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As large language models (LLMs) increasingly mediate emotionally sensitive conversations, especially in mental health contexts, their ability to recognize and respond to high-risk situations becomes a matter of public safety. This study…

Artificial Intelligence (AI) chatbots leveraging Large Language Models (LLMs) are gaining traction in healthcare for their potential to automate patient interactions and aid clinical decision-making. This study examines the reliability of…

Artificial Intelligence · Computer Science 2024-05-24 Ayesha Siddika Nipu , K M Sajjadul Islam , Praveen Madiraju

People experiencing severe distress increasingly use Large Language Model (LLM) chatbots as mental health support tools. Discussions on social media have described how engagements were lifesaving for some, but evidence suggests that…

Human-Computer Interaction · Computer Science 2025-05-12 Inhwa Song , Sachin R. Pendse , Neha Kumar , Munmun De Choudhury

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

While Large Language Models (LLMs) are rapidly integrating into daily life, research on their risks often remains lab-based and disconnected from the problems users encounter "in the wild." While recent HCI research has begun to explore…

Computers and Society · Computer Science 2025-09-12 Lingyao Li , Renkai Ma , Zhaoqian Xue , Junjie Xiong

Individuals are increasingly relying on large language model (LLM)-enabled conversational agents for emotional support. While prior research has examined privacy and security issues in chatbots specifically designed for mental health…

Computers and Society · Computer Science 2025-07-16 Jabari Kwesi , Jiaxun Cao , Riya Manchanda , Pardis Emami-Naeini

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

The integration of Large Language Models (LLMs) into healthcare settings has gained significant attention, particularly for question-answering tasks. Given the high-stakes nature of healthcare, it is essential to ensure that LLM-generated…

Background: Clinical guidelines are central to safe evidence-based medicine in modern healthcare, providing diagnostic criteria, treatment options and monitoring advice for a wide range of illnesses. LLM-empowered chatbots have shown great…

Computation and Language · Computer Science 2025-05-07 Julia Ive , Felix Jozsa , Nick Jackson , Paulina Bondaronek , Ciaran Scott Hill , Richard Dobson

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

People increasingly seek personal advice from large language models (LLMs), yet whether humans follow their advice, and its consequences for their well-being, remains unknown. In a longitudinal randomised controlled trial with a…

Many people suffer from mental health problems but not everyone seeks professional help or has access to mental health care. AI chatbots have increasingly become a go-to for individuals who either have mental disorders or simply want…

Other Quantitative Biology · Quantitative Biology 2025-11-03 Aditya Naik , Jovi Thomas , Teja Sree Mandava , Himavanth Reddy Vemula

We investigate the role of large language models (LLMs) in supporting mental health by analyzing Reddit posts and comments about mental health conversations with ChatGPT. Our findings reveal that users value ChatGPT as a safe,…

Human-Computer Interaction · Computer Science 2025-10-28 Kyuha Jung , Gyuho Lee , Yuanhui Huang , Yunan Chen

This paper presents ChatCounselor, a large language model (LLM) solution designed to provide mental health support. Unlike generic chatbots, ChatCounselor is distinguished by its foundation in real conversations between consulting clients…

Computation and Language · Computer Science 2023-09-28 June M. Liu , Donghao Li , He Cao , Tianhe Ren , Zeyi Liao , Jiamin Wu

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

Background: As large language models (LLMs) are increasingly used in healthcare and medical consultation settings, a growing concern is whether these models can respond to medical inquiries in a manner that is ethically…

Computers and Society · Computer Science 2026-02-02 Hanhui Xu , Jiacheng Ji , Haoan Jin , Han Ying , Mengyue Wu

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi

We investigate and observe the behaviour and performance of Large Language Model (LLM)-backed chatbots in addressing misinformed prompts and questions with demographic information within the domains of Climate Change and Mental Health.…

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large language models (LLMs) chatbots like ChatGPT are increasingly used for mental health support. They offer accessible, therapeutic support but also raise concerns about misinformation, over-reliance, and risks in high-stakes contexts of…

Computers and Society · Computer Science 2025-12-09 Lingyao Li , Xiaoshan Huang , Renkai Ma , Ben Zefeng Zhang , Haolun Wu , Fan Yang , Chen Chen
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