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Network meta-analysis (NMA) is widely used in evidence synthesis to estimate the effects of several competing interventions for a given clinical condition. One of the challenges is that it is not possible in disconnected networks. Component…

Methodology · Statistics 2022-05-24 Maria Petropoulou , Gerta Rücker , Stephanie Weibel , Peter Kranke , Guido Schwarzer

Component network meta-analysis (CNMA) is a statistical methodology that enables estimation of relative effects for multi-component treatments, such as combinations of antidepressants, and individual components, such as single…

Methodology · Statistics 2026-05-15 Augustine Wigle , Audrey Béliveau , Adriani Nikolakopoulou , Lifeng Lin

Network meta-analysis (NMA) combines evidence from multiple trials to compare the effectiveness of a set of interventions. In public health research, interventions are often complex, made up of multiple components or features. This makes it…

Methodology · Statistics 2024-01-04 Annabel L Davies , Julian P T Higgins

Network meta-analysis (NMA) allow combining efficacy information from multiple comparisons from trials assessing different therapeutic interventions for a given disease and to estimate unobserved comparisons from a network of observed…

Methodology · Statistics 2016-04-08 Victoria Nyaga , Marc Aerts , Marc Arbyn

Network meta-analysis (NMA) is widely used to compare multiple interventions simultaneously by synthesizing direct and indirect evidence. The general fixed or random effects contrast-based NMA model can be applied to different outcomes and…

Methodology · Statistics 2026-03-03 Harlan Campbell , Jeroen P. Jansen

Network meta-analysis (NMA) is a technique used in medical statistics to combine evidence from multiple medical trials. NMA defines an inference and information processing problem on a network of treatment options and trials connecting the…

Statistical Mechanics · Physics 2022-11-30 Annabel L. Davies , Tobias Galla

Network meta-analysis (NMA) synthesizes evidence for multiple treatments, but decisions on node formation can have important statistical implications including bias or inflated uncertainty. Existing data-driven methods often lack…

Methodology · Statistics 2025-06-30 Timothy Disher , Chris Cameron , Brian Hutton

Network Meta-Analysis (NMA) is an increasingly popular evidence synthesis tool that can provide a ranking of competing treatments, also known as a treatment hierarchy. Treatment-Covariate Interactions (TCIs) can be included in NMA models to…

Methodology · Statistics 2026-05-13 Augustine Wigle , Erica E. M. Moodie

Network meta-analysis of diagnostic test accuracy (NMA-DTA) is a relatively new field, involving combining evidence across studies to evaluate and compare the accuracy of different tests for a given condition. However, the methods proposed…

Methodology · Statistics 2026-04-23 Efthymia Derezea , Gabriel Rogers , Nicky J Welton , Hayley E Jones

Bayesian Model Averaging (BMA) is an application of Bayesian inference to the problems of model selection, combined estimation and prediction that produces a straightforward model choice criteria and less risky predictions. However, the…

Methodology · Statistics 2017-11-08 Tiago M. Fragoso , Francisco Louzada Neto

Conformal prediction has emerged as a popular technique for facilitating valid predictive inference across a spectrum of machine learning models, under minimal assumption of exchangeability. Recently, Hoff (2023) showed that full conformal…

Statistics Theory · Mathematics 2025-11-24 Pankaj Bhagwat , Linglong Kong , Bei Jiang

Network meta-analysis (NMA) is a statistical technique for the comparison of treatment options. The nodes of the network are the competing treatments and edges represent comparisons of treatments in trials. Outcomes of Bayesian NMA include…

Methodology · Statistics 2024-01-04 Annabel L Davies , Tobias Galla

Motivated by the analysis of nonnegative data objects, a novel Nested Nonnegative Cone Analysis (NNCA) approach is proposed to overcome some drawbacks of existing methods. The application of traditional PCA/SVD method to nonnegative data…

Methodology · Statistics 2013-09-09 Lingsong Zhang , J. S. Marron , Shu Lu

Nonnegative matrix factorization (NMF) is a widely used linear dimensionality reduction technique for nonnegative data. NMF requires that each data point is approximated by a convex combination of basis elements. Archetypal analysis (AA),…

Signal Processing · Electrical Eng. & Systems 2020-03-31 Pierre De Handschutter , Nicolas Gillis , Arnaud Vandaele , Xavier Siebert

A novel method for estimating Bayesian network (BN) parameters from data is presented which provides improved performance on test data. Previous research has shown the value of representing conditional probability distributions (CPDs) via…

Machine Learning · Computer Science 2013-01-14 Geoff A. Jarrad

A fully Bayesian approach is proposed for ultrahigh-dimensional nonparametric additive models in which the number of additive components may be larger than the sample size, though ideally the true model is believed to include only a small…

Methodology · Statistics 2013-09-24 Zuofeng Shang , Ping Li

Explicit modelling of between-study heterogeneity is essential in network meta-analysis (NMA) to ensure valid inference and avoid overstating precision. While the additive random-effects (RE) model is the conventional approach, the…

Methodology · Statistics 2026-01-21 Xinlei Xu , Caitlin H Daly , Audrey Béliveau

This article studies Bayesian model averaging (BMA) in the context of competing expensive computer models in a typical nuclear physics setup. While it is well known that BMA accounts for the additional uncertainty of the model itself, we…

Methodology · Statistics 2019-08-26 Vojtech Kejzlar , Léo Neufcourt , Taps Maiti , Frederi Viens

Understanding and interpreting how machine learning (ML) models make decisions have been a big challenge. While recent research has proposed various technical approaches to provide some clues as to how an ML model makes individual…

Machine Learning · Computer Science 2018-11-09 Wenbo Guo , Sui Huang , Yunzhe Tao , Xinyu Xing , Lin Lin

Applying a machine learning model for decision-making in the real world requires to distinguish what the model knows from what it does not. A critical factor in assessing the knowledge of a model is to quantify its predictive uncertainty.…

Machine Learning · Computer Science 2023-11-15 Kajetan Schweighofer , Lukas Aichberger , Mykyta Ielanskyi , Sepp Hochreiter
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