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Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

We present DiffInfinite, a hierarchical diffusion model that generates arbitrarily large histological images while preserving long-range correlation structural information. Our approach first generates synthetic segmentation masks,…

We introduce the Pyramid Diffusion Model (PDM), a novel architecture designed for ultra-high-resolution image synthesis. PDM utilizes a pyramid latent representation, providing a broader design space that enables more flexible, structured,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Jiajie Yang

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Solving medical imaging data scarcity through semantic image generation has attracted growing attention in recent years. However, existing generative models mainly focus on synthesizing whole-organ or large-tissue structures, showing…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jiahao Xia , Yutao Hu , Yaolei Qi , Zhenliang Li , Wenqi Shao , Junjun He , Ying Fu , Longjiang Zhang , Guanyu Yang

Recovering noise-covered details from low-light images is challenging, and the results given by previous methods leave room for improvement. Recent diffusion models show realistic and detailed image generation through a sequence of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Dewei Zhou , Zongxin Yang , Yi Yang

Diffusion models have demonstrated remarkable performance in image and video synthesis. However, scaling them to high-resolution inputs is challenging and requires restructuring the diffusion pipeline into multiple independent components,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ivan Skorokhodov , Willi Menapace , Aliaksandr Siarohin , Sergey Tulyakov

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

The performance of single image super-resolution depends heavily on how to generate and complement high-frequency details to low-resolution images. Recently, diffusion-based DDPM models exhibit great potential in generating high-quality…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Xingjian Wang , Li Chai , Jiming Chen

Medical image segmentation has been significantly advanced with the rapid development of deep learning (DL) techniques. Existing DL-based segmentation models are typically discriminative; i.e., they aim to learn a mapping from the input…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Tao Chen , Chenhui Wang , Zhihao Chen , Yiming Lei , Hongming Shan

Fairness is an important topic for medical image analysis, driven by the challenge of unbalanced training data among diverse target groups and the societal demand for equitable medical quality. In response to this issue, our research adopts…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Wenyi Li , Haoran Xu , Guiyu Zhang , Huan-ang Gao , Mingju Gao , Mengyu Wang , Hao Zhao

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Synthesizing high-quality images from low-field MRI holds significant potential. Low-field MRI is cheaper, more accessible, and safer, but suffers from low resolution and poor signal-to-noise ratio. This synthesis process can reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Zhenxuan Zhang , Peiyuan Jing , Zi Wang , Ula Briski , Coraline Beitone , Yue Yang , Yinzhe Wu , Fanwen Wang , Liutao Yang , Jiahao Huang , Zhifan Gao , Zhaolin Chen , Kh Tohidul Islam , Guang Yang , Peter J. Lally

The rapid progress in deep generative models has led to the creation of incredibly realistic synthetic images that are becoming increasingly difficult to distinguish from real-world data. The widespread use of Variational Models, Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Anant Mehta , Bryant McArthur , Nagarjuna Kolloju , Zhengzhong Tu

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Junyan Zhang , Mengxiao Geng , Pinhuang Tan , Yi Liu , Zhili Liu , Bin Huang , Qiegen Liu

Despite the success of generating high-quality images given any text prompts by diffusion-based generative models, prior works directly generate the entire images, but cannot provide object-wise manipulation capability. To support wider…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Runhui Huang , Kaixin Cai , Jianhua Han , Xiaodan Liang , Renjing Pei , Guansong Lu , Songcen Xu , Wei Zhang , Hang Xu

Recent advancements in diffusion models have greatly improved the quality and diversity of synthesized content. To harness the expressive power of diffusion models, researchers have explored various controllable mechanisms that allow users…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Tsai-Shien Chen , Chieh Hubert Lin , Hung-Yu Tseng , Tsung-Yi Lin , Ming-Hsuan Yang
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