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Glioma is a prevalent brain tumor that poses a significant health risk to individuals. Accurate segmentation of brain tumor is essential for clinical diagnosis and treatment. The Segment Anything Model(SAM), released by Meta AI, is a…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Peng Zhang , Yaping Wang

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

Medical imaging plays a critical role in the diagnosis and treatment planning of various medical conditions, with radiology and pathology heavily reliant on precise image segmentation. The Segment Anything Model (SAM) has emerged as a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Amin Ranem , Niklas Babendererde , Moritz Fuchs , Anirban Mukhopadhyay

Since the release of Segment Anything 2 (SAM2), the medical imaging community has been actively evaluating its performance for 3D medical image segmentation. However, different studies have employed varying evaluation pipelines, resulting…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Yufan He , Pengfei Guo , Yucheng Tang , Andriy Myronenko , Vishwesh Nath , Ziyue Xu , Dong Yang , Can Zhao , Daguang Xu , Wenqi Li

Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Segment anything model (SAM) addresses two practical yet challenging segmentation tasks: \textbf{segment anything (SegAny)}, which utilizes a certain point to predict the mask for a single object of interest, and \textbf{segment everything…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Chaoning Zhang , Dongshen Han , Sheng Zheng , Jinwoo Choi , Tae-Ho Kim , Choong Seon Hong

Foundation segmentation models such as SAM and SAM-2 perform well on natural images but struggle with brain MRIs where structures like the caudate and thalamus lack sharp boundaries and have low contrast. Rather than fine tune these models…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Keith Moore

The Segment Anything Model (SAM) has revolutionized image segmentation through its innovative prompt-based approach, yet the critical role of prompt engineering in its success remains underexplored. This paper presents the first…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Yidong Jiang

The Segment Anything Model (SAM) is widely used for segmenting a diverse range of objects in natural images from simple user prompts like points or bounding boxes. However, SAM's performance decreases substantially when applied to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Tristan Piater , Björn Barz , Alexander Freytag

Liver cancer has a high incidence rate, but primary healthcare settings often lack experienced doctors. Advances in large models and AI technologies offer potential assistance. This work aims to address limitations in liver cancer diagnosis…

Medical Physics · Physics 2024-06-27 Xuzhou Wu , Guangxin Li , Xing Wang , Zeyu Xu , Yingni Wang , Jianming Xian , Xueyu Wang , Gong Li , Kehong Yuan

Volumetric segmentation is important in medical imaging, but current methods face challenges like requiring lots of manual annotations and being tailored to specific tasks, which limits their versatility. General segmentation models used…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Zifan Chen , Xinyu Nan , Jiazheng Li , Jie Zhao , Haifeng Li , Ziling Lin , Haoshen Li , Heyun Chen , Yiting Liu , Lei Tang , Li Zhang , Bin Dong

While the Segment Anything Model (SAM) has achieved remarkable success in image segmentation, its direct application to medical imaging remains hindered by fundamental challenges, including ambiguous boundaries, insufficient modeling of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yu Li , Da Chang , Xi Xiao

Melanoma segmentation in Whole Slide Images (WSIs) is useful for prognosis and the measurement of crucial prognostic factors such as Breslow depth and primary invasive tumor size. In this paper, we present a novel approach that uses the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Qingyuan Liu , Avideh Zakhor

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel

Lack of large expert annotated MR datasets makes training deep learning models difficult. Therefore, a cross-modality (MR-CT) deep learning segmentation approach that augments training data using pseudo MR images produced by transforming…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Jue Jiang , Yu-Chi Hu , Neelam Tyagi , Pengpeng Zhang , Andreas Rimner , Joseph O. Deasy , Harini Veeraraghavan

Online adaptive radiotherapy (ART) requires accurate and efficient auto-segmentation of target volumes and organs-at-risk (OARs) in mostly cone-beam computed tomography (CBCT) images. Propagating expert-drawn contours from the pre-treatment…

Computer Vision and Pattern Recognition · Computer Science 2023-05-10 Xiao Liang , Jaehee Chun , Howard Morgan , Ti Bai , Dan Nguyen , Justin C. Park , Steve Jiang

Accurate tumor segmentation is crucial for cancer diagnosis and treatment. While foundation models have advanced general-purpose segmentation, existing methods still struggle with: (1) limited incorporation of medical priors, (2) imbalance…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Runqi Meng , Sifan Song , Pengfei Jin , Yujin Oh , Lin Teng , Yulin Wang , Yiqun Sun , Ling Chen , Xiang Li , Quanzheng Li , Ning Guo , Dinggang Shen

Accurate lumbar spine segmentation is crucial for diagnosing spinal disorders. Existing methods typically use coarse-grained segmentation strategies that lack the fine detail needed for precise diagnosis. Additionally, their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Sheng Lian , Jianlong Cai , Dengfeng Pan , Guang-Yong Chen , Hao Xu , Fan Zhang , Guodong Fan , Shuo Li

The Segment Anything Model (SAM) represents a significant breakthrough into foundation models for computer vision, providing a large-scale image segmentation model. However, despite SAM's zero-shot performance, its segmentation masks lack…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Xianjie Liu , Keren Fu , Yao Jiang , Qijun Zhao

Background: The segment-anything model (SAM), introduced in April 2023, shows promise as a benchmark model and a universal solution to segment various natural images. It comes without previously-required re-training or fine-tuning specific…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Sheng He , Rina Bao , Jingpeng Li , Jeffrey Stout , Atle Bjornerud , P. Ellen Grant , Yangming Ou