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Multimodal large language models (MLLMs) have achieved significant success in the general field of image processing. Their emerging task generalization and freeform conversational capabilities can greatly facilitate medical diagnostic…
Microwell microfluidics has been utilized for single-cell analysis to reveal heterogeneity in gene expression, signaling pathways, and phenotypic responses for identifying rare cell types, understanding disease progression, and developing…
Medical image segmentation driven by free-text clinical instructions is a critical frontier in computer-aided diagnosis. However, existing multimodal and foundation models struggle with the semantic ambiguity of clinical reports and fail to…
This report relates to a study group hosted by the EPSRC funded network, Integrating data-driven BIOphysical models into REspiratory MEdicine (BIOREME), and supported by SofTMech and Innovate UK, Business Connect. This report summarises the…
Time series data from the Intensive Care Unit (ICU) provides critical information for patient monitoring. While recent advancements in applying Large Language Models (LLMs) to time series modeling (TSM) have shown great promise, their…
Large Language Models (LLMs) have the potential to revolutionize data analytics by simplifying tasks such as data discovery and SQL query synthesis through natural language interactions. This work serves as a pivotal first step toward the…
Large language models (LLMs) hold significant potential for mental health support, capable of generating empathetic responses and simulating therapeutic conversations. However, existing LLM-based approaches often lack the clinical grounding…
Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…
Recent advancements in Multimodal Large Language Models (MLLMs) have greatly improved their abilities in image understanding. However, these models often struggle with grasping pixel-level semantic details, e.g., the keypoints of an object.…
Acute stroke demands prompt diagnosis and treatment to achieve optimal patient outcomes. However, the intricate and irregular nature of clinical data associated with acute stroke, particularly blood pressure (BP) measurements, presents…
Time series anomaly detection (TSAD) plays a crucial role in various industries by identifying atypical patterns that deviate from standard trends, thereby maintaining system integrity and enabling prompt response measures. Traditional TSAD…
Power system time series analytics is critical in understanding the system operation conditions and predicting the future trends. Despite the wide adoption of Artificial Intelligence (AI) tools, many AI-based time series analytical models…
According to the World Health Organisation (WHO), 235 million people suffer from respiratory illnesses and four million people die annually due to air pollution. Regular lung health monitoring can lead to prognoses about deteriorating lung…
Large language models (LLMs) are rapidly being integrated into psychological research as research tools, evaluation targets, human simulators, and cognitive models. However, recent evidence reveals severe measurement unreliability:…
We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…
In recent years, pre-trained large language models (LLMs) have achieved tremendous success in the field of Natural Language Processing (NLP). Prior studies have primarily focused on general and generic domains, with relatively less research…
Respiratory diseases remain a leading cause of mortality worldwide, highlighting the need for faster and more accurate diagnostic tools. This work presents a novel approach leveraging digital stethoscope technology for automatic respiratory…
This study aims to simulate real-world clinical scenarios to systematically evaluate the ability of Large Language Models (LLMs) to extract core medical information from patient chief complaints laden with noise and redundancy, and to…
Automated molecular structure elucidation remains challenging, as existing approaches often depend on pre-compiled databases or restrict themselves to single spectroscopic modalities. Here we introduce SpectraLLM, a large language model…
Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…