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Quantum Annealing (QA) uses quantum fluctuations to search for a global minimum of an optimization-type problem faster than classical computers. To meet the demand for future internet traffic and mitigate the spectrum scarcity, this work…

Information Theory · Computer Science 2023-01-11 Eldar Gabdulsattarov , Khaled Rabie , Xingwang Li , Galymzhan Nauryzbayev

Conformational dynamics is crucial for ribonucleic acid (RNA) function. Techniques such as nuclear magnetic resonance, cryo-electron microscopy, small- and wide-angle X-ray scattering, chemical probing, single-molecule F\"orster resonance…

Biomolecules · Quantitative Biology 2025-01-31 Mattia Bernetti , Giovanni Bussi

Questions in computational molecular biology generate various discrete optimization problems, such as DNA sequence alignment and RNA secondary structure prediction. However, the optimal solutions are fundamentally dependent on the…

As quantum computing hardware rapidly advances, objectively evaluating the capabilities and error rates of new processors remains a critical challenge for the field. A clear and realistic understanding of current quantum performance is…

Quantum Physics · Physics 2026-04-21 Nitay Mayo , Tal Mor , Yossi Weinstein

The principle of Maximal Coding Rate Reduction (MCR$^2$) has recently been proposed as a training objective for learning discriminative low-dimensional structures intrinsic to high-dimensional data to allow for more robust training than…

Machine Learning · Computer Science 2022-04-04 Christina Baek , Ziyang Wu , Kwan Ho Ryan Chan , Tianjiao Ding , Yi Ma , Benjamin D. Haeffele

Machine learning algorithms, both in their classical and quantum versions, heavily rely on optimization algorithms based on gradients, such as gradient descent and alike. The overall performance is dependent on the appearance of local…

Quantum Physics · Physics 2024-04-26 Pablo Bermejo , Borja Aizpurua , Roman Orus

Quantum Machine Learning (QML) has seen significant advancements, driven by recent improvements in Noisy Intermediate-Scale Quantum (NISQ) devices. Leveraging quantum principles such as entanglement and superposition, quantum convolutional…

Contextual combinatorial optimization (CCO) plays a critical role in decision-making under uncertainty, yet remains a significant challenge. We present Quantum End-to-End Learning (QEL), the first quantum computing-based end-to-end learning…

Quantum Physics · Physics 2026-05-21 Jaehwan Lee , Changhyun Kwon

Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deliver a highly conformal dose to the tumor while sparing…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution. Quantum computation is a new computational paradigm which exploits quantum resources to speed up information processing tasks. Therefore, it is…

Quantum Physics · Physics 2023-02-20 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

A novel simulation strategy is proposed to search for semiconductor quantum devices which are optimized with respect to required performances. Based on evolutionary programming, a tecnique implementing the paradigm of genetic algorithms to…

Materials Science · Physics 2009-10-31 Guido Goldoni , Fausto Rossi

Scaling the size of monolithic quantum computer systems is a difficult task. As the number of qubits within a device increases, a number of factors contribute to decreases in yield and performance. To meet this challenge, distributed…

Quantum algorithms are emerging tools in the design of functional materials due to their powerful solution space search capability. How to balance the high price of quantum computing resources and the growing computing needs has become an…

Quantum Physics · Physics 2024-05-13 Zhihao Xu , Wenjie Shang , Seongmin Kim , Alexandria Bobbitt , Eungkyu Lee , Tengfei Luo

Among the genetic algorithms generally used for optimization problems in the recent decades, quantum-inspired variants are known for fast and high-fitness convergence and small resource requirement. Here the application to the patient…

Neural and Evolutionary Computing · Computer Science 2025-06-06 Akira SaiToh , Arezoo Modiri , Amit Sawant , Robabeh Rahimi

In the last few years, quantum computing and machine learning fostered rapid developments in their respective areas of application, introducing new perspectives on how information processing systems can be realized and programmed. The…

With conventional silicon-based computing approaching its physical and efficiency limits, biocomputing emerges as a promising alternative. This approach utilises biomaterials such as DNA and neurons as an interesting alternative to data…

Emerging Technologies · Computer Science 2024-08-15 Giulio Basso , Reinhold Scherer , Michael Taynnan Barros

A proposal for a magnetic quantum processor that consists of individual molecular spins coupled to superconducting coplanar resonators and transmission lines is carefully examined. We derive a simple magnetic quantum electrodynamics…

Materials Science · Physics 2016-11-02 M. D. Jenkins , D. Zueco , O. Roubeau , G. Aromí , J. Majer , F. Luis

In biology, predicting RNA secondary structures plays a vital role in determining its physical and chemical properties. Although we have powerful energy models to predict them as well as parametric analysis to understand the models…

Biomolecules · Quantitative Biology 2023-05-01 Doan Dai Nguyen

The evolution of the genome has led to very sophisticated and complex regulation. Because of the abundance of non-coding RNA (ncRNA) in the cell, different species will promiscuously associate with each other, suggesting collective dynamics…

Molecular Networks · Quantitative Biology 2018-05-16 J. M. Deutsch

In this paper we show that chordal structure can be used to devise efficient optimization methods for robust model predictive control problems. The chordal structure is used both for computing search directions efficiently as well as for…

Optimization and Control · Mathematics 2018-03-21 Anders Hansson , Sina Khoshfetrat Pakazad