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In recent years, large language models (LLMs) have demonstrated remarkable potential across various medical applications. Building on this foundation, multimodal large language models (MLLMs) integrate LLMs with visual models to process…

Computation and Language · Computer Science 2025-03-11 Xiaoyi Liang , Mouxiao Bian , Moxin Chen , Lihao Liu , Junjun He , Jie Xu , Lin Li

Fundus imaging such as CFP, OCT and UWF is crucial for the early detection of retinal anomalies and diseases. Fundus image understanding, due to its knowledge-intensive nature, poses a challenging vision-language task. An emerging approach…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Yuchuan Deng , Qijie Wei , Kaiheng Qian , Jiazhen Liu , Zijie Xin , Bangxiang Lan , Jingyu Liu , Jianfeng Dong , Xirong Li

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Multimodal Large Language Models (MLLMs) have shown significant potential in medical image analysis. However, their capabilities in interpreting fundus images, a critical skill for ophthalmology, remain under-evaluated. Existing benchmarks…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Qijie Wei , Kaiheng Qian , Xirong Li

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Weihao Gao , Zhuo Deng , Zhiyuan Niu , Fuju Rong , Chucheng Chen , Zheng Gong , Wenze Zhang , Daimin Xiao , Fang Li , Zhenjie Cao , Zhaoyi Ma , Wenbin Wei , Lan Ma

Multimodal large language models (MLLMs) have recently demonstrated remarkable reasoning abilities with reinforcement learning paradigm. Although several multimodal reasoning models have been explored in the medical domain, most of them…

Artificial Intelligence · Computer Science 2025-09-11 Ruiqi Wu , Yuang Yao , Tengfei Ma , Chenran Zhang , Na Su , Tao Zhou , Geng Chen , Wen Fan , Yi Zhou

The advancement of general medical Multimodal Large Language Models (MLLMs) has shown great potential for building conversational assistants to support clinical diagnosis. However, their adaptation to highly specialized domains such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Hao Wang , Xin Li , Yujian Xiong , Jiajun Cheng , Jingjing Wang , Xiaobing Yu , Haiyu Wu , Shao Tang , Zhipeng Wang , Langechuan Liu , Shan Lin , Oana Dumitrascu , Yalin Wang

Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Huan Zheng , Yucheng Zhou , Tianyi Yan , Dubing Chen , Hongbo Lu , Wenlong Liao , Tao He , Pai Peng , Jianbing Shen

Multi-modal Large Language Models (MLLMs) are increasingly prominent in the field of artificial intelligence. These models not only excel in traditional vision-language tasks but also demonstrate impressive performance in contemporary…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Xiaotian Han , Quanzeng You , Yongfei Liu , Wentao Chen , Huangjie Zheng , Khalil Mrini , Xudong Lin , Yiqi Wang , Bohan Zhai , Jianbo Yuan , Heng Wang , Hongxia Yang

In recent years, Multi-modal Large Language Models (MLLMs) have achieved strong performance in OCR-centric Visual Question Answering (VQA) tasks, illustrating their capability to process heterogeneous data and exhibit adaptability across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Chen Duan , Zhentao Guo , Pei Fu , Zining Wang , Kai Zhou , Pengfei Yan

Multimodal large language models (MLLMs) have shown promising reasoning abilities, yet evaluating their performance in specialized domains remains challenging. STEM reasoning is a particularly valuable testbed because it provides highly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Jing Jin , Hao Liu , Yan Bai , Yihang Lou , Zhenke Wang , Tianrun Yuan , Juntong Chen , Yongkang Zhu , Fanhu Zeng , Xuanyu Zhu , Tao Feng , Yige Xu

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Medical image classifiers detect gastrointestinal diseases well, but they do not explain their decisions. Large language models can generate clinical text, yet they struggle with visual reasoning and often produce unstable or incorrect…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Md. Najib Hasan , Imran Ahmad , Sourav Basak Shuvo , Md. Mahadi Hasan Ankon , Sunanda Das , Nazmul Siddique , Hui Wang

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

Computation and Language · Computer Science 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei

In this paper, we introduce ILLUME, a unified multimodal large language model (MLLM) that seamlessly integrates multimodal understanding and generation capabilities within a single large language model through a unified next-token…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chunwei Wang , Guansong Lu , Junwei Yang , Runhui Huang , Jianhua Han , Lu Hou , Wei Zhang , Hang Xu

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Multimodal Large Language Models (MLLMs) have made substantial progress in recent years. However, their rigorous evaluation within specialized domains like finance is hindered by the absence of datasets characterized by professional-level…

Artificial Intelligence · Computer Science 2025-11-25 Shuangyan Deng , Haizhou Peng , Jiachen Xu , Rui Mao , Ciprian Doru Giurcăneanu , Jiamou Liu

Multimodal Large Language Models (MLLMs) have achieved significant advances in integrating visual and linguistic information, yet their ability to reason about complex and real-world scenarios remains limited. The existing benchmarks are…

Multimodal large language models (MLLMs) have demonstrated powerful capabilities in general spatial understanding and reasoning. However, their fine-grained spatial understanding and reasoning capabilities in complex urban scenarios have…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Jun Zhang , Jie Feng , Long Chen , Junhui Wang , Zhicheng Liu , Depeng Jin , Yong Li
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