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Quenched or frozen-in structural disorder is ubiquitous in real experimental systems. Much of the progress is achieved in understanding the phase separation of such systems using the diffusion-driven coarsening in Ising model with quenched…

Soft Condensed Matter · Physics 2023-08-15 Rounak Bhattacharyya , Bhaskar Sen Gupta

When cells measure concentrations of chemical signals, they may average multiple measurements over time in order to reduce noise in their measurements. However, when cells are in a environment that changes over time, past measurements may…

Cell Behavior · Quantitative Biology 2025-03-05 Aparajita Kashyap , Wei Wang , Brian A. Camley

We extend the continuum theories of active nematohydrodynamics to model a two-fluid mixture with separate velocity fields for each fluid component, coupled through a viscous drag. The model is used to study an active nematic fluid, mixed…

Soft Condensed Matter · Physics 2023-08-02 Saraswat Bhattacharyya , Julia M. Yeomans

Spatial gradients of diffusible signalling molecules play crucial roles in controlling diverse cellular behaviour such as cell differentiation, tissue patterning and chemotaxis. In this paper, we report the design and testing of a…

Quantitative Methods · Quantitative Biology 2016-12-15 Yasushi Saka , Murray MacPherson , Claudiu V. Giuraniuc

The temporal behaviour of segmentation clock oscillations show phase synchrony via mean field like coupling of delta protein restricting to nearest neighbours only, in a configuration of cells arranged in a regular three dimensional array.…

We investigate the emergence of sustained spatio-temporal behaviors in reaction-phase separation systems. We focus on binary systems, in which either one or both species can phase separate, and we discuss the stability of the homogeneous…

Pattern Formation and Solitons · Physics 2024-08-08 Dino Osmanovic , Elisa Franco

Deposition of smaller granular particles on a larger nucleus particle has been simulated in two-dimension using molecular dynamics method. Variation of sequences of velocity of deposited particles is conducted and reported in this work. The…

Soft Condensed Matter · Physics 2011-12-16 Euis Sustini , Siti Nurul Khotimah , Ferry Iskandar , Sparisoma Viridi

Cells continuously probe their environment with membrane receptors, achieving subsecond adaptation of their behaviour [1-3]. Recently, several receptors, including cadherins, were found to bind ligands with a lifetime of order of one…

Cell Behavior · Quantitative Biology 2007-09-26 Anne Pierres , Anil Prakasam , Dominique Touchard , Anne-Marie Benoliel , Pierre Bongrand , Deborah Leckband

Knowledge of bubble and drop size distributions in two-phase flows is important for characterizing a wide range of phenomena, including combustor ignition, sonar communication, and cloud formation. The physical mechanisms driving the…

Fluid Dynamics · Physics 2021-01-28 Wai Hong Ronald Chan , Michael S. Dodd , Perry L. Johnson , Parviz Moin

This work unravels the atomic details of the interaction of solute atoms with nanoscale crystalline defects. The complexity of this phenomenon is elucidated through detailed atom probe tomographic investigations on epitaxially-strained,…

Materials Science · Physics 2021-12-22 Samik Mukherjee , Simone Assali , Oussama Moutanabbir

Sampling the phase space of molecular systems -- and, more generally, of complex systems effectively modeled by stochastic differential equations -- is a crucial modeling step in many fields, from protein folding to materials discovery.…

Machine Learning · Computer Science 2023-12-12 Ellis R. Crabtree , Juan M. Bello-Rivas , Andrew L. Ferguson , Ioannis G. Kevrekidis

In a companion paper, we put forth a thermodynamic model for complex formation via a chemical reaction involving multiple macromolecular species, which may subsequently undergo liquid-liquid phase separation and a further transition into a…

Biological Physics · Physics 2024-07-26 Ruoyao Zhang , Sheng Mao , Mikko P. Haataja

We separate double stranded lambda phage DNA by applying a fixed force at a constant temperature ranging from 15C to 50C, and measure the minimum force required to separate the two strands, providing the first experimental determination of…

Soft Condensed Matter · Physics 2009-11-10 C. Danilowicz , Y. Kafri , R. S. Conroy , V. W. Coljee , J. Weeks , M. Prentiss

Using the formalism of rigorous statistical mechanics, we study the phenomena of phase separation and freezing-point depression upon freezing of solutions. Specifically, we devise an Ising-based model of a solvent-solute system and show…

Mathematical Physics · Physics 2007-05-23 Kenneth Alexander , Marek Biskup , Lincoln Chayes

We carried out three-dimensional simulations, with about 1.4 million particles, of phase segregation in a low density binary fluid mixture, described mesoscopically by energy and momentum conserving Boltzmann-Vlasov equations. Using a…

patt-sol · Physics 2008-02-03 S. Bastea , J. L. Lebowitz

In active systems, whose constituents have non-equilibrium dynamics at local level, fluid-fluid phase separation is widely observed. Examples include the formation of membraneless organelles within cells; the clustering of self-propelled…

Soft Condensed Matter · Physics 2025-07-11 M. E. Cates , C. Nardini

Phase-separated biomolecular condensates exhibit a wide range of dynamical properties, which depend on the sequences of the constituent proteins and RNAs. However, it is unclear to what extent condensate dynamics can be tuned without also…

Biomolecules · Quantitative Biology 2024-07-31 Yaxin An , Michael A. Webb , William M. Jacobs

The cellular automaton model is used to simulate diffusion and aggregation with dissociation of point particles in 2D. A continuous phase transition is found that separates creation of compact aggregates and fractal ones. The transition is…

Computational Physics · Physics 2015-04-17 Yuriy G. Gordienko , Elena E. Zasimchuk

In the absence of losses the phase of a Bose-Einstein condensate undergoes collapses and revivals in time due to elastic atomic interactions. As experiments necessarily involve inelastic collisions, we develop a model to describe the phase…

Atomic Physics · Physics 2009-10-31 Alice Sinatra , Yvan Castin

How do phase separated cellular structures set their size? To elucidate this, we study the dynamics and steady states of a phase separating nucleator that is advected by the self-straining cytoskeletal network which it nucleates. We find…

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