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Many calls for explainable AI (XAI) systems in medicine are tied to a desire for AI accountability--accounting for, mitigating, and ultimately preventing harms from AI systems. Because XAI systems provide human-understandable explanations…

Human-Computer Interaction · Computer Science 2025-07-23 Gennie Mansi , Mark Riedl

The adoption of intelligent systems creates opportunities as well as challenges for medical work. On the positive side, intelligent systems have the potential to compute complex data from patients and generate automated diagnosis…

Human-Computer Interaction · Computer Science 2019-02-19 Yao Xie , Ge Gao , Xiang 'Anthony' Chen

Explainable AI (XAI) holds the promise of advancing the implementation and adoption of AI-based tools in practice, especially in high-stakes environments like healthcare. However, most of the current research lacks input from end users, and…

Machine Learning · Computer Science 2025-08-06 T. E. Röber , R. Goedhart , S. İ. Birbil

Decision-making algorithms are being used in important decisions, such as who should be enrolled in health care programs and be hired. Even though these systems are currently deployed in high-stakes scenarios, many of them cannot explain…

Computers and Society · Computer Science 2022-05-12 Gabriel Lima , Nina Grgić-Hlača , Jin Keun Jeong , Meeyoung Cha

Explanations for artificial intelligence (AI) systems are intended to support the people who are impacted by AI systems in high-stakes decision-making environments, such as doctors, patients, teachers, students, housing applicants, and many…

Human-Computer Interaction · Computer Science 2025-04-16 Gennie Mansi , Naveena Karusala , Mark Riedl

We are witnessing the emergence of an AI economy and society where AI technologies are increasingly impacting health care, business, transportation and many aspects of everyday life. Many successes have been reported where AI systems even…

Machine Learning · Computer Science 2022-12-27 D. Petkovic

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

The increasing burden of responding to large volumes of patient messages has become a key factor contributing to physician burnout. Generative AI (GenAI) shows great promise to alleviate this burden by automatically drafting patient message…

Computers and Society · Computer Science 2025-08-20 Di Hu , Yawen Guo , Ha Na Cho , Emilie Chow , Dana B. Mukamel , Dara Sorkin , Andrew Reikes , Danielle Perret , Deepti Pandita , Kai Zheng

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

Intentional and accidental harms arising from the use of AI have impacted the health, safety and rights of individuals. While regulatory frameworks are being developed, there remains a lack of consensus on methods necessary to deliver safe…

Computers and Society · Computer Science 2023-06-16 Labhaoise NiFhaolain , Andrew Hines , Vivek Nallur

In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…

Human-Computer Interaction · Computer Science 2026-05-06 Julia Wagner , Tim Schlippe

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

XAI refers to the techniques and methods for building AI applications which assist end users to interpret output and predictions of AI models. Black box AI applications in high-stakes decision-making situations, such as medical domain have…

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Artificial intelligence (AI) methods have been proposed for the prediction of social behaviors which could be reasonably understood from patient-reported information. This raises novel ethical concerns about respect, privacy, and control…

With the increasing availability of structured and unstructured data and the swift progress of analytical techniques, Artificial Intelligence (AI) is bringing a revolution to the healthcare industry. With the increasingly indispensable role…

Machine Learning · Computer Science 2020-11-09 Devam Dave , Het Naik , Smiti Singhal , Pankesh Patel

Explainable AI (XAI) techniques are necessary to help clinicians make sense of AI predictions and integrate predictions into their decision-making workflow. In this work, we conduct a survey study to understand clinician preference among…

Computation and Language · Computer Science 2025-08-28 Jun Hou , Lucy Lu Wang

With advanced AI/ML, there has been growing research on explainable AI (XAI) and studies on how humans interact with AI and XAI for effective human-AI collaborative decision-making. However, we still have a lack of understanding of how AI…

Human-Computer Interaction · Computer Science 2024-05-28 Min Hun Lee , Silvana Xin Yi Choo , Shamala D/O Thilarajah

A pervasive design issue of AI systems is their explainability--how to provide appropriate information to help users understand the AI. The technical field of explainable AI (XAI) has produced a rich toolbox of techniques. Designers are now…

Human-Computer Interaction · Computer Science 2021-09-07 Q. Vera Liao , Milena Pribić , Jaesik Han , Sarah Miller , Daby Sow

AI is becoming increasingly common across different domains. However, as sophisticated AI-based systems are often black-boxed, rendering the decision-making logic opaque, users find it challenging to comply with their recommendations.…

Artificial Intelligence · Computer Science 2024-06-19 Niklas Kühl , Christian Meske , Maximilian Nitsche , Jodie Lobana
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