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Semantic segmentation is essential in computer vision for various applications, yet traditional approaches face significant challenges, including the high cost of annotation and extensive training for supervised learning. Additionally, due…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yasufumi Kawano , Yoshimitsu Aoki

Nowadays, denoising diffusion probabilistic models have been adapted for many image segmentation tasks. However, existing end-to-end models have already demonstrated remarkable capabilities. Rather than using denoising diffusion…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Shi Zhenning , Dong Changsheng , Xie Xueshuo , Pan Bin , He Along , Li Tao

Building Virtual Cells that can accurately simulate cellular responses to perturbations is a long-standing goal in systems biology. A fundamental challenge is that high-throughput single-cell sequencing is destructive: the same cell cannot…

Machine Learning · Computer Science 2026-02-24 Xinyu Yuan , Xixian Liu , Ya Shi Zhang , Zuobai Zhang , Hongyu Guo , Jian Tang

Unsupervised segmentation of pulmonary pathologies in CT remains an open challenge due to the absence of annotated multi pathology cohorts and the failure of existing diffusion-based methods to exploit the quantitative Hounsfield Unit (HU)…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Catalin Fetita

Despite the recent visually-pleasing results achieved, the massive computational cost has been a long-standing flaw for diffusion probabilistic models (DPMs), which, in turn, greatly limits their applications on resource-limited platforms.…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Xingyi Yang , Daquan Zhou , Jiashi Feng , Xinchao Wang

In the realm of high-resolution (HR), fine-grained image segmentation, the primary challenge is balancing broad contextual awareness with the precision required for detailed object delineation, capturing intricate details and the finest…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Qian Yu , Peng-Tao Jiang , Hao Zhang , Jinwei Chen , Bo Li , Lihe Zhang , Huchuan Lu

Diffusion Models (DMs) have achieved great success in image generation and other fields. By fine sampling through the trajectory defined by the SDE/ODE solver based on a well-trained score model, DMs can generate remarkable high-quality…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Bowen Zheng , Tianming Yang

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

Interpreting EEG signals linked to spoken language presents a complex challenge, given the data's intricate temporal and spatial attributes, as well as the various noise factors. Denoising diffusion probabilistic models (DDPMs), which have…

Computation and Language · Computer Science 2023-11-15 Soowon Kim , Seo-Hyun Lee , Young-Eun Lee , Ji-Won Lee , Ji-Ha Park , Seong-Whan Lee

Denoising Diffusion Probabilistic Models (DDPMs) have emerged as a powerful family of generative models that can yield high-fidelity samples and competitive log-likelihoods across a range of domains, including image and speech synthesis.…

Machine Learning · Computer Science 2021-06-08 Daniel Watson , Jonathan Ho , Mohammad Norouzi , William Chan

Diffusion and flow-based models have enabled significant progress in generation tasks across various modalities and have recently found applications in predictive learning. However, unlike typical generation tasks that encourage sample…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yu Zhang , Xingzhuo Guo , Haoran Xu , Jialong Wu , Mingsheng Long

Diverse human motion prediction (HMP) aims to predict multiple plausible future motions given an observed human motion sequence. It is a challenging task due to the diversity of potential human motions while ensuring an accurate description…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Hua Yu , Yaqing Hou , Wenbin Pei , Qiang Zhang

Predicting stress fields in hyperelastic materials with complex microstructures remains challenging for traditional deep learning surrogates, which struggle to capture both sharp stress concentrations and the wide dynamic range of stress…

Machine Learning · Statistics 2026-03-20 Purna Vindhya Kota , Meer Mehran Rashid , Somdatta Goswami , Lori Graham-Brady

The Drift-Diffusion Model (DDM) is widely used in neuropsychological studies to understand the decision process by incorporating both reaction times and subjects' responses. Various models have been developed to estimate DDM parameters,…

Applications · Statistics 2025-07-03 Zekai Jin , Yaakov Stern , Seonjoo Lee

Diffusion models have emerged as a leading technique for generating images due to their ability to create high-resolution and realistic images. Despite their strong performance, diffusion models still struggle in managing image collections…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Hailong Yang , Te Zhang , Kup-sze Choi , Zhaohong Deng

This paper introduces a novel unified representation of diffusion models for image generation and segmentation. Specifically, we use a colormap to represent entity-level masks, addressing the challenge of varying entity numbers while…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Lu Qi , Lehan Yang , Weidong Guo , Yu Xu , Bo Du , Varun Jampani , Ming-Hsuan Yang

Generative modeling has recently undergone remarkable advancements, primarily propelled by the transformative implications of Diffusion Probabilistic Models (DPMs). The impressive capability of these models, however, often entails…

Machine Learning · Computer Science 2023-10-03 Gongfan Fang , Xinyin Ma , Xinchao Wang

Incremental brain tumor segmentation is critical for models that must adapt to evolving clinical datasets without retraining on all prior data. However, catastrophic forgetting, where models lose previously acquired knowledge, remains a…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Sashank Makanaboyina

Diffusion Probabilistic Models (DPMs) have emerged as a powerful class of deep generative models, achieving remarkable performance in image synthesis tasks. However, these models face challenges in terms of widespread adoption due to their…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Kidist Amde Mekonnen , Nicola Dall'Asen , Paolo Rota

Diffusion probabilistic models (DPMs) have become the state-of-the-art in high-quality image generation. However, DPMs have an arbitrary noisy latent space with no interpretable or controllable semantics. Although there has been significant…

Machine Learning · Computer Science 2024-08-27 Aneesh Komanduri , Chen Zhao , Feng Chen , Xintao Wu