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Non-muscle-invasive bladder cancer (NMIBC) is a relentless challenge in oncology, with recurrence rates soaring as high as 70-80%. Each recurrence triggers a cascade of invasive procedures, lifelong surveillance, and escalating healthcare…

Machine Learning · Computer Science 2025-05-02 Saram Abbas , Naeem Soomro , Rishad Shafik , Rakesh Heer , Kabita Adhikari

Notorious for its 70-80% recurrence rate, Non-muscle-invasive Bladder Cancer (NMIBC) imposes a significant human burden and is one of the costliest cancers to manage. Current tools for predicting NMIBC recurrence rely on scoring systems…

Machine Learning · Computer Science 2024-12-23 Saram Abbas , Rishad Shafik , Naeem Soomro , Rakesh Heer , Kabita Adhikari

We investigated the data-driven relationship between features in the tumor microenvironment (TME) and the overall and 5-year survival in triple-negative breast cancer (TNBC) and non-TNBC (NTNBC) patients by using Explainable Artificial…

Neural network-based models have found wide use in automatic long-term electrocardiogram (ECG) analysis. However, such black box models are inadequate for analysing physiological signals where credibility and interpretability are crucial.…

Signal Processing · Electrical Eng. & Systems 2023-01-25 Jinbao Zhang , Xuan Zhang , Lei Jiao , Ole-Christoffer Granmo , Yongjun Qian , Fan Pan

The Tsetlin Machine (TM) is a novel machine learning paradigm that employs finite-state automata for learning and utilizes propositional logic to represent patterns. Due to its simplistic approach, TMs are inherently more interpretable than…

Machine Learning · Computer Science 2025-10-03 Mayur Kishor Shende , Ole-Christoffer Granmo , Runar Helin , Vladimir I. Zadorozhny , Rishad Shafik

Thyroid carcinoma, a significant yet often controllable cancer, has seen a rise in cases, largely due to advancements in diagnostic methods. Differentiated thyroid cancer (DTC), which includes papillary and follicular varieties, is…

Machine Learning · Computer Science 2025-05-06 Mohammad Al-Sayed Ahmad , Jude Haddad

Bladder cancer ranks within the top 10 most diagnosed cancers worldwide and is among the most expensive cancers to treat due to the high recurrence rates which require lifetime follow-ups. The primary tool for diagnosis is cystoscopy, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Meryem Amaouche , Ouassim Karrakchou , Mounir Ghogho , Anouar El Ghazzaly , Mohamed Alami , Ahmed Ameur

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Bladder cancer is one of the most prevalent malignancies worldwide, with a recurrence rate of up to 78%, necessitating accurate post-operative monitoring for effective patient management. Multi-sequence contrast-enhanced MRI is commonly…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xueyang Li , Zongren Wang , Yuliang Zhang , Zixuan Pan , Yu-Jen Chen , Nishchal Sapkota , Gelei Xu , Danny Z. Chen , Yiyu Shi

Medical applications challenge today's text categorization techniques by demanding both high accuracy and ease-of-interpretation. Although deep learning has provided a leap ahead in accuracy, this leap comes at the sacrifice of…

In oncology, recurrence after treatment is one of the major challenges, related to patients' survival and quality of life. Conventionally, prediction of cancer relapse has always relied on clinical observation with statistical model…

Machine Learning · Computer Science 2025-02-25 Muhammad Umer Qayyum , Muhammad Fahad , Nasrullah Abbasi

The Tsetlin Machine (TM) is a machine learning algorithm founded on the classical Tsetlin Automaton (TA) and game theory. It further leverages frequent pattern mining and resource allocation principles to extract common patterns in the…

Machine Learning · Computer Science 2020-04-08 Saeed Rahimi Gorji , Ole-Christoffer Granmo , Sondre Glimsdal , Jonathan Edwards , Morten Goodwin

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…

Quantitative Methods · Quantitative Biology 2025-05-23 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Background Predicting overall survival (OS) in non-small cell lung cancer (NSCLC) is essential for clinical decision-making and drug development. While tumor and blood test markers kinetics are intrinsically linked, their joint dynamics and…

Quantitative Methods · Quantitative Biology 2026-01-19 Ruben Taieb , René Bruno , Pascal Chanu , Jin Yan Jin , Sébastien Benzekry

Convolutional neural networks (CNNs) have obtained astounding successes for important pattern recognition tasks, but they suffer from high computational complexity and the lack of interpretability. The recent Tsetlin Machine (TM) attempts…

Machine Learning · Computer Science 2019-12-30 Ole-Christoffer Granmo , Sondre Glimsdal , Lei Jiao , Morten Goodwin , Christian W. Omlin , Geir Thore Berge

Clinical trials play an important role in cancer care and research, yet participation rates remain low. We developed MSK-MATCH (Memorial Sloan Kettering Multi-Agent Trial Coordination Hub), an AI system for automated eligibility screening…

Machine Learning · Computer Science 2025-11-11 Jacob T. Rosenthal , Emma Hahesy , Sulov Chalise , Menglei Zhu , Mert R. Sabuncu , Lior Z. Braunstein , Anyi Li

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Objective: Accurate visual classification of bladder tissue during Trans-Urethral Resection of Bladder Tumor (TURBT) procedures is essential to improve early cancer diagnosis and treatment. During TURBT interventions, White Light Imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Jorge F. Lazo , Benoit Rosa , Michele Catellani , Matteo Fontana , Francesco A. Mistretta , Gennaro Musi , Ottavio de Cobelli , Michel de Mathelin , Elena De Momi

Background: Stratifying cancer patients according to risk of relapse can personalize their care. In this work, we provide an answer to the following research question: How to utilize machine learning to estimate probability of relapse in…

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