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The ability to rapidly develop materials with desired properties has a transformative impact on a broad range of emerging technologies. In this work, we introduce a new framework based on the diffusion model, a recent generative machine…

Synthesizing fully developed three-dimensional turbulent velocity fields remains a long-standing problem in fluid mechanics and an open challenge for generative modeling. The difficulty arises from the coexistence of extreme dimensionality,…

Fluid Dynamics · Physics 2026-03-16 Tianyi Li , Michele Buzzicotti , Fabio Bonaccorso , Luca Biferale

We tackle the dual challenges of video understanding and controllable video generation within a unified diffusion framework. Our key insights are two-fold: geometry-only cues (e.g., depth, edges) are insufficient: they specify layout but…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Dianbing Xi , Jiepeng Wang , Yuanzhi Liang , Xi Qiu , Jialun Liu , Hao Pan , Yuchi Huo , Rui Wang , Haibin Huang , Chi Zhang , Xuelong Li

De novo crystal generation seeks to discover materials that are not merely realistic, but also stable and novel. However, most existing generative models are trained to maximize the likelihood of observed crystals, which encourages samples…

Diffusion-based models demonstrate impressive generation capabilities. However, they also have a massive number of parameters, resulting in enormous model sizes, thus making them unsuitable for deployment on resource-constraint devices.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Avideep Mukherjee , Soumya Banerjee , Piyush Rai , Vinay P. Namboodiri

Inverse design problems are common in engineering and materials science. The forward direction, i.e., computing output quantities from design parameters, typically requires running a numerical simulation, such as a FEM, as an intermediate…

Machine Learning · Computer Science 2026-02-18 Jens U. Kreber , Christian Weißenfels , Joerg Stueckler

Generative modeling has emerged as a promising approach for crystal structure discovery. However, existing LLM-based generative models struggle with low-level atomic precision, while diffusion-based methods fall short in integrating…

Artificial Intelligence · Computer Science 2026-05-18 Yuyang Wu , Stefano Falletta , Delia McGrath , Sherry Yang

Spatial gradients of diffusible signalling molecules play crucial roles in controlling diverse cellular behaviour such as cell differentiation, tissue patterning and chemotaxis. In this paper, we report the design and testing of a…

Quantitative Methods · Quantitative Biology 2016-12-15 Yasushi Saka , Murray MacPherson , Claudiu V. Giuraniuc

Self-supervised neural language models have recently achieved unprecedented success, from natural language processing to learning the languages of biological sequences and organic molecules. These models have demonstrated superior…

Generative modeling of crystalline materials using diffusion models presents a series of challenges: the data distribution is characterized by inherent symmetries and involves multiple modalities, with some defined on specific manifolds.…

Generative models trained at scale can now produce text, video, and more recently, scientific data such as crystal structures. In applications of generative approaches to materials science, and in particular to crystal structures, the…

Generative models hold the promise of significantly expediting the materials design process when compared to traditional human-guided or rule-based methodologies. However, effectively generating high-quality periodic structures of materials…

Materials Science · Physics 2024-08-15 Anshuman Sinha , Shuyi Jia , Victor Fung

The three-dimensional (3D) microstructures of polycrystalline materials exert a critical influence on their mechanical and physical properties. Realistic, controllable construction of these microstructures is a key step toward elucidating…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Chi Chen , Tianle Jiang , Xiaodong Wei , Yanming Wang

We present CrystalDiT, a diffusion transformer for crystal structure generation that achieves state-of-the-art performance by challenging the trend of architectural complexity. Instead of intricate, multi-stream designs, CrystalDiT employs…

Machine Learning · Computer Science 2026-01-01 Xiaohan Yi , Guikun Xu , Xi Xiao , Zhong Zhang , Liu Liu , Yatao Bian , Peilin Zhao

Diffusion probabilistic models (DPMs) have become a popular approach to conditional generation, due to their promising results and support for cross-modal synthesis. A key desideratum in conditional synthesis is to achieve high…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Ye Zhu , Yu Wu , Kyle Olszewski , Jian Ren , Sergey Tulyakov , Yan Yan

Crystal generative models have shown rapid progress for accelerating the discovery of bulk, periodic materials. However, many material systems such as 2D superconductors, thin film semiconductors, and catalytic surfaces are diperiodic,…

Materials Science · Physics 2026-05-12 Rees Chang , Andrew Novick , Ryan P Adams , Elif Ertekin

Latest methods for visual counterfactual explanations (VCE) harness the power of deep generative models to synthesize new examples of high-dimensional images of impressive quality. However, it is currently difficult to compare the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-14 Philipp Vaeth , Alexander M. Fruehwald , Benjamin Paassen , Magda Gregorova

The generation and preservation of complex quantum states against environmental noise are paramount challenges in advancing continuous-variable (CV) quantum information processing. This paper introduces a novel framework based on…

Quantum Physics · Physics 2025-06-25 Haitao Huang , Chuangtao Chen , Qinglin Zhao

Single-crystal X-ray diffraction (SC-XRD) is the gold standard technique to characterize crystal structures in solid state. Despite significant advances in automation for structure solution, the refinement stage still depends heavily on…

Materials Science · Physics 2025-12-04 Wen-Lin Luo , Yi Yuan , Cheng-Hui Li , Yue Zhao , Jing-Lin Zuo

Generative models based on generative adversarial networks (GANs) and variational autoencoders (VAEs) have been widely studied in the fields of image generation, speech generation, and drug discovery, but, only a few studies have focused on…

Machine Learning · Computer Science 2019-10-28 Yoshihide Sawada , Koji Morikawa , Mikiya Fujii