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In the brain, fine-scale correlations combine to produce macroscopic patterns of activity. However, as experiments record from larger and larger populations, we approach a fundamental bottleneck: the number of correlations one would like to…

Biological Physics · Physics 2024-02-02 Christopher W. Lynn , Qiwei Yu , Rich Pang , Stephanie E. Palmer , William Bialek

Biological networks display a variety of activity patterns reflecting a web of interactions that is complex both in space and time. Yet inference methods have mainly focused on reconstructing, from the network's activity, the spatial…

Neurons and Cognition · Quantitative Biology 2015-08-19 Cristiano Capone , Carla Filosa , Guido Gigante , Federico Ricci-Tersenghi , Paolo del Giudice

A network of propagating nonlinear oscillatory modes (waves) in the human brain is shown to generate collectively synchronized spiking activity (hypersynchronous spiking) when both amplitude and phase coupling between modes are taken into…

Biological Physics · Physics 2021-04-28 Vitaly L. Galinsky , Lawrence R. Frank

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

Quantification of neuronal correlations in neuron populations helps us to understand neural coding rules. Such quantification could also reveal how neurons encode information in normal and disease conditions like Alzheimer's and…

Neurons and Cognition · Quantitative Biology 2021-05-10 Sathish Ande , Srinivas Avasarala , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

Lateral connection is a fundamental feature of biological neural circuits, facilitating local information processing and adaptive learning. In this work, we integrate lateral connections with a substructure selection network to develop a…

Neural and Evolutionary Computing · Computer Science 2025-04-01 Linghao Feng , Dongcheng Zhao , Sicheng Shen , Yi Zeng

Processes of evidence accumulation can make driver models more realistic, by explaining how drivers adjust their actions based on perceptual inputs and decision boundaries. The absence of a standard modelling approach limits their adoption;…

Neural and Evolutionary Computing · Computer Science 2026-03-05 Alberto Morando

Neuroscientists have worked on the problem of estimating synaptic properties, such as connectivity and strength, from simultaneously recorded spike trains since the 1960s. Recent years have seen renewed interest in the problem, coinciding…

Neurons and Cognition · Quantitative Biology 2024-05-07 Zach Saccomano , Sam Mckenzie , Horacio Rotstein , Asohan Amarasingham

In general, the behavior of large and complex aggregates of elementary components can not be understood nor extrapolated from the properties of a few components. The brain is a good example of this type of networked systems where some…

Chaotic Dynamics · Physics 2012-08-02 Ricardo Lopez-Ruiz , Daniele Fournier-Prunaret

The brain can efficiently learn a wide range of tasks, motivating the search for biologically inspired learning rules for improving current artificial intelligence technology. Most biological models are composed of point neurons, and cannot…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

Recent remarkable advances in the experimental techniques have provided a background for inferring neuronal couplings from point process data that includes a great number of neurons. Here, we propose a systematic procedure for pre- and…

Disordered Systems and Neural Networks · Physics 2020-07-08 Yu Terada , Tomoyuki Obuchi , Takuya Isomura , Yoshiyuki Kabashima

Sequential activation of neurons is a common feature of network activity during a variety of behaviors, including working memory and decision making. Previous network models for sequences and memory emphasized specialized architectures in…

Neurons and Cognition · Quantitative Biology 2016-03-16 Kanaka Rajan , Christopher D Harvey , David W Tank

This paper deals with the problem of inferring the signals and parameters that cause neural activity to occur. The ultimate challenge being to unveil brain's connectivity, here we focus on a microscopic vision of the problem, where single…

Computation · Statistics 2015-11-13 Pau Closas , Antoni Guillamon

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

Neurons and Cognition · Quantitative Biology 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice

In the absence of inhibition, excitatory neuronal networks can alternate between bursts and interburst intervals (IBI), with heterogeneous length distributions. As this dynamic remains unclear, especially the durations of each epoch, we…

Neurons and Cognition · Quantitative Biology 2020-12-17 Lou Zonca , David Holcman

Brain network is an important tool for understanding the brain, offering insights for scientific research and clinical diagnosis. Existing models for brain networks typically primarily focus on brain regions or overlook the complexity of…

Neurons and Cognition · Quantitative Biology 2024-05-30 Haoyu Hu , Hongrun Zhang , Chao Li

Recent experimental studies of living neural networks reveal that their global activation induced by electrical stimulation can be explained using the concept of bootstrap percolation on a directed random network. The experiment consists in…

Probability · Mathematics 2015-05-14 Hamed Amini

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Criticality can be exactly demonstrated in certain models of brain activity, yet it remains challenging to identify in empirical data. We trained a fully connected deep neural network to learn the phases of an excitable model unfolding on…

Neurons and Cognition · Quantitative Biology 2022-06-13 Hernan Bocaccio , Enzo Tagliazucchi

Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman