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Large Language Models (LLMs) are widely used for tasks such as natural language and code generation, but their outputs often suffer from issues like hallucination, toxicity, and incorrect results. Current libraries for structured LLM…

Software Engineering · Computer Science 2025-03-04 Shubham Ugare , Rohan Gumaste , Tarun Suresh , Gagandeep Singh , Sasa Misailovic

The Generative Pre-trained Transformer (GPT) represents a notable breakthrough in the domain of natural language processing, which is propelling us toward the development of machines that can understand and communicate using language in a…

Self-supervised neural language models have recently found wide applications in generative design of organic molecules and protein sequences as well as representation learning for downstream structure classification and functional…

Materials Science · Physics 2022-09-21 Lai Wei , Nihang Fu , Yuqi Song , Qian Wang , Jianjun Hu

Large transformer-based language models (LMs) trained on huge text corpora have shown unparalleled generation capabilities. However, controlling attributes of the generated language (e.g. switching topic or sentiment) is difficult without…

Computation and Language · Computer Science 2020-03-04 Sumanth Dathathri , Andrea Madotto , Janice Lan , Jane Hung , Eric Frank , Piero Molino , Jason Yosinski , Rosanne Liu

Cross-domain natural language generation (NLG) is still a difficult task within spoken dialogue modelling. Given a semantic representation provided by the dialogue manager, the language generator should generate sentences that convey…

Computation and Language · Computer Science 2018-12-24 Bo-Hsiang Tseng , Florian Kreyssig , Pawel Budzianowski , Inigo Casanueva , Yen-Chen Wu , Stefan Ultes , Milica Gasic

Generic generation and manipulation of text is challenging and has limited success compared to recent deep generative modeling in visual domain. This paper aims at generating plausible natural language sentences, whose attributes are…

Machine Learning · Computer Science 2018-09-14 Zhiting Hu , Zichao Yang , Xiaodan Liang , Ruslan Salakhutdinov , Eric P. Xing

This paper presents an innovative exploration of the application potential of large language models (LLM) in addressing the challenging task of automatically generating behavior trees (BTs) for complex tasks. The conventional manual BT…

Computation and Language · Computer Science 2024-01-17 Fu Li , Xueying Wang , Bin Li , Yunlong Wu , Yanzhen Wang , Xiaodong Yi

Since the completion of the human genome sequencing project in 2001, significant progress has been made in areas such as gene regulation editing and protein structure prediction. However, given the vast amount of genomic data, the segments…

Other Quantitative Biology · Quantitative Biology 2025-01-29 Wang Liang

Controllable Text Generation (CTG) has obtained great success due to its fine-grained generation ability obtained by focusing on multiple attributes. However, most existing CTG researches overlook how to utilize the attribute entanglement…

Computation and Language · Computer Science 2022-11-01 Shulin Huang , Shirong Ma , Yinghui Li , Yangning Li , Shiyang Lin , Hai-Tao Zheng , Ying Shen

The GPT (Generative Pre-trained Transformer) language models are an artificial intelligence and natural language processing technology that enables automatic text generation. There is a growing interest in applying GPT language models to…

Computers and Society · Computer Science 2024-03-25 Manuel de Buenaga , Francisco Javier Bueno

We investigate large-scale latent variable models (LVMs) for neural story generation -- an under-explored application for open-domain long text -- with objectives in two threads: generation effectiveness and controllability. LVMs,…

Computation and Language · Computer Science 2021-07-09 Le Fang , Tao Zeng , Chaochun Liu , Liefeng Bo , Wen Dong , Changyou Chen

Large language models (LLMs) have been recently leveraged as training data generators for various natural language processing (NLP) tasks. While previous research has explored different approaches to training models using generated data,…

Computation and Language · Computer Science 2023-10-19 Yue Yu , Yuchen Zhuang , Jieyu Zhang , Yu Meng , Alexander Ratner , Ranjay Krishna , Jiaming Shen , Chao Zhang

In the rapidly evolving landscape of genomics, deep learning has emerged as a useful tool for tackling complex computational challenges. This review focuses on the transformative role of Large Language Models (LLMs), which are mostly based…

Existing PLMs generate protein sequences based on a single-condition constraint from a specific modality, struggling to simultaneously satisfy multiple constraints across different modalities. In this work, we introduce CFP-Gen, a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Junbo Yin , Chao Zha , Wenjia He , Chencheng Xu , Xin Gao

In recent years, natural language processing (NLP) models have demonstrated remarkable capabilities in various domains beyond traditional text generation. In this work, we introduce PeptideGPT, a protein language model tailored to generate…

Machine Learning · Computer Science 2024-10-28 Aayush Shah , Chakradhar Guntuboina , Amir Barati Farimani

Antibodies comprise the most versatile class of binding molecules, with numerous applications in biomedicine. Computational design of antibodies involves generating novel and diverse sequences, while maintaining structural consistency.…

Biomolecules · Quantitative Biology 2023-06-21 Igor Melnyk , Vijil Chenthamarakshan , Pin-Yu Chen , Payel Das , Amit Dhurandhar , Inkit Padhi , Devleena Das

This article presents a framework for generating optimisation models using a pre-trained generative transformer. The framework involves specifying the features that the optimisation model should have and using a language model to generate…

Neural and Evolutionary Computing · Computer Science 2023-05-11 Boris Almonacid

Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

Computation and Language · Computer Science 2025-11-25 Yanjun Lyu , Zihao Wu , Lu Zhang , Jing Zhang , Yiwei Li , Wei Ruan , Zhengliang Liu , Zeyu Zhang , Xiang Li , Rongjie Liu , Chao Huang , Wentao Li , Tianming Liu , Dajiang Zhu

Designing controllers for complex industrial electronic systems is challenging due to nonlinearities and parameter uncertainties, and traditional methods are often slow and costly. To address this, we propose a novel autonomous design…

Systems and Control · Electrical Eng. & Systems 2025-07-23 Chenggang Cui , Jiaming Liu , Peifeng Hui , Pengfeng Lin , Chuanlin Zhang

The increasing prevalence of Large Language Models (LMs) in critical applications highlights the need for controlled language generation strategies that are not only computationally efficient but that also enjoy performance guarantees. To…

Computation and Language · Computer Science 2026-03-16 Emily Cheng , Carmen Amo Alonso