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The training of molecular models of quantum mechanical properties based on statistical machine learning requires large datasets which exemplify the map from chemical structure to molecular property. Intelligent a priori selection of…

Gibbs sampling from continuous real-valued functions is a challenging problem of interest in machine learning. Here we leverage quantum Fourier transforms to build a quantum algorithm for this task when the function is periodic. We use the…

Quantum Physics · Physics 2024-07-23 Arsalan Motamedi , Pooya Ronagh

Causal graphs (CGs) are compact representations of the knowledge of the data generating processes behind the data distributions. When a CG is available, e.g., from the domain knowledge, we can infer the conditional independence (CI)…

Machine Learning · Computer Science 2021-08-18 Takeshi Teshima , Masashi Sugiyama

The Quantum Natural Gradient (QNG) method enhances optimization in variational quantum algorithms (VQAs) by incorporating geometric insights from the quantum state space through the Fubini-Study metric. In this work, we extend QNG by…

Quantum Physics · Physics 2025-05-06 Mourad Halla

Gaussian Process (GP) models are a powerful tool in probabilistic machine learning with a solid theoretical foundation. Thanks to current advances, modeling complex data with GPs is becoming increasingly feasible, which makes them an…

Machine Learning · Computer Science 2025-03-04 Sarem Seitz

Gaussian process (GP) emulator has been used as a surrogate model for predicting force field and molecular potential, to overcome the computational bottleneck of molecular dynamics simulation. Integrating both atomic force and energy in…

Chemical Physics · Physics 2022-05-13 Hao Li , Musen Zhou , Jessalyn Sebastian , Jianzhong Wu , Mengyang Gu

Mean-field molecular dynamics based on path integrals is used to approximate canonical quantum observables for particle systems consisting of nuclei and electrons. A computational bottleneck is the sampling from the Gibbs density of the…

Numerical Analysis · Mathematics 2023-11-30 Xin Huang , Petr Plechac , Mattias Sandberg , Anders Szepessy

Atomistic foundation models (AFMs) have great promise as accurate interatomic potentials, and have enabled data-efficient molecular dynamics simulations with near quantum mechanical accuracy. However, AFMs remain markedly slower at…

Materials Science · Physics 2025-09-29 Lingyu Kong , Jaeheon Shim , Guoxiang Hu , Victor Fung

We implement a quantum optimal control algorithm based on automatic differentiation and harness the acceleration afforded by graphics processing units (GPUs). Automatic differentiation allows us to specify advanced optimization criteria and…

Quantum Physics · Physics 2017-04-19 Nelson Leung , Mohamed Abdelhafez , Jens Koch , David I. Schuster

Affordances are fundamental descriptors of relationships between actions, objects and effects. They provide the means whereby a robot can predict effects, recognize actions, select objects and plan its behavior according to desired goals.…

Robotics · Computer Science 2024-02-12 Pedro Osório , Alexandre Bernardino , Ruben Martinez-Cantin , José Santos-Victor

The natural gradient method has been used effectively in conjugate Gaussian process models, but the non-conjugate case has been largely unexplored. We examine how natural gradients can be used in non-conjugate stochastic settings, together…

Machine Learning · Statistics 2018-03-28 Hugh Salimbeni , Stefanos Eleftheriadis , James Hensman

The natural gradient descent optimisation technique is an efficient optimising protocol for broad classes of classical and quantum systems that takes the underlying geometry of the parameter manifold into account by means of using either…

Quantum Physics · Physics 2026-04-08 Ankit Gill , Kunal Pal

The analytical gradient for periodic systems is presented, for the case of metallic systems. The total energy and the free energy are computed on the Hartree-Fock or density functional level, with the wave function being expanded in terms…

Materials Science · Physics 2012-04-25 K. Doll

Molecular discovery has brought great benefits to the chemical industry. Various molecule design techniques are developed to identify molecules with desirable properties. Traditional optimization methods, such as genetic algorithms,…

Biomolecules · Quantitative Biology 2025-11-05 Chris Zhuang , Debadyuti Mukherjee , Yingzhou Lu , Tianfan Fu , Ruqi Zhang

Training quantum neural networks (QNNs) using gradient-based or gradient-free classical optimisation approaches is severely impacted by the presence of barren plateaus in the cost landscapes. In this paper, we devise a framework for…

Quantum Physics · Physics 2024-06-04 Yidong Liao , Min-Hsiu Hsieh , Chris Ferrie

Current simulation of metal forging processes use advanced finite element methods. Such methods consist of solving mathematical equations, which takes a significant amount of time for the simulation to complete. Computational time can be…

Numerical Analysis · Mathematics 2023-03-20 Meduri Venkata Shivaditya , José Alves , Francesca Bugiotti , Frederic Magoules

Molecular Dynamics (MD) simulation is a powerful tool for understanding the dynamics and structure of matter. Since the resolution of MD is atomic-scale, achieving long time-scale simulations with femtosecond integration is very expensive.…

Machine Learning · Computer Science 2022-04-27 Zijie Li , Kazem Meidani , Prakarsh Yadav , Amir Barati Farimani

Combinatorial optimization is considered a promising class of problems in which quantum computers can show significant advantages. However, problems of practical relevance typically have more variables than current or foreseeable quantum…

Quantum Physics · Physics 2025-12-23 Mathias Schmid , Naeimeh Mohseni , Michael J. Hartmann

Image segmentation is the process of partitioning the image into significant regions easier to analyze. Nowadays, segmentation has become a necessity in many practical medical imaging methods as locating tumors and diseases. Hidden Markov…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 EL-Hachemi Guerrout , Samy Ait-Aoudia , Dominique Michelucci , Ramdane Mahiou

Hybrid quantum-classical algorithms provide ways to use noisy intermediate-scale quantum computers for practical applications. Expanding the portfolio of such techniques, we propose a quantum circuit learning algorithm that can be used to…