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Automatic generation of radiology reports seeks to reduce clinician workload while improving documentation consistency. Existing methods that adopt encoder-decoder or retrieval-augmented pipelines achieve progress in fluency but remain…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Rong Fu , Yiqing Lyu , Chunlei Meng , Muge Qi , Yabin Jin , Qi Zhao , Li Bao , Juntao Gao , Fuqian Shi , Nilanjan Dey , Wei Luo , Simon Fong

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

The scarcity of annotated data has sparked significant interest in unsupervised pre-training methods that leverage medical reports as auxiliary signals for medical visual representation learning. However, existing research overlooks the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Zhe Li , Laurence T. Yang , Bocheng Ren , Xin Nie , Zhangyang Gao , Cheng Tan , Stan Z. Li

Low back pain affects millions worldwide, driving the need for robust diagnostic models that can jointly analyze complex medical images and accompanying text reports. We present LumbarCLIP, a novel multimodal framework that leverages…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Thanh Binh Le , Hoang Nhat Khang Vo , Tan-Ha Mai , Trong Nhan Phan