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Large language models generate fluent texts and can follow natural language instructions to solve a wide range of tasks without task-specific training. Nevertheless, it is notoriously difficult to control their generation to satisfy the…

Computation and Language · Computer Science 2023-06-09 Wangchunshu Zhou , Yuchen Eleanor Jiang , Ethan Wilcox , Ryan Cotterell , Mrinmaya Sachan

Powerful generative models have led to recent progress in question generation (QG). However, it is difficult to measure advances in QG research since there are no standardized resources that allow a uniform comparison among approaches. In…

Computation and Language · Computer Science 2023-01-03 Asahi Ushio , Fernando Alva-Manchego , Jose Camacho-Collados

We tackle the task of conditional music generation. We introduce MusicGen, a single Language Model (LM) that operates over several streams of compressed discrete music representation, i.e., tokens. Unlike prior work, MusicGen is comprised…

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

Conversational agents have become an integral part of the general population for simple task enabling situations. However, these systems are yet to have any social impact on the diverse and minority population, for example, helping people…

Computation and Language · Computer Science 2021-12-07 Shachi H Kumar , Hsuan Su , Ramesh Manuvinakurike , Saurav Sahay , Lama Nachman

Diffusion models have achieved great success in modeling continuous data modalities such as images, audio, and video, but have seen limited use in discrete domains such as language. Recent attempts to adapt diffusion to language have…

Computation and Language · Computer Science 2023-11-08 Justin Lovelace , Varsha Kishore , Chao Wan , Eliot Shekhtman , Kilian Q. Weinberger

Generative Artificial Intelligence (AI) models such as OpenAI's ChatGPT have the potential to revolutionize Statistical Process Control (SPC) practice, learning, and research. However, these tools are in the early stages of development and…

Machine Learning · Computer Science 2023-06-19 Fadel M. Megahed , Ying-Ju Chen , Joshua A. Ferris , Sven Knoth , L. Allison Jones-Farmer

While recent advancements in speech language models have achieved significant progress, they face remarkable challenges in modeling the long acoustic sequences of neural audio codecs. In this paper, we introduce \textbf{G}enerative…

Computation and Language · Computer Science 2024-11-04 Yongxin Zhu , Dan Su , Liqiang He , Linli Xu , Dong Yu

Undirected neural sequence models such as BERT (Devlin et al., 2019) have received renewed interest due to their success on discriminative natural language understanding tasks such as question-answering and natural language inference. The…

Machine Learning · Computer Science 2020-02-10 Elman Mansimov , Alex Wang , Sean Welleck , Kyunghyun Cho

Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and function. They thus open the possibility…

Biomolecules · Quantitative Biology 2024-12-30 Damiano Sgarbossa , Umberto Lupo , Anne-Florence Bitbol

Gene regulation is a dynamic process that connects genotype and phenotype. Given the difficulty of physically mapping mammalian gene circuitry, we require new computational methods to learn regulatory rules. Natural language is a valuable…

Quantitative Methods · Quantitative Biology 2022-10-27 William Connell , Umair Khan , Michael J. Keiser

Inspired by the recent success of large language models (LLMs) like ChatGPT, researchers start to explore the adoption of LLMs for agile hardware design, such as generating design RTL based on natural-language instructions. However, in…

Machine Learning · Computer Science 2023-11-14 Yao Lu , Shang Liu , Qijun Zhang , Zhiyao Xie

Large language models (LLMs) successfully model natural language from vast amounts of text without the need for explicit supervision. In this paper, we investigate the efficacy of LLMs in modeling passwords. We present PassGPT, a LLM…

Computation and Language · Computer Science 2023-06-16 Javier Rando , Fernando Perez-Cruz , Briland Hitaj

Generating realistic and diverse trajectories is a critical challenge in autonomous driving simulation. While Large Language Models (LLMs) show promise, existing methods often rely on structured data like vectorized maps, which fail to…

Artificial Intelligence · Computer Science 2026-03-06 Mingxuan Mu , Guo Yang , Lei Chen , Ping Wu , Jianxun Cui

Antibody therapeutics are among the most successful modern medicines, yet computationally designing antibodies with desirable binding and developability properties remains challenging. While protein language models (pLMs) have emerged as…

Machine Learning · Computer Science 2026-05-11 Justin Sanders , Luca Giancardo , Lan Guo , Yue Zhao , Kemal Sonmez , Nina Cheng , Melih Yilmaz

Can we leverage LLMs to model the process of discovering novel language model (LM) architectures? Inspired by real research, we propose a multi-agent LLM approach that simulates the conventional stages of research, from ideation and…

Artificial Intelligence · Computer Science 2025-06-26 Junyan Cheng , Peter Clark , Kyle Richardson

Controllable text generation is a growing field within natural language generation (NLG) that focuses on producing text that meets specific constraints in real-world applications. Previous approaches, such as plug-and-play controllers…

Computation and Language · Computer Science 2024-02-07 Hao Wang , Lei Sha

Although traditional statistical techniques and machine learning methods have contributed significantly to genetics and, in particular, inherited disease diagnosis, they often struggle with complex, high-dimensional data, a challenge now…

Machine Learning · Computer Science 2025-08-29 Anton Changalidis , Yury Barbitoff , Yulia Nasykhova , Andrey Glotov

Building a general-purpose task model similar to ChatGPT has been an important research direction for gene large language models. Instruction fine-tuning is a key component in building ChatGPT, but existing instructions are primarily based…

Genomics · Quantitative Biology 2024-12-03 Wang Liang

Random Number Generation Tasks (RNGTs) are used in psychology for examining how humans generate sequences devoid of predictable patterns. By adapting an existing human RNGT for an LLM-compatible environment, this preliminary study tests…

Artificial Intelligence · Computer Science 2024-08-21 Rachel M. Harrison
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