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In preoperative imaging, the demarcation of rectal cancer with magnetic resonance images provides an important basis for cancer staging and treatment planning. Recently, deep learning has greatly improved the state-of-the-art method in…
Gliomas are the most common malignant brain tumors in adults and are among the most lethal. Despite aggressive treatment, the median survival rate is less than 15 months. Accurate multiparametric MRI (mpMRI) tumor segmentation is critical…
Inverse problems, such as accelerated MRI reconstruction, are ill-posed and an infinite amount of possible and plausible solutions exist. This may not only lead to uncertainty in the reconstructed image but also in downstream tasks such as…
Automatic segmentation of organs-at-risk (OARs) in CT scans using convolutional neural networks (CNNs) is being introduced into the radiotherapy workflow. However, these segmentations still require manual editing and approval by clinicians…
State-of-the-art brain tumor segmentation is based on deep learning models applied to multi-modal MRIs. Currently, these models are trained on images after a preprocessing stage that involves registration, interpolation, brain extraction…
Pancreatic cancer remains one of the leading causes of cancer-related mortality worldwide. Precise segmentation of pancreatic tumors from medical images is a bottleneck for effective clinical decision-making. However, achieving a high…
Despite the recent success of deep learning methods at achieving new state-of-the-art accuracy for medical image segmentation, some major limitations are still restricting their deployment into clinics. One major limitation of deep…
The segmentation of diseases is a popular topic explored by researchers in the field of machine learning. Brain tumors are extremely dangerous and require the utmost precision to segment for a successful surgery. Patients with tumors…
The interpretation of prostate MRI suffers from low agreement across radiologists due to the subtle differences between cancer and normal tissue. Image registration addresses this issue by accurately mapping the ground-truth cancer labels…
Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…
Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…
Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…
This paper proposes a two-stage segmentation model, variable-input based uncertainty measures and an uncertainty-guided post-processing method for prostate segmentation on 3D magnetic resonance images (MRI). The two-stage model was based on…
Semantic segmentation of medical images is an essential first step in computer-aided diagnosis systems for many applications. However, given many disparate imaging modalities and inherent variations in the patient data, it is difficult to…
In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…
Whole-body PET/CT scan is an important tool for diagnosing various malignancies (e.g., malignant melanoma, lymphoma, or lung cancer), and accurate segmentation of tumors is a key part for subsequent treatment. In recent years, CNN-based…
MR imaging is a valuable diagnostic tool allowing to non-invasively visualize patient anatomy and pathology with high soft-tissue contrast. However, MRI acquisition is typically time-consuming, leading to patient discomfort and increased…
Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…
Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…
This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…