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Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Zhe Xu , Cheng Jin , Yihui Wang , Ziyi Liu , Hao Chen

Reasoning lies at the heart of intelligence, shaping the ability to make decisions, draw conclusions, and generalize across domains. In artificial intelligence, as systems increasingly operate in open, uncertain, and multimodal…

Multimodal Large Language Models (MLLMs) demonstrate remarkable capabilities but often struggle with complex, multi-step mathematical reasoning, where minor errors in visual perception or logical deduction can lead to complete failure.…

Computation and Language · Computer Science 2025-08-08 Jianghangfan Zhang , Yibo Yan , Kening Zheng , Xin Zou , Song Dai , Xuming Hu

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Large language models (LLMs) with billions of parameters exhibit in-context learning abilities, enabling few-shot learning on tasks that the model was not specifically trained for. Traditional models achieve breakthrough performance on…

Artificial Intelligence · Computer Science 2025-11-04 Aske Plaat , Annie Wong , Suzan Verberne , Joost Broekens , Niki van Stein , Thomas Back

Roadway safety and mobility remain critical challenges for modern transportation systems, demanding innovative analytical frameworks capable of addressing complex, dynamic, and heterogeneous environments. While traditional engineering…

Artificial Intelligence · Computer Science 2025-12-10 Muhammad Monjurul Karim , Yan Shi , Shucheng Zhang , Bingzhang Wang , Mehrdad Nasri , Yinhai Wang

While Multimodal Large Language Models (MLLMs) have achieved impressive progress in vision-language understanding, they still struggle with complex multi-step reasoning, often producing logically inconsistent or partially correct solutions.…

Artificial Intelligence · Computer Science 2025-06-06 Lingxiao Du , Fanqing Meng , Zongkai Liu , Zhixiang Zhou , Ping Luo , Qiaosheng Zhang , Wenqi Shao

Understanding the contents of multimodal documents is essential to accurately extract relevant evidence and use it for reasoning. Existing document understanding models tend to generate answers with a single word or phrase directly,…

Information Retrieval · Computer Science 2024-08-15 Jinxu Zhang

Significant advancements has recently been achieved in the field of multi-modal large language models (MLLMs), demonstrating their remarkable capabilities in understanding and reasoning across diverse tasks. However, these models are often…

Computation and Language · Computer Science 2024-08-06 Zhaowei Li , Wei Wang , YiQing Cai , Xu Qi , Pengyu Wang , Dong Zhang , Hang Song , Botian Jiang , Zhida Huang , Tao Wang

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Multimodal large language models (MLLMs) have emerged as a promising paradigm for dental image analysis. However, their ability to capture the multi-level cognitive processes required for radiographic analysis remains unclear. Here, we…

Computation and Language · Computer Science 2026-05-11 Rongyang Wang , Shuang Zhou , Jiashuo Wang , Wenya Xie , Xiaoxia Che

Recently, there has been a growing interest in Multimodal Large Language Models (MLLMs) due to their remarkable potential in various tasks integrating different modalities, such as image and text, as well as applications such as image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Jihen Amara , Birgitta König-Ries , Sheeba Samuel

Multimodal large language models (MLLMs) have recently demonstrated remarkable reasoning abilities with reinforcement learning paradigm. Although several multimodal reasoning models have been explored in the medical domain, most of them…

Artificial Intelligence · Computer Science 2025-09-11 Ruiqi Wu , Yuang Yao , Tengfei Ma , Chenran Zhang , Na Su , Tao Zhou , Geng Chen , Wen Fan , Yi Zhou

The reasoning capabilities of LLM (Large Language Model) are widely acknowledged in recent research, inspiring studies on tool learning and autonomous agents. LLM serves as the "brain" of the agent, orchestrating multiple tools for…

Machine Learning · Computer Science 2024-03-26 Xiangyan Liu , Rongxue Li , Wei Ji , Tao Lin

The emergence of vision-language models (VLMs) has opened new possibilities for clinical reasoning and has shown promising performance in dermatological diagnosis. However, their trustworthiness and clinical utility are often limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Zehao Liu , Wejieying Ren , Jipeng Zhang , Tianxiang Zhao , Jingxi Zhu , Xiaoting Li , Vasant G. Honavar

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

Computation and Language · Computer Science 2025-06-23 Xiaotian Zhang , Yuan Wang , Zhaopeng Feng , Ruizhe Chen , Zhijie Zhou , Yan Zhang , Hongxia Xu , Jian Wu , Zuozhu Liu

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen
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