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Reproducibility in research remains hindered by complex systems involving data, models, tools, and algorithms. Studies highlight a reproducibility crisis due to a lack of standardized reporting, code and data sharing, and rigorous…

Software Engineering · Computer Science 2024-11-05 Venkat S. Malladi , Maria Yazykova , Olesya Melnichenko , Yulia Dubinina

This special volume of Statistical Sciences presents some innovative, if not provocative, ideas in the area of reliability, or perhaps more appropriately named, integrated system assessment. In this age of exponential growth in science,…

Methodology · Statistics 2009-09-29 Sallie Keller-McNulty , Alyson Wilson , Christine Anderson-Cook

Infrastructure shapes societies and scientific discovery. Traditional scientific infrastructure, often static and fragmented, leads to issues like data silos, lack of interoperability and reproducibility, and unsustainable short-lived…

Neurons and Cognition · Quantitative Biology 2025-08-15 Satrajit S. Ghosh

Recently, there has been growing interest in using Large Language Models (LLMs) for scientific research. Numerous benchmarks have been proposed to evaluate the ability of LLMs for scientific research. However, current benchmarks are mostly…

Computation and Language · Computer Science 2024-11-08 Liangtai Sun , Yang Han , Zihan Zhao , Da Ma , Zhennan Shen , Baocai Chen , Lu Chen , Kai Yu

Large language models (LLMs) have demonstrated exceptional reasoning capabilities, and co-evolving paradigms have shown promising results in domains such as code and math. However, in scientific reasoning tasks, these models remain fragile…

Artificial Intelligence · Computer Science 2026-02-13 Xiaohan He , Shiyang Feng , Songtao Huang , Lei Bai , Bin Wang , Bo Zhang

Data science is an integrated workflow of technical, analytical, communication, and ethical skills, but current AI benchmarks focus mostly on constituent parts. We test whether AI models can generate end-to-end data science projects. To do…

Other Statistics · Statistics 2026-02-17 Evelyn Hughes , Rohan Alexander

Background: Sustainable software engineering (SSE) means creating software in a way that meets present needs without undermining our collective capacity to meet our future needs. It is typically conceptualized as several intersecting…

Software Engineering · Computer Science 2024-04-02 Sean McGuire , Erin Shultz , Bimpe Ayoola , Paul Ralph

Large language models (LLMs) are playing an increasingly important role in scientific research, yet there remains a lack of comprehensive benchmarks to evaluate the breadth and depth of scientific knowledge embedded in these models. To…

Computation and Language · Computer Science 2025-10-08 Kehua Feng , Xinyi Shen , Weijie Wang , Xiang Zhuang , Yuqi Tang , Qiang Zhang , Keyan Ding

Large language models (LLMs) have a transformative impact on a variety of scientific tasks across disciplines including biology, chemistry, medicine, and physics. However, ensuring the safety alignment of these models in scientific research…

Evaluation is the foundation of empirical science, yet the evaluation of evaluation itself -- so-called meta-evaluation -- remains strikingly underdeveloped. While methods such as observational studies, design of experiments (DoE), and…

Methodology · Statistics 2026-01-22 Hongxiao Li , Chenxi Wang , Fanda Fan , Zihan Wang , Wanling Gao , Lei Wang , Jianfeng Zhan

The landscape of science and technology is characterized by its dynamic and evolving nature, constantly reshaped by new discoveries, innovations, and paradigm shifts. Moreover, science is undergoing a remarkable shift towards increasing…

Information Retrieval · Computer Science 2025-12-22 Ashkan Ebadi , Alain Auger , Yvan Gauthier

Existing prompt-optimization techniques rely on local signals to update behavior, often neglecting broader and recurring patterns across tasks, leading to poor generalization; they further rely on full-prompt rewrites or unstructured…

Software Engineering · Computer Science 2026-03-24 Balaji Dinesh Gangireddi , Aniketh Garikaparthi , Manasi Patwardhan , Arman Cohan

Scientific fact-checking aims to determine the veracity of scientific claims by retrieving and analysing evidence from research literature. The problem is inherently more complex than general fact-checking since it must accommodate the…

Information Retrieval · Computer Science 2025-08-18 Xingyu Deng , Xi Wang , Mark Stevenson

This paper presents EASE (Effortless Algorithmic Solution Evolution), an open-source and fully modular framework for iterative algorithmic solution generation leveraging large language models (LLMs). EASE integrates generation, testing,…

Machine Learning · Computer Science 2025-09-24 Adam Viktorin , Tomas Kadavy , Jozef Kovac , Michal Pluhacek , Roman Senkerik

Artificial Intelligence for Science (AI4S) is an emerging research field that utilizes machine learning advancements to tackle complex scientific computational issues, aiming to enhance computational efficiency and accuracy. However, the…

Machine Learning · Computer Science 2023-11-30 Yatao Li , Jianfeng Zhan

In most prediction and estimation situations, scientists consider various statistical models for the same problem, and naturally want to select amongst the best. Hansen et al. (2011) provide a powerful solution to this problem by the…

Methodology · Statistics 2026-01-23 Sebastian Arnold , Georgios Gavrilopoulos , Benedikt Schulz , Johanna Ziegel

Learned representations of scientific documents can serve as valuable input features for downstream tasks without further fine-tuning. However, existing benchmarks for evaluating these representations fail to capture the diversity of…

Computation and Language · Computer Science 2023-11-14 Amanpreet Singh , Mike D'Arcy , Arman Cohan , Doug Downey , Sergey Feldman

We introduce the Axial Seamount Eruption Forecasting Experiment (EFE), a real-time initiative designed to test the predictability of volcanic eruptions through a transparent, physics-based framework. The experiment is inspired by the…

In the search for a sustainable approach for software ecosystems that supports experimental and observational science (EOS) across Oak Ridge National Laboratory (ORNL), we conducted a survey to understand the current and future landscape of…

Software Engineering · Computer Science 2022-09-07 David E Bernholdt , Mathieu Doucet , William F Godoy , Addi Malviya-Thakur , Gregory R Watson