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The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

Foundation models such as the recently introduced Segment Anything Model (SAM) have achieved remarkable results in image segmentation tasks. However, these models typically require user interaction through handcrafted prompts such as…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yihang Fu , Ziyang Chen , Yiwen Ye , Xingliang Lei , Zhisong Wang , Yong Xia

Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Xie , Hao Tang , Dawen Cai , Yan Yan , Gady Agam

Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Chengyin Li , Prashant Khanduri , Yao Qiang , Rafi Ibn Sultan , Indrin Chetty , Dongxiao Zhu

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel

End-to-end medical image segmentation is of great value for computer-aided diagnosis dominated by task-specific models, usually suffering from poor generalization. With recent breakthroughs brought by the segment anything model (SAM) for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Xian Lin , Yangyang Xiang , Li Yu , Zengqiang Yan

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

Deep learning-based medical image segmentation models often suffer from domain shift, where the models trained on a source domain do not generalize well to other unseen domains. As a prompt-driven foundation model with powerful…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Yifan Gao , Wei Xia , Dingdu Hu , Wenkui Wang , Xin Gao

Medical image segmentation often faces the challenge of prohibitively expensive annotation costs. While few-shot learning offers a promising solution to alleviate this burden, conventional approaches still rely heavily on pre-training with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Jie Xu , Xiaokang Li , Chengyu Yue , Yuanyuan Wang , Yi Guo

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Due to the flexibility of prompting, foundation models have become the dominant force in the domains of natural language processing and image generation. With the recent introduction of the Segment Anything Model (SAM), the prompt-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Yichi Zhang , Rushi Jiao

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

The recently introduced Segment Anything Model (SAM), a Visual Foundation Model (VFM), has demonstrated impressive capabilities in zero-shot segmentation tasks across diverse natural image datasets. Despite its success, SAM encounters…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Chunpeng Zhou , Kangjie Ning , Qianqian Shen , Sheng Zhou , Zhi Yu , Haishuai Wang

The Segment Anything Model (SAM) represents a state-of-the-art research advancement in natural image segmentation, achieving impressive results with input prompts such as points and bounding boxes. However, our evaluation and recent…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Junlong Cheng , Jin Ye , Zhongying Deng , Jianpin Chen , Tianbin Li , Haoyu Wang , Yanzhou Su , Ziyan Huang , Jilong Chen , Lei Jiang , Hui Sun , Junjun He , Shaoting Zhang , Min Zhu , Yu Qiao

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Domain Generalization (DG) aims to reduce domain shifts between domains to achieve promising performance on the unseen target domain, which has been widely practiced in medical image segmentation. Single-source domain generalization (SDG)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Hanhui Wang , Huaize Ye , Yi Xia , Xueyan Zhang
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