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Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Yuci Liang , Xinheng Lyu , Wenting Chen , Meidan Ding , Jipeng Zhang , Xiangjian He , Song Wu , Xiaohan Xing , Sen Yang , Xiyue Wang , Linlin Shen

DeepSeek-R1 is a cutting-edge open-source large language model (LLM) developed by DeepSeek, showcasing advanced reasoning capabilities through a hybrid architecture that integrates mixture of experts (MoE), chain of thought (CoT) reasoning,…

Computation and Language · Computer Science 2025-06-03 Jiancheng Ye , Sophie Bronstein , Jiarui Hai , Malak Abu Hashish

Building on the success of text-based reasoning models like DeepSeek-R1, extending these capabilities to multimodal reasoning holds great promise. While recent works have attempted to adapt DeepSeek-R1-style reinforcement learning (RL)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Jie Yang , Feipeng Ma , Zitian Wang , Dacheng Yin , Kang Rong , Fengyun Rao , Ruimao Zhang

Reasoning language models (RLMs), also known as Large Reasoning Models (LRMs), such as OpenAI's o1 and o3, DeepSeek-R1, and Alibaba's QwQ, have redefined AI's problem-solving capabilities by extending LLMs with advanced reasoning…

Scientific reasoning, the process through which humans apply logic, evidence, and critical thinking to explore and interpret scientific phenomena, is essential in advancing knowledge reasoning across diverse fields. However, despite…

Computation and Language · Computer Science 2026-04-21 Yibo Yan , Shen Wang , Jiahao Huo , Jingheng Ye , Zhendong Chu , Xuming Hu , Philip S. Yu , Carla Gomes , Bart Selman , Qingsong Wen

Multimodal Large Language Models (MLLMs) have become a powerful tool for integrating visual and textual information. Despite their exceptional performance on visual understanding benchmarks, measuring their ability to reason abstractly…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Nilay Yilmaz , Maitreya Patel , Yiran Lawrence Luo , Tejas Gokhale , Chitta Baral , Suren Jayasuriya , Yezhou Yang

Reinforcement Learning (RL) has shown promise in improving the reasoning abilities of Large Language Models (LLMs). However, the specific challenges of adapting RL to multimodal data and formats remain relatively unexplored. In this work,…

Machine Learning · Computer Science 2025-05-20 Zirun Guo , Minjie Hong , Tao Jin

Multimodal large language models (MLLMs) that integrate visual and textual reasoning leverage chain-of-thought (CoT) prompting to tackle complex visual tasks, yet continue to exhibit visual hallucinations and an over-reliance on textual…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Jing Bi , Guangyu Sun , Ali Vosoughi , Chen Chen , Chenliang Xu

Large Language Models (LLMs) have achieved remarkable reliability and advanced capabilities through extended test-time reasoning. However, extending these capabilities to Multi-modal Large Language Models (MLLMs) remains a significant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yuhao Dong , Zuyan Liu , Shulin Tian , Yongming Rao , Ziwei Liu

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

Machine Learning · Computer Science 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Despite being widely used to support clinical care, general-purpose large multimodal models (LMMs) have generally shown poor or inconclusive performance in medical image interpretation, particularly in pathology, where gigapixel images are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Thomas A. Buckley , Kian R. Weihrauch , Katherine Latham , Andrew Z. Zhou , Padmini A. Manrai , Arjun K. Manrai

Multimodal Large Language Models (MLLMs) have demonstrated robust capabilities in recognizing everyday human activities, yet their potential for analyzing clinically significant involuntary movements in neurological disorders remains…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Lina Zhang , Tonmoy Monsoor , Mehmet Efe Lorasdagi , Prateik Sinha , Chong Han , Peizheng Li , Yuan Wang , Jessica Pasqua , Colin McCrimmon , Rajarshi Mazumder , Vwani Roychowdhury

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…

The ability to perform multi-modal multi-hop reasoning by iteratively integrating information across various modalities and external knowledge is critical for addressing complex real-world challenges. However, existing Multi-modal Large…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Tao Zhang , Ziqi Zhang , Zongyang Ma , Yuxin Chen , Bing Li , Chunfeng Yuan , Guangting Wang , Fengyun Rao , Ying Shan , Weiming Hu

Multimodal Large Language Models (MLLMs) have demonstrated remarkable effectiveness in various general-domain scenarios, such as visual question answering and image captioning. Recently, researchers have increasingly focused on empowering…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yan Shu , Chi Liu , Robin Chen , Derek Li , Bryan Dai

Vision-language models (VLMs) have achieved impressive progress in natural image reasoning, yet their potential in medical imaging remains underexplored. Medical vision-language tasks demand precise understanding and clinically coherent…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yuxiang Lai , Jike Zhong , Ming Li , Shitian Zhao , Yuheng Li , Konstantinos Psounis , Xiaofeng Yang

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…